KEGG   Tetrahymena thermophila: TTHERM_00624110
Entry
TTHERM_00624110   CDS       T01020                                 
Name
(RefSeq) insulin-degrading enzyme
  KO
K01408  insulysin [EC:3.4.24.56]
Organism
tet  Tetrahymena thermophila
Brite
KEGG Orthology (KO) [BR:tet00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03266 Virion - Herpesvirus
    TTHERM_00624110
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:tet01002]
    TTHERM_00624110
Enzymes [BR:tet01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.56  insulysin
     TTHERM_00624110
Peptidases and inhibitors [BR:tet01002]
 Metallo peptidases
  Family M16: pitrilysin family
   TTHERM_00624110
SSDB
Motif
Pfam: Peptidase_M16_M Peptidase_M16_C Peptidase_M16 DUF6375
Other DBs
NCBI-GeneID: 7822935
NCBI-ProteinID: XP_001022537
TGD: TTHERM_00624110
UniProt: Q240X2
AA seq 1152 aa
MKQNTIVQIDKSPNDDRQYLGFELQNGIKVMVISDSHAEKSAASLDVQVGQLQDPEEYQG
LAHFCEHMLFMGTAKYPLQNEYSQYLSQNGGSDNAYTDILNTNYYFDVKSDAFEEALDRF
SQFFISPLFDETCVEKEINAIENEHQMNVSEDSSRLWGIFKALAKEGTKFRQYGGGCLQT
LQKENIREELLKFYEKYYSAHKMNLVIYGQESIEVLKNLAIKYFSTIQNKEKEQISDEQM
KEMELEKIHPFPREQLCKLVKIIPIKDEDIIEFCWVVEDQQQYCNIKPDDYLTHIFGHEG
KNSLLSLLLDEGLAVELTSYSENCMNLFTIIGFNITLTQRGFFEYKRVCHAVFNYIQVLK
KEVANKEAYEEVKDIEAINFRFLERIAISEYVTKIADGLHWIPMTKILKMRYDFQKYDEI
IIQKLIDSLTLDNIIIYLSSKSFDSQFSKSFNTSQQDLDTVIDSSQVLTKKAQELIETHC
HNHSITHPHGSAAAQKVKKDKELTQEDQASSYDTDQNQLDSHGGESPKLKSPQISARKYS
KSVAKKSYTIEEEFEDFDDENHIYSMLNRKFSYLSQKSETNDGDEEYQDNRSDENFNYAN
AKQNNSKSDDDSFITEKYLGARYLVSEIPEDIKSSYNTEYKPLYSKKKLGLPVKNLFIPK
NFDILPKTDDTSSASKYPIKIFESEMSELYYKQDDTFFICKTYCDLFIFTNDCNQSKTAK
SFVLQEIWLILFENYVNETKYLAQMANIDLKFEQHYTSFKVRIKGYSDKIGVLFEEFLKL
FKSFNPADEGQRLFSTFYERQMSDYDNYYRDAPHSIITDLSKNCLLSTGKFTIKQKIMAL
KEIRLYDIVEFHKQWLSHTRLESLIMGNISKEEAISWIQKAENTMKTLRNIFGILQKSDI
PLIKPNKILPNTTNKLDFLINEKEFNPEETNSCLQSHYQRGPESVESRVMMKLIQNYLSE
PLFNQLRTNEKLGYIVWCWDETFRGVSGFSFLVQSSVCSPMHIQNRLEEFLVNMRKELRQ
LSQEKFENMKHSILIKLTEKPKTLHREFLSMSEEILLHKFVFDRKERIPHILEAITINDL
INDFDNLFFEQKKKLEIHIITNDHKEEQEQLEQERLKQEDIFILQDDTHLKQFCQQIDSL
YYDYSSPVQLQF
NT seq 3459 nt   +upstreamnt  +downstreamnt
atgaagtagaatacgatagtctaaattgataaaagtcctaatgacgatagataatattta
ggttttgaacttcaaaatggtattaaagttatggtaataagtgatagtcatgcagaaaaa
tcagctgcttcacttgatgtttaagttggttaattacaagatccagaagaatattaagga
ttagcacatttttgtgaacacatgctttttatgggcacagcaaaatatcctttataaaac
gaatatagctaatatttaagctaaaatggaggaagtgacaacgcctatactgatatattg
aataccaattactactttgatgttaaatcagatgcatttgaagaagctttagatagattt
agctagttttttatcagtcctctattcgatgagacttgtgtagaaaaagagattaatgca
attgaaaatgaacactaaatgaatgttagtgaagattccagtcgtttatggggaatattt
aaagctctagcaaaggaaggaacaaaatttcgttaatatggaggaggatgcttacaaact
cttcaaaaagaaaatattagagaagaactgcttaaattttatgaaaaatactatagcgct
cataaaatgaatttagtaatatatggtcaggaatcaatagaagtactaaaaaatctggca
ataaaatatttttctacaatacaaaacaaagaaaaagaataaattagtgatgaacagatg
aaagaaatggagttagagaaaattcacccattccctagagagtagctttgcaaattagtt
aaaatcattcccataaaagatgaagatattattgagttctgttgggtagttgaggattaa
taatagtactgtaatataaagccagatgattatttaacgcatatttttggccacgaagga
