KEGG   Trypanosoma brucei brucei: Tb09.211.1820
Entry
Tb09.211.1820     CDS       T01013                                 
Name
(RefSeq) DNA polymerase epsilon catalytic subunit, putative
  KO
K02324  DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
Organism
tbr  Trypanosoma brucei brucei
Pathway
tbr03030  DNA replication
tbr03410  Base excision repair
tbr03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:tbr00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Tb09.211.1820
   03410 Base excision repair
    Tb09.211.1820
   03420 Nucleotide excision repair
    Tb09.211.1820
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:tbr03032]
    Tb09.211.1820
   03400 DNA repair and recombination proteins [BR:tbr03400]
    Tb09.211.1820
Enzymes [BR:tbr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     Tb09.211.1820
DNA replication proteins [BR:tbr03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    Tb09.211.1820
DNA repair and recombination proteins [BR:tbr03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      Tb09.211.1820
SSDB
Motif
Pfam: DNA_pol_B_exo1 DUF1744 DNA_pol_B DNA_pol_B_exo2 RNase_H_2 Cytochrome_C7
Other DBs
NCBI-GeneID: 3660717
NCBI-ProteinID: XP_827328
UniProt: Q38DX2
Position
9:complement(1580562..1587302)
AA seq 2246 aa
MNCSVQMPPPQDEWPIMESGTRTGWLFNYHPTSVAAPESAFDRHGGSGVRAALVLLFTDH
EREVFQVNLFYNPYIFVSAVEGHEHEVELGMMSLFGPQLICHIEIVEKEDLDLINHLSGR
KRLYLKVSFSNVQDLTTVRGRLEKIVKRNASMGASNTLLNPLDRSIGDVMAKTFEDDPVN
STTASERWFDWVHEIREYDVKYSMRVGIDLGVFVGLWYDVKVHEGETQLIRCDLNAYAPA
MPRVCAFDIETTKAPLKFPQPEVDQIYMISYVLDGRGYLIVNREIVATDIHQFEYTPKPE
YEGIFDTFNEPDEKALLQRFYSEMRLYQPTVYVTYNGDYFDFPFIHARSLFHHLSMREEL
GFSQNSEGAFVANKLVHLDCFYWVKRDSYLPQGSQGLKAVTKYKLGYEPIEVDPEDMLPL
AQSNPQQMASYSVSDALSTWFLYQKYVHPFIYSLSTIIPMAPDDVLRKGSGGLCESLLMV
QAYANNVIFPNKKEIKLERFFNGHLIDSETYIGGRVEALRSGVYRSDIPIHFQMSADMYQ
KLIDDLDDALRFSLEVENSVKMNEVTNYEEIRDSIKARLEVLRDRPSQYATPIIYHLDVG
AMYPNIILTNRLQPYAIPKAEVCAGCCFNSPTNEHFCKRTMAWKWKGEFLTAGRHEYQRV
KAQLENESFAESVIQQANLSAVQKKTYGNRKDNVLEGTAYEKKRRPFAKRQNDVKSDYRH
ENNFQRQEARNALLHKEFQKDQDGSGSDEDEDAGGPKAYYKLQESTKFNMLKKRLAEYSR
KAYGKIHESREIMRSDVVCQRENSFYVDTVRLFRDRRYEYKAALKTWKKRLDNAKDTEEI
KLCKSRCVQMESLQLAHKCILNSFYGYVMRKGSRWYSMEMAGIVTYLGATLIQMARALVQ
QIGVTLELDTDGIWCCLPNTFPENFTFTTTNPSTPKVTISYPCIVLNKMVHDGYTNHQYQ
TCVGPGLYERRSECSIYFEVDGPYLAMMLPASREEGKGIKKRYAVFDPDGRLADLKGFEL
KRRGELMLIKDFQSQVFRRFLDGTTLVESYASAAVAANVALDMLYSKGEGYDPEEILEKL
SESSNMTRRLSEYPDSQKSLALTTARRIGDFLGPQMVKDKGLACQFVISRLPSGRPVTER
AIPLTIFRADPAIRTHFLRKWTGDNSISANVDLQHLLDWDYYIARYNACVQKIITIPAAL
QQVPNPVPRVPYPDWLQKRVQQLNSRFKQTTLTNMFVKAKPGDGGVPDVEDLVTGDGVAP
SSGGEKDVRRKKNGSAGVVNGDVYYLQESEGTDSDVASIVNVSDDEGYRLVREAELHEIE
DVEMLKSKYFAPNSNHPMDAAFFADARVGAWLKLQKQAWTRRATLRRQMMKESELLTADG
