KEGG   Thermus aquaticus: TO73_1340
Entry
TO73_1340         CDS       T04117                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
taq  Thermus aquaticus
Pathway
taq00290  Valine, leucine and isoleucine biosynthesis
taq00620  Pyruvate metabolism
taq01100  Metabolic pathways
taq01110  Biosynthesis of secondary metabolites
taq01210  2-Oxocarboxylic acid metabolism
taq01230  Biosynthesis of amino acids
Module
taq_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:taq00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    TO73_1340
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    TO73_1340
Enzymes [BR:taq01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     TO73_1340
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Guanylate_kin
Other DBs
NCBI-ProteinID: ALJ91183
Position
complement(1195953..1197515)
AA seq 520 aa
MEKERHIRIFDTTLRDGEQSPGVALSLDQKLEIAHALARLNVDIIEAGFPVSGPLEFEAV
RRIAAEVKGPVIAALARTHTLDIDQAARALEKAEKPRIHVFTSASKIHLQYMLKKTEEEV
LEMADEMVRYARKYVDDVEFSAQDVMRAEWDFVKRLYEVAIEAGATTINIPDTTGYGTPE
EYGALIRRIRDEVVRGRDVVISTHTHDDLGLATANALAGILNGAGQVECTVNGIGERAGN
TAMEEVVMALYVRRDFYKAYTQVNTREIYRVSRLVERYTGMPVPPNKAIVGDNAFAHESG
IHQDGVLKHRGTYEIMDAELIGRRPAVLVLGKHSGRAAFKKALEDLGYKDLTEEQLKVLF
SRFKEIAEKKGPLSAEELQALVETGLEPASRFFELKHVQFFSGSGLLPTATVRVMTPDGE
KVATHTGDGPVDAVYKAIEEAIGLKPELELYRVEAITGSTEALGQVTVRLRLGELQAVGV
GVSPDIIEASALAFLDAAGKLASGRATRHPPSIEEVHRGV
NT seq 1563 nt   +upstreamnt  +downstreamnt
atggagaaggaaaggcacatccgcatctttgacaccacgctccgcgacggcgagcagagc
cctggcgtggcgctctccctggaccagaagctggagatcgcccacgccctggcccggctc
aacgtggacatcattgaggcgggcttccccgtatcggggcctttggagtttgaggcggtg
aggcgcatcgccgccgaggtcaaggggcccgtcatcgccgctttggcccggactcacacc
ctggacattgaccaggcggccagggccctggagaaggcggaaaagcccaggatccacgtc
ttcacttccgcctccaagatccacctccagtacatgctgaagaagacggaggaggaggtc
ctggagatggcggacgagatggtccgctacgccaggaagtacgtggacgacgtggagttt
tccgcccaggacgtgatgcgggcggagtgggacttcgtcaagaggctttacgaggtggcc
attgaggcgggggccaccaccatcaacatccccgacaccacgggctacggcacccccgag
gagtacggggccctgatccgcaggatccgggatgaggtggttcggggccgggacgtggtc
atctccacccacacccacgacgacctgggcctggccacggccaacgccctggcgggaatc
ttgaacggggccgggcaggtggagtgtaccgtaaacggcatcggcgagcgggcggggaac
accgccatggaggaggtggtcatggccctctacgtgcgccgggacttttacaaggcctac
acccaggtgaacacccgggagatctaccgggtgtcccggctggtggagcgctacaccggc
atgcccgtcccccccaacaaggccatcgtgggggacaacgccttcgcccacgagtcgggc
atccaccaggacggggtcctgaagcaccggggcacctacgagatcatggacgcggagctc
atcggcaggaggcccgccgtcctcgtcctcggcaagcactcgggccgggcggccttcaag
aaggccctcgaggacctgggctacaaggacctcaccgaggagcagctgaaggtcctcttc
agccgcttcaaggagatcgccgagaagaaggggcctctctcggccgaggagctccaggcc
ctggtggagaccgggctggagcccgcctcccgcttctttgagctcaagcacgtccagttc
ttctctggctccggcctcctgcccacggccacggtgcgggtgatgaccccggacggggaa
aaggtggccacccacaccggggacgggcctgtggacgccgtttacaaggccattgaggag
gccatcggcctcaagcccgagctggagctttaccgggtggaggccatcaccgggagcacc
gaggccctgggccaggtgaccgtgcgccttcgccttggcgagctccaggcggtgggggtg
ggggtttccccggacatcattgaggccagcgccctggccttcctggacgccgccggcaag
ctggcctcgggccgggccacccggcacccgccctccattgaggaggtccaccgcggggtc
tag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (23)   

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