aaaaattctttgctttctttacttcttgatgaaggattagcagtagaattgacttcttat
tcagaaaattgcatgaatttatttactataattggctttaatatcacattaactcaaaga
ggattctttgaatataaaagggtctgtcatgctgtttttaattatatataagtccttaaa
aaagaagttgccaacaaagaagcatatgaagaggtaaaagatattgaggctataaatttt
cgctttttagagagaatagcaataagtgaatatgtaactaaaattgcagatggacttcat
tggatccctatgaccaaaatcttaaaaatgagatatgatttctaaaagtacgatgaaatt
ataatataaaagctaatagattctctaactttagataatatcataatttatttaagctca
aagagttttgattcacagttttctaaatcctttaacacctctcaataagatttagacact
gtcattgattctagccaggtgctaacaaaaaaagcttaagagttaatagaaactcactgc
cataatcattcaataacacatccacatggttcagctgctgcttaaaaagttaaaaaagat
aaagaattaacttaagaagactaagcttctagttatgatacagatcaaaattaattggat
tctcatggaggagaatctccaaaacttaaaagcccataaatatcagcaagaaaatatagt
aagtctgttgctaaaaaatcttatacaattgaagaagagtttgaagattttgacgatgaa
aatcatatttatagtatgctaaacagaaaatttagctatttatcataaaaatctgaaaca
aatgatggagatgaggaatactaagataatcgtagcgatgaaaattttaattatgctaat
gcaaaatagaataacagcaagagtgacgatgattcattcataactgaaaaatatttagga
gctagatatcttgtaagtgaaattcctgaagatattaaatcttcttataatacagaatat
aagcctctttatagcaaaaaaaaacttggtttacctgttaaaaatttattcattcctaaa
aattttgatatacttcctaagacagatgatacaagtagtgccagtaagtacccaataaag
atttttgaaagtgaaatgagcgaactttattataaataagacgatacgttctttatctgc
aaaacttattgtgacttatttatctttacgaatgattgcaatcaatctaaaacagctaaa
tcatttgtattgcaagaaatttggttaatactttttgaaaactatgttaatgaaactaaa
tatttagctcaaatggctaatatagatttaaaatttgagtagcactacacttcttttaaa
gtaagaataaaaggatatagtgataaaatcggtgtcttgtttgaagagtttttaaagctc
tttaagtcatttaatccagctgatgaaggttaaagattattttcaactttttatgaaaga
taaatgtctgattatgataattactatcgtgatgctcctcactcaattataactgatttg
agtaagaactgtctactttcaacaggaaaatttactattaagtaaaaaataatggcacta
aaagaaataagactttatgacatcgttgaatttcataaatagtggttatcccatactcgt
cttgaaagcttgattatgggaaatattagtaaagaagaggcaatatcttggatataaaaa
gctgaaaacacaatgaaaactttgagaaacatttttggaatactacaaaaatccgacata
cctttgattaaacctaacaaaattcttccaaacaccacaaataaacttgattttctaatc
aacgaaaaagaatttaatcctgaagaaaccaactcatgcttataatcacactactaaaga
ggtccagaatcagtagaatctcgtgttatgatgaagcttatataaaattatttaagtgaa
cctctctttaattaattgcgtactaatgaaaaactaggttatatagtctggtgctgggat
gagacatttagaggagtgagtggattttcattcttagttcaatcctccgtttgctcacct
atgcatatctaaaatagacttgaagagtttttagtaaatatgagaaaagaattaagataa
ctttcccaagaaaaatttgaaaatatgaaacattccattctaatcaaactcacagaaaag
cctaaaaccttacatagagaatttctatcaatgtctgaagagattttgttgcataaattt
gtatttgatagaaaggaaagaataccacatattttagaagcaatcactattaatgatctt
attaatgattttgataacttattttttgagtaaaagaaaaaattagaaattcacataata
acaaatgatcataaagaagaacaagaataattagaacaagaacgtctaaaataagaagac
atctttattttataggatgacactcacctgaaatagttctgctagtaaattgatagtctt
tattatgattattcaagtccagtatagttgcaattttga

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Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (91)   
   KEGG ORTHOLOGY (1)   
   RefGene (86)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   TGD (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (103)   

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