KEGG   Staphylococcus aureus subsp. aureus T0131 (MRSA): SAT0131_00364
Entry
SAT0131_00364     CDS       T01888                                 
Name
(GenBank) Methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
sut  Staphylococcus aureus subsp. aureus T0131 (MRSA)
Pathway
sut00270  Cysteine and methionine metabolism
sut00450  Selenocompound metabolism
sut00670  One carbon pool by folate
sut01100  Metabolic pathways
sut01110  Biosynthesis of secondary metabolites
sut01120  Microbial metabolism in diverse environments
sut01230  Biosynthesis of amino acids
Module
sut_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:sut00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    SAT0131_00364
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    SAT0131_00364
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SAT0131_00364
Enzymes [BR:sut01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     SAT0131_00364
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     SAT0131_00364
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: AEB87463
Position
complement(376592..378433)
AA seq 613 aa
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPTKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLYGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
NT seq 1842 nt   +upstreamnt  +downstreamnt
atgagtcaattcctcacacaattgaaagataatgttttagtagctgatggcgctatagga
accattttatactctgaaggattagacacctgtccagaagcatataatcttagccatcca
gataaagttgaacgcatccatcgttcatatattgaagccggtgctgatgtcattcaaacc
aatacttatggtgcaaattttgaaaagttaaaacgattcggtcttgaagataaagttaaa
gcaatacatcaagccgccgttcgcatcgcaaaaaaagcagcaaataaagatacgtatata
ttaggcacagttggtgggtttagaggtatcaaacaagaggatatcagcttacaaactatt
ctttatcatactgaaattcaaatagacaccttaattgaagaaggcgttgacgcgctactt
ttcgaaacgtattacgacctagaagagttaacaaatgtcatttcacgaacgagaaagaaa
tacgacattccaatcattgctcaattaaccgcttcaaacacaaattacttagttaatggt
caggcaatcaatgaaggattaaaacaactcgttcaatgtggtgcaaacatcgtgggactc
aattgtcatcatggcccgcaccatatgcaagagtctttcacacatattgaattaccagag
cacgcattcttatcttgttatccaaatgccagcttattagatattgaaaatagtgaattt
aagtatagtgacaatgcacaatatttcggtcaagttgctcaaaatctaattcgcgaaggt
gttcgtttaattggtggttgctgtggtacaacgccagagcacatcaaatttattaaagaa
tctattcagacacttaaacctgttaatgacaaaaaagtgattccgataccaacgaaagca
cttttcaatccatctcaaaataaagttagacaatcattaacatctaaggttcaagaacgt
ccaaccgttattatcgaattggatacaccgaaacatttagacacggatagattttttgaa
aatatcgctaaacttgataaagctaatgtagatgcggtaacactcgcagataattcattg
gcaactgtcagaattagcaatattgctgctgctagcttaattaagcaatattacaatatt
gaaccactcgtacatattacatgtcgagaccgaaacttaatcggcttgcagtcccattta
cttggattatcgctcattggcgttaacgaaatattagccataactggtgatccttcaaaa
gttggtcacttaccaggtgcaaccaatgtctatgatgttaattctaaaggattaactgaa
ctcgctctaagatttaatcaaggtattaacactgacggtgatgcgctgaagaaacgtaca
cacttcaacatcgctggcgcctttaaccctaatgttcgtaaattatatggtgccgtcaaa
agattagagaaaaagatagaaagcggaatgtcttattttataacacaacccgtgtacagc
aaagagaaaatcattgaaatttaccatgccactaagcacttgaacaaaccatttttcata
ggcattatgcctatcgcaagttacaaaaacgcactctttttgcataatgaagtgccagga
atcaagatgtcagatgaaattttacaacaatttgaagcagttaaagatgataaagccaaa
acacgagaactaagtcttaagctttcaaaggatttaatcgatactgttcatgaatatttt
aatggtttatacattatcacaccgtttcaaaatgtcgaagattcattagaacttgcagca
tactcaaaatctattactgctcacaaggaggcaatattatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (34)   

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