KEGG   Staphylococcus aureus subsp. aureus TCH60: HMPREF0772_10137
Entry
HMPREF0772_10137  CDS       T01889                                 
Name
(GenBank) bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
suq  Staphylococcus aureus subsp. aureus TCH60
Pathway
suq00270  Cysteine and methionine metabolism
suq00450  Selenocompound metabolism
suq00670  One carbon pool by folate
suq01100  Metabolic pathways
suq01110  Biosynthesis of secondary metabolites
suq01120  Microbial metabolism in diverse environments
suq01230  Biosynthesis of amino acids
Module
suq_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:suq00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    HMPREF0772_10137
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    HMPREF0772_10137
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HMPREF0772_10137
Enzymes [BR:suq01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     HMPREF0772_10137
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     HMPREF0772_10137
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: ADQ75599
Position
145395..147236
AA seq 613 aa
MRQFLTHLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAYLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLEKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
NT seq 1842 nt   +upstreamnt  +downstreamnt
atgaggcaattcctcacacacttgaaagataatgttttagtagctgatggcgctattgga
actattttatactctgaaggtttagacacctgcccagaagcatataaccttagccatcca
gataaagttgaacgtatccatcgttcatatattgaagccggtgctgatgtcattcaaacc
aatacttatggtgcaaattttgaaaagttaaaacgattcggtcttgaagataaagttaag
gctatacatcaagcagccgttcgcatcgcaaaaaaagcagcaaataaagatacgtatata
ttaggcacagttggtgggtttagaggtatcaaacaagaggatatcagcttacaaactatt
ctttatcatactgaaattcaaatagacaccttgattgaagaaggtgttgacgcgctactt
ttcgaaacgtattacgacctagaagagctaacaaatgtcatttcacgaacgagaaagaaa
tacgacattccaatcattgctcaattaaccgcttcaaacacaaattacttagttaatggt
caggcaatcaatgaaggattaaaacaactcgttcaatgtggtgcaaacatcgtgggactc
aattgtcatcatggcccacaccatatgcaagagtctttcacacatattgaattaccagag
cacgcatacttatcttgttatccaaatgccagcttattagatattgaaaatagtgaattt
aagtatagtgacaatgcacaatatttcggtcaagttgctcaaaatctaattcgcgaaggt
gttcgtttaattggtggttgctgtggtacaacgcctgagcacatcaaatttattaaagaa
tctattcagacacttaaacctgttaatgacaaaaaagtgattccgataccaacgaaagca
cttttcaatccatctcaaaataaagttagacaatcattaacatctaaggttcaagaacgt
ccaaccgttattatcgaattggatacaccgaaacatttagacacggatagattttttgaa
aatatcgctaaacttgaaaaagctaatgtagatgcggtaacactcgcagataattcattg
gcaactgtcagaattagcaacattgctgctgcaagcttaattaaacaatattacaatatt
gaaccactcgtacatattacatgtcgagaccgaaacttaatcggcttgcagtctcattta
cttggattatcactcattggcgttaacgaaatattagccataactggtgatccttcaaaa
gttggtcacctacctggtgcaaccaatgtctatgatgttaattctaaaggattaactgaa
ctcgctctaagatttaatcaaggtattaacactgacggtgatgcgctgaagaaacgtaca
cacttcaacatcgctggcgcctttaaccctaatgttcgtaaattagatggtgccgtaaaa
cgactagagaaaaagatagaaagcggaatgtcttattttataacacaacccgtgtacagc
aaagagaaaatcattgaaatttaccatgccactaagcacttgaacaaaccatttttcata
ggcattatgcctatcgcaagttacaaaaacgcactctttttgcataatgaagtgccagga
atcaagatgtcagatgaaattttacaacaatttgaagcagttaaagatgataaagccaaa
actcgtgaactaagccttaagctttcaaaggatttaatcgatactgttcatgaatatttt
aatggtttatacattatcacaccgtttcaaaatgtcgaagattcattagaacttgcagca
tactcaaaatctattactgctcacaaggaggcaatattatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (34)   

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