KEGG   Staphylococcus aureus subsp. aureus 11819-97 (CA-MRSA): MS7_0347
Entry
MS7_0347          CDS       T01950                                 
Name
(GenBank) methylenetetrahydrofolate reductase family protein
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
suz  Staphylococcus aureus subsp. aureus 11819-97 (CA-MRSA)
Pathway
suz00270  Cysteine and methionine metabolism
suz00450  Selenocompound metabolism
suz00670  One carbon pool by folate
suz01100  Metabolic pathways
suz01110  Biosynthesis of secondary metabolites
suz01120  Microbial metabolism in diverse environments
suz01230  Biosynthesis of amino acids
Module
suz_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:suz00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    MS7_0347
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    MS7_0347
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    MS7_0347
Enzymes [BR:suz01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     MS7_0347
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     MS7_0347
SSDB
Motif
Pfam: S-methyl_trans MTHFR DUF6506
Other DBs
NCBI-ProteinID: AEW64380
Position
complement(394687..396528)
AA seq 613 aa
MSQFLTQLKDNVLVADGAIGTILYSEGLDTCPEAYNLSHPDKVERIHRSYIEAGADVIQT
NTYGANFEKLKRFGLEDKVKAIHQAAVRIAKKAANKDTYILGTVGGFRGIKQEDISLQTI
LYHTEIQIDTLIEEGVDALLFETYYDLEELTNVISRTRKKYDIPIIAQLTASNTNYLVNG
QAINEGLKQLVQCGANIVGLNCHHGPHHMQESFTHIELPEHAFLSCYPNASLLDIENSEF
KYSDNAQYFGQVAQNLIREGVRLIGGCCGTTPEHIKFIKESIQTLKPVNDKKVIPIPKKA
LFNPSQNKVRQSLTSKVQERPTVIIELDTPKHLDTDRFFENIAKLDKANVDAVTLADNSL
ATVRISNIAAASLIKQYYNIEPLVHITCRDRNLIGLQSHLLGLSLIGVNEILAITGDPSK
VGHLPGATNVYDVNSKGLTELALRFNQGINTDGDALKKRTHFNIAGAFNPNVRKLDGAVK
RLEKKIESGMSYFITQPVYSKEKIIEIYHATKHLNKPFFIGIMPIASYKNALFLHNEVPG
IKMSDEILQQFEAVKDDKAKTRELSLKLSKDLIDTVHEYFNGLYIITPFQNVEDSLELAA
YSKSITAHKEAIL
NT seq 1842 nt   +upstreamnt  +downstreamnt
atgagtcaattcctcacacaattgaaagataatgttttagtagctgatggcgctattgga
accattttatactctgaaggattagacacctgtccagaagcatataatcttagccatcca
gataaagttgaacgtatccatcgttcatatatcgaagctggtgctgatgtcattcaaacc
aatacttatggtgcaaattttgaaaagttaaaacgattcggtcttgaagataaagttaaa
gctatacatcaagccgccgtacgcatcgcaaaaaaagcagcaaataaagatacgtatata
ttaggcacagttggtgggtttagaggtatcaaacaagaggatatcagcttacaaactatt
ctttatcatactgaaattcaaatagacaccttaattgaagaaggcgttgacgcgctactt
ttcgaaacgtattacgacctagaagagctaacaaatgtcatttcacgaacgagaaagaaa
tacgacattccaatcattgctcaattaaccgcttcaaacacaaattacttagttaatggt
caggcaatcaatgaaggattaaaacaactcgttcaatgtggtgcaaacatcgtgggactc
aattgtcatcatggcccgcaccatatgcaagagtctttcacacatattgaattaccagag
cacgcattcttatcttgttatccaaatgccagcttattagatattgaaaatagtgaattt
aagtatagtgacaatgcacaatatttcggtcaagttgctcaaaatctaattcgcgaaggt
gttcgtttaattggtggttgctgtggtacaacgccagagcacatcaaatttattaaagaa
tctattcagacacttaaacctgttaatgacaaaaaagtgattccgataccaaagaaagca
cttttcaatccatctcaaaataaagttagacaatcattaacatctaaggttcaagaacgt
ccaaccgttattatcgaattggatacaccgaaacatttagacacggatagattttttgaa
aatatcgctaaacttgacaaagctaatgtagatgcggtaacactcgcagataattcattg
gcaactgtcagaattagcaacattgctgctgcaagcttaattaaacaatattacaatatt
gaaccactcgtacatattacttgtcgagaccgaaacttaatcggcttgcagtcccattta
cttggattatcgctcattggcgttaacgaaatattagccataactggtgatccttcaaaa
gttggtcacttaccaggtgcaaccaatgtctatgatgttaattctaaaggattaactgaa
ctcgctctaagatttaatcaaggtattaacactgacggtgatgcgctgaagaaacgtaca
cacttcaacatcgctggcgcctttaatcctaatgttcgaaaattagatggtgccgtcaaa
agattagagaaaaagatagaaagcggaatgtcttattttataacacaacccgtgtacagc
aaagagaaaatcattgaaatttaccatgccactaagcacttgaacaaaccatttttcata
ggcattatgcctatcgcaagttacaaaaacgcactctttttgcataatgaagtgccagga
atcaagatgtcagatgaaattttacaacaatttgaagcagttaaagatgataaagccaaa
acacgagaactaagtcttaagctttcaaaggatttaatcgatactgttcatgaatatttt
aatggtttatacattatcacaccgtttcaaaatgtcgaagattcattagaacttgcagca
tactcaaaatctattactgctcacaaggaggcaatattatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (5)   
   KEGG ENZYME (2)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (34)   

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