KEGG   Streptococcus pyogenes Alab49 (serotype M53): SPYALAB49_001155
Entry
SPYALAB49_001155  CDS       T02019                                 
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
  KO
K01929  UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:6.3.2.10]
Organism
stz  Streptococcus pyogenes Alab49 (serotype M53)
Pathway
stz00550  Peptidoglycan biosynthesis
stz01100  Metabolic pathways
stz01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:stz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    SPYALAB49_001155 (murF)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    SPYALAB49_001155 (murF)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    SPYALAB49_001155 (murF)
Enzymes [BR:stz01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.10  UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
     SPYALAB49_001155 (murF)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C Mur_ligase
Other DBs
NCBI-ProteinID: AEQ24752
Position
complement(1120695..1122062)
AA seq 455 aa
MKLTLHEVAKIVDAQNNVSDLDDVPLHHIEFDSRKITKGDLFLPLKGQRDGHEFIDLAFQ
NGAVATFSEKELPGKPHLLVEDCLKAFQKLAHYYIDKMRVDVIAVTGSNGKTSTKDMIGA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHMGDIRLLSEIARPRIAV
LTLVGEAHLEYFGSRDKIAQGKMQIVDGMNSDGILIAPGDPIIDPYLPENQMVIRFGDHQ
ELNVTDIREEKDSLTFTTNVLATPVSLPLPGKYNATNAMVAAYVGKLLAVADEDIIEALE
SVQLTANRTEWKKAANGADILSDVYNANPTAMRLILETFANIAKNPGGKKIAVLADMKEL
GSDSVALHSQLIKQLSPDRIDQLVFYGDDIQELAQLAHEFYPEGHVQFFQKNQQEDQFED
MVRQVQQLLAPSDQILLKGSNSMGLAKLVNHLVEN
NT seq 1368 nt   +upstreamnt  +downstreamnt
atgaaattaaccttacacgaagtggctaaaatagttgacgcccaaaataatgtgtctgac
ttagacgacgttcctctgcatcacattgaatttgatagccgaaagattacaaaaggagac
ctctttttacccttaaaaggtcaaagggatggtcatgagtttattgatttagcctttcaa
aatggagctgtcgctactttttcagaaaaagaattgccggggaaacctcaccttcttgtt
gaagactgcctaaaagcttttcaaaagctagcccattattatattgataagatgcgcgtg
gatgttattgctgtgacaggctcaaatggtaaaacttccaccaaagatatgataggagct
gtcctatcaaccacttacaaaacttacaaaacgcaaggaaattacaataatgagattggt
ttgccttacaccgttctccacatgcctgacgatacggaaaaaattgttcttgaaatggga
caagatcacatgggagatattcgtctcctctctgaaattgcaagaccccgtattgcagtt
ttaaccttagtcggcgaagctcatttagaatattttggaagccgagacaaaatagcccaa
ggcaaaatgcagattgttgacggcatgaattcagatgggattttaattgctccgggagat
ccgattattgacccatatcttccagaaaatcagatggtcattcgatttggcgaccaccaa
gaattgaatgttactgatattcgagaagaaaaagatagcttaacgtttacaacaaatgtg
ttagcaacacctgtgtccctacctctaccaggaaaatacaacgcgaccaatgctatggta
gcagcctatgttggcaaattgttggcagtagcagatgaggatattatcgaggcgttagag
tctgttcaactcactgctaatcgtacagaatggaaaaaagctgctaatggtgctgacatc
ttatcagatgtttacaatgccaatccgacagccatgcgcctgattttagaaacctttgct
aacatagcaaagaaccccggtggaaaaaagattgcagtgctagctgacatgaaagaatta
ggatcagattctgttgccctacattcgcagttaatcaaacaattgtcacctgatcgcatt
gaccaacttgttttttatggtgatgatattcaagagttagcccaattagcacatgagttt
tatcctgaaggacatgttcagttcttccaaaaaaatcagcaagaagatcagtttgaagac
atggtaagacaggtgcaacaattacttgctccctctgaccaaattcttttaaaagggagt
aactcaatggggctggctaaattggtcaatcatttagttgaaaattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (23)   

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