QPTSSHFIDVKTKALSTTWHIMEIRTDKADDGTVAVIAALDKTLYTFRCIVPRRIVVDAD
HNAFLPSAKPVTNALVLPRSRSSTNLLHVDLPPGREGERMLNGLLTGREDVHMVYEDHIT
RAEVMIEKIGCCANVLVDDYLRNARQRPYARGTFSVDELTSVPTGNYLQNSSNRFVFLFH
VASDTRGIIGLVNHFDHTAFVAIIQPASAPAPTINWRTLFFEAAQSLNSTEVPLDVTWEV
VADTENAWRLVYRSLNGVMEGGGSPLFAVLESSITTTQLIEQRCLPSSLPYLRILGAAED
ERLLSDPFRWTRLLARRLLQRYCASLLWVEERISFSRLSRIPLCNLMQDTSVHAWDVLFT
RALHARAHVLWNSRDVSIAFDSIEERPRQVVMPGGYLSWGVEFSLARLDVVAVLFSQLIQ
EGDDPNAHALCNQGVTTHFNILRDLVSDLLGQVRTNAVADVLLASFSRWIRDPVSSCYEP
RLLELVSTLAHRALTTVLFSLAKLGGRTVKVDGDSIVVLTPKHTIQDTVSFARFMVDSLK
DQPMLLLLSLKPIRYWCPFVILDKRDYVFLYVTSEGCKSLKEKDQVVLDEMLVEYSFTIW
SKLPKKVRDILLVRIEGTLRAIALARESVLVEVQEDPTVVLATKNEQILTRIVGVYKKLV
EGKLHTELIEEVHDLTERKDLHEKGFPAGETTLTGAAVALEYTKVVCRLLELFPNDGVLG
KVRNNCLRLCGVSPFSPLAQITADADTDCHQLMFQCSFCNADVLLDLSIREKRMRCNGCS
APIFASAVESYLVRKVNTLVMSYTKQDFVCGKCHEVTANSINQTCCGPLVGKAKPIHTQL
QALKKVAVIQGFAWLEECVETALQFS
NT seq 6741 nt   +upstreamnt  +downstreamnt
atgaattgtagcgtacaaatgccacccccacaagatgagtggccgattatggagagtggc
acccggaccggttggctgtttaattatcacccaacaagtgttgcagcaccggagtccgct
tttgatcggcatggtggctcaggcgtacgcgctgcgctggttcttctattcacagatcac
gagcgtgaagtatttcaggtaaatttgttttacaatccctacatatttgtctccgcagtt
gagggtcacgagcatgaggtagagctcggcatgatgtcgctgtttggaccgcaattgatc
tgtcatatcgaaattgtggagaaagaagaccttgacctcattaaccatttgagcggccgc
aagcgcctgtacctaaaggtttccttctctaatgtgcaggaccttactaccgttcgtggt
cgtttagagaagatagtgaaacgaaacgcatcgatgggcgcaagcaatacgctgctcaac
ccacttgacaggtcgatcggggacgtgatggccaaaacatttgaggatgaccctgttaat
agtaccaccgcatcagaaaggtggtttgactgggttcacgaaatacgggaatatgacgtg
aagtacagcatgcgtgtggggattgaccttggtgtttttgtgggattatggtatgacgtc
aaagttcacgaaggggaaacgcagctgatccgctgtgatcttaatgcatacgcaccggct
atgccacgcgtgtgtgcgtttgatatcgaaacgacaaaagcaccactaaagttcccacaa
cctgaggtggatcaaatttacatgatttcgtatgtgcttgacgggcgtgggtatctgatc
gtcaaccgcgaaattgtggccacagatattcatcagttcgaatacacgcccaagcccgag
tatgaagggatatttgatacctttaatgaaccagatgaaaaggcattgctgcaacgtttc
tacagtgagatgcgtctataccagccaactgtgtatgttacgtataacggagactatttc
gactttcctttcatccacgcacgctcattattccaccatctaagcatgcgagaagaactg
ggcttttcgcagaactctgagggggcgtttgtagctaacaaattagtgcatttggattgc
ttttactgggtgaagcgggacagctacctcccgcaaggtagtcaaggtctgaaggcggta
acgaagtacaaactgggatatgagccaatagaagtcgatccggaggatatgttgccactt
gcacaaagcaacccacaacagatggcgtcgtactctgtctccgacgccttgtcaacatgg
tttctttaccaaaagtacgttcatccttttatttactcactatccacgataattcccatg
gccccggatgacgtgcttcggaagggctctggtggtctttgcgagtcgttgctcatggtg
caagcgtatgcaaataacgttatttttcccaacaagaaggagattaaattggaaagattt
ttcaacggtcacctgattgatagtgaaacatacatcggtggccgggttgaggctcttcgc
agtggtgtttaccgcagtgatattcccatacattttcaaatgagtgctgacatgtatcaa
aagctcatcgacgatctcgacgacgcgctgcgattctcattagaagtggaaaacagtgta
