KEGG   Staphylococcus aureus subsp. aureus M013 (CA-MRSA): M013TW_1941
Entry
M013TW_1941       CDS       T01744                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
suu  Staphylococcus aureus subsp. aureus M013 (CA-MRSA)
Pathway
suu03030  DNA replication
suu03410  Base excision repair
suu03420  Nucleotide excision repair
suu03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:suu00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    M013TW_1941 (ligA)
   03410 Base excision repair
    M013TW_1941 (ligA)
   03420 Nucleotide excision repair
    M013TW_1941 (ligA)
   03430 Mismatch repair
    M013TW_1941 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:suu03032]
    M013TW_1941 (ligA)
   03400 DNA repair and recombination proteins [BR:suu03400]
    M013TW_1941 (ligA)
Enzymes [BR:suu01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     M013TW_1941 (ligA)
DNA replication proteins [BR:suu03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     M013TW_1941 (ligA)
DNA repair and recombination proteins [BR:suu03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     M013TW_1941 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     M013TW_1941 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     M013TW_1941 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      M013TW_1941 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT DNA_ligase_ZBD HHH_5 RNA_pol_A_CTD zf-NADH-PPase PTCB-BRCT HHH zf-IS66
Other DBs
NCBI-ProteinID: AEV78952
Position
complement(2002918..2004921)
AA seq 667 aa
MADLSSRVNELHDLLNQYSYEYYVEDNPSVPDSEYDKLLHELIKIEEEHPEYKTVDSPTV
RVGGEAQASFNKVNHDTPMLSLGNAFNEDDLRKFDQRIREQIGNVEYMCELKIDGLAVSL
KYVDGYFVQGLTRGDGTTGEDITENLKTIHAIPLKMKEPLNVEVRGEAYMPRRSFLRLNE
EKEKNDEQLFANPRNAAAGSLRQLDSKLTAKRKLSVFIYSVNDFTDFNACSQSEALDELD
KLGFTTNKNRARVNNIDGVLEYIEKWTSQRESLPYDIDGIVIKVNDLDQQDEMGFTQKSP
RWAIAYKFPAEEVVTKLLDIELSIGRTGVVTPTAILEPVKVAGTTVSRASLHNEDLIHDR
DIRIGDSVVVKKAGDIIPEVVRSIPERRPEGAVTYHMPTHCPSCGHELVRIEGEVALRCI
NPKCQAQLVEGLIHFVSRQAMNIDGLGTKIIQQLYQSELIKDVADIFYLTEEDLLPLDRM
GQKKVDNLLAAIQQAKDNSLENLLFGLGIRHLGVKASQVLAEKYETIDRLLTVTEAELVE
IHDIGDKVAQSVVTYLENEDIRALIQKLKDKHVNMIYKGIKTSDIEGHPEFSGKTIVLTG
KLHQMTRNEASKWLASQGAKVTSSVTKNTDVVIAGEDAGSKLTKAQSLGIEIWTEQQFVD
KQNELNS
NT seq 2004 nt   +upstreamnt  +downstreamnt
atggctgatttatcgtctcgtgtgaacgagttacatgatttactaaatcaatacagttat
gaatactatgtagaggataatccatctgtaccagatagtgaatatgacaaattacttcat
gaactgattaaaatagaagaggagcatcctgagtataagactgtagattctccaacagtt
agagttggcggtgaagcccaagcctctttcaataaagtcaaccatgacacgccaatgtta
agtttagggaatgcatttaatgaggatgatttgagaaaattcgaccaacgcatacgtgaa
caaattggcaacgttgaatatatgtgcgaattaaaaattgatggcttagcagtatcattg
aaatatgttgatggatacttcgttcaaggtttaacacgtggtgatggaacaacaggtgaa
gatattaccgaaaatttaaaaacaattcatgcgatacctttgaaaatgaaagaaccatta
aatgtagaagttcgtggtgaagcatatatgccgagacgttcttttttacgattaaatgaa
gaaaaagaaaaaaatgatgagcagttatttgcaaatccaagaaacgctgctgcgggatca
ttaagacagttagattctaaattaacggcaaaacgaaagctaagcgtatttatatatagt
gtcaatgatttcactgatttcaatgcgtgttcgcaaagtgaagcattagatgagttagat
aaattaggttttacaacgaataaaaatagagcgcgtgtaaataatatcgatggtgtttta
gagtatattgaaaaatggacaagccaaagagagtcattaccttatgatattgatgggatt
gttattaaggttaatgatttagatcaacaggatgagatgggattcacacaaaaatctcct
agatgggccattgcttataaatttccagctgaggaagtagtaactaaattattagatatt
gaattaagtattggacgtacaggtgtagtcacacctactgctattttagaaccagtaaaa
gtagctggtacaactgtatcaagagcatctttgcacaatgaagatttaattcatgacaga
gatattcgaattggtgatagtgttgtagtgaaaaaagcaggtgacatcatacctgaagtt
gtacgtagtattccagaacgtagacctgagggtgctgtcacatatcatatgccaacccat
tgtccaagttgtggacatgaattagtacgtattgaaggcgaagtagcacttcgttgcatt
aatccaaaatgccaagcacaacttgttgaaggattgattcactttgtatcaagacaagcc
atgaatattgatggtttaggcactaaaattattcaacagctttatcaaagcgaattaatt
aaagatgttgctgatattttctatttaacagaagaagatttattaccattggatagaatg
gggcagaaaaaagttgataatttattagctgccattcaacaagctaaggacaactcttta
gaaaatttattatttggtttaggtattaggcatttaggtgttaaagcgagccaagtgtta
gcagaaaaatatgaaacgatagatcgattactaacggtaactgaagcggaattagtagaa
attcatgatataggcgataaagtagcacaatctgtagttacttacttagaaaatgaagat
attcgtgctttaattcaaaaattaaaagataaacatgttaatatgatttataaaggtatc
aaaacatcagatattgaaggacatcctgaatttagtggtaaaacgatagtactaactggt
aagctacatcaaatgacacgcaatgaagcatctaaatggcttgcatcacaaggtgctaaa
gttacaagtagcgttactaaaaatacagatgtcgttattgctggtgaagatgcaggttca
aaattaacaaaagcacaaagtttaggtattgaaatttggacagagcaacaatttgtagat
aagcaaaatgaattaaatagttag

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (11)   
   Pfam (11)   
All databases (30)   

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