aagatgaatgaagtgacaaattacgaggaaatccgtgatagcatcaaagctagacttgaa
gttctacgtgatcgaccatctcagtatgccacgcccatcatataccatctggacgtcggt
gcaatgtacccgaacattattctcacaaataggttgcaaccttacgccattccgaaggct
gaggtgtgcgcgggatgttgtttcaattctccgacgaacgaacacttctgcaaaaggact
atggcgtggaaatggaagggtgaattccttacagcgggtcgccatgagtatcaacgtgtc
aaggcgcagctggagaacgagtcttttgcggaatcggttattcagcaggccaacctatca
gctgtccaaaagaaaacgtacggcaaccgcaaagacaatgttttggagggaactgcgtac
gaaaagaagaggcgccccttcgcgaaacgacagaacgatgtcaagagcgactacaggcac
gagaacaactttcagcgccaggaggcgcggaatgcactgctgcataaggagttccaaaag
gatcaagatggctccggtagcgatgaggatgaggatgcaggtggccctaaggcgtattac
aaattacaggagtccacaaagtttaacatgctcaagaagcgccttgccgagtacagcagg
aaggcttacggcaaaatccacgaatcccgtgagatcatgcggagcgacgttgtttgtcag
cgcgaaaactccttctacgtggacacagtgcgtctgtttcgagaccgcagatacgagtac
aaagcggccctcaaaacgtggaagaagaggttggacaatgccaaagacaccgaagaaatc
aagctttgcaaaagtcgttgtgtgcaaatggagtccctccagctagctcacaagtgcatt
ctgaactcattctatggctacgtaatgcgcaaagggagccgctggtacagcatggaaatg
gctggcattgtcacatacctcggtgccacgctgattcaaatggcgcgtgcgctagtacaa
cagattggagtcacccttgaattggatacggatggcatttggtgctgccttccgaacacc
ttcccagagaactttaccttcacaacaactaacccatcgacaccaaaggtgactatttcc
tacccctgtattgtgctcaacaaaatggtgcatgacggatatacaaaccatcagtaccaa
acttgcgttggacccggtttgtacgaacgccgtagcgagtgctccatatattttgaagtt
gatgggccctatctagcaatgatgctcccagcgagtagggaggaggggaaaggtattaag
aaacgttacgccgtgtttgacccggacggccgacttgctgatttgaaggggttcgagctc
aagcgacgtggggagttgatgcttataaaggattttcaatcgcaggtgtttcgtcgcttc
ttggacggcaccaccctggttgaatcgtatgcctcagcggccgttgcagctaacgtcgca
ctcgacatgttgtactccaagggcgagggctacgacccagaggagattcttgagaagctg
tcggagagcagcaacatgactcgacgtctgtcagaatatcctgactcgcagaagtccctt
gcactgacaacagctcgacgtattggagacttccttggtccacagatggttaaagataag
ggacttgcttgccaattcgtgatctcgcgtcttcccagcggccgccctgttactgagcgg
gcgattccactcactattttccgggcagatcctgccattcgcacacacttcttacgcaaa
tggacgggtgacaactccatatccgctaatgtagaccttcaacatttgcttgactgggat
tattacattgctcgctacaacgcatgcgtgcagaaaattataacgattcctgccgcgcta
cagcaggtccccaacccagtcccacgagtgccgtacccggactggcttcagaagcgtgtt
caacaactgaactcaagattcaagcaaacgacgctgacaaatatgttcgtcaaggctaaa
ccaggtgacggtggtgtgcctgatgtggaggatcttgttacgggcgatggggtggccccc
tcatccggtggagagaaagatgtgcgtcgtaagaagaatggttctgcaggggtggttaac
ggcgatgtttactaccttcaagaaagcgaaggtactgactcggacgttgctagtatcgtt
aatgtgtctgacgatgagggataccgccttgtgcgtgaggcagagttacatgaaattgag
gatgttgaaatgctaaagtccaagtattttgcaccgaacagcaaccaccctatggatgcc
gctttcttcgcagatgcacgtgtgggggcttggttgaagctgcagaagcaagcgtggaca
cgtcgcgctacgttacgccgacaaatgatgaaagaaagtgagttactcacagcggatgga
cagccaactagcagccacttcattgatgtgaaaactaaagcactatcgacaacctggcat
atcatggaaatacgaacggacaaagctgacgacggtacggtggcggttatcgcagctctg
gataaaaccctctacaccttccggtgcattgttccacggcgcattgttgttgatgccgat
cataatgcatttttaccctccgcgaaacctgttaccaatgcgcttgttttacctcgaagt
cgaagctcgacaaacctgttgcatgttgatttacctccgggtcgagagggcgaaagaatg
ctgaatggattactcacaggacgagaggatgtccacatggtttatgaggatcacattaca
cgagctgaggtgatgattgaaaaaatcgggtgctgtgcgaacgttttagttgacgattat
ctgcgaaacgcgaggcagagaccatatgcaagagggacttttagcgtagatgaacttacg
agtgtccccaccggaaattacctccaaaattcgtctaaccgttttgtatttctttttcac
gtcgcttccgacacccgcggcataattgggcttgtgaaccacttcgatcatactgctttc
gtagctataattcaaccagcctcggcgcctgccccaacaataaattggagaacattgttc
tttgaggcagcacagtctctcaacagtactgaggttccgctggatgtgacgtgggaggtc
gtcgcagataccgaaaatgcgtggcgactcgtctatcgctcactaaatggagtgatggaa
ggagggggctcaccgttgtttgctgtccttgaaagtagtatcactacgacgcaacttatt
gaacaacgttgccttccgtcatcactcccatatctccgtatccttggtgcagcggaggat
gaacgcctgctttctgatccattccggtggacacggttactcgcacggaggctgctgcag
cgctattgtgcatctctactttgggtagaggagcgcatctcatttagtcgcctctcccgt
atccctctatgcaatctgatgcaagacacgagtgtccatgcttgggatgtgctcttcacg
agagcactgcatgctcgtgcccatgtcttatggaactcgcgtgatgtatctatcgccttc
gattccatagaggagcgaccgcggcaggttgtcatgcccggtggttacctttcgtggggc
gttgagtttagtttggcgcggctcgatgtggtcgccgtgttgttctcacagttgattcaa
gaaggcgatgaccctaatgcccatgctctgtgcaaccaaggtgtaaccacacactttaac
atactgcgagatctcgtctcggatttgttgggtcaagtgcgaaccaacgctgtagcagat
gttcttctcgctagcttctctcggtggattcgggaccccgtttcatcatgttacgagccg
cggctgttagagttggtgagtacgctggcacaccgtgcactgacaactgtcttatttagc
cttgcgaagcttggtggtcgtacggtgaaggtagatggtgactccatcgttgttctgact
ccgaagcacaccattcaagatacggtgagcttcgcacgattcatggtggattccttaaag
gaccagccgatgctcctcctcttgtccctgaaaccgattcgttactggtgcccgtttgtc
attcttgacaagcgggactacgtatttttgtatgtcacgagcgaaggatgcaaatctcta
aaagagaaagatcaggtggtgttagacgagatgctagttgagtactccttcaccatatgg
agtaagctgccaaaaaaggttagggacatcttattggttcgaatagaggggaccttgcgc
gcgatagcgttggcgcgggagagcgtgcttgtcgaggttcaagaggatccaacagtcgtg
ttggcgacaaaaaatgaacaaattcttacgaggatagttggcgtttacaagaagttggtt
gaaggaaaacttcacaccgaacttattgaggaggttcacgacctcacggagcggaaggat
ctccatgaaaaggggttcccagctggtgagacaactctaacaggtgctgcggtcgcactg
gagtacacaaaggtggtttgtcgactattggaactgttccccaacgacggggttttggga
aaggtacgaaataactgtctgaggctgtgtggggtgagtcccttctctccactggcacag
attactgctgatgcagacaccgattgccaccagctgatgtttcaatgtagcttttgtaat
gcagatgttcttcttgatctgagcattcgggagaaacgaatgcgctgcaatggatgcagt
gcccccatattcgcctccgccgtcgagtcttacctcgtacgcaaagtaaacacactggta
atgagctatacaaagcaggactttgtttgtggtaagtgtcacgaggtcacagcaaactct
atcaatcaaacatgttgtgggcctctcgtgggaaaggcaaagccaatccacactcagctt
caggcgctcaaaaaagtcgctgtcattcaggggtttgcgtggttggaggagtgtgttgaa
acagcgcttcaattcagctaa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (59)   
   KEGG ORTHOLOGY (1)   
   RefGene (55)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (77)   

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