KEGG T03005: TES1

Thermococcus paralvinellae: TES1_0593

Entry

TES1_0593         CDS       T03005

Name

(GenBank) phosphomethylpyrimidine kinase

K21219

hydroxymethylpyrimidine kinase / phosphomethylpyrimidine kinase / thiamine-phosphate diphosphorylase [EC:2.7.1.49 2.7.4.7 2.5.1.3]

Organism

ths Thermococcus paralvinellae

Pathway

ths00730

Thiamine metabolism

ths01100

Metabolic pathways

ths01240

Biosynthesis of cofactors

Module

ths_M00896

Thiamine biosynthesis, archaea, AIR (+ NAD+) => TMP/TPP

ths_M00899

Thiamine salvage pathway, HMP/HET => TMP

Brite

KEGG Orthology (KO) [BR:ths00001]
09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00730 Thiamine metabolism
    TES1_0593
Enzymes [BR:ths01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.3  thiamine phosphate synthase
     TES1_0593
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.49  hydroxymethylpyrimidine kinase
     TES1_0593
   2.7.4  Phosphotransferases with a phosphate group as acceptor
    2.7.4.7  phosphooxymethylpyrimidine kinase
     TES1_0593

SSDB

Motif

Pfam:

Phos_pyr_kin ThiP_synth PfkB HK Carb_kinase

Other DBs

NCBI-ProteinID:

AHF79983

UniProt:

W0I6H1

Position

551894..553252

AA seq 452 aa
MDARKYVKTALTIAGSDSGGGAGIEADLKTFSAFGVHGLVAIISVTAQNTQEVRAIYDVS
PEVVAKQIEAVADDIGVDAAKTGMLSNAEIIKAVARTVKKYEFPLVVDPVMIAKSGAPLL
REDAMDALIEYIIPLATLVTPNKPEAEKLSGIKIETLEDAKKAAKIIVEELGAKAAIVKG
GHLNLSEAVDVLYHAGKFREYRAPFVEGCTHGTGCSFSAAITANLAKGKGLEEAIKVAKE
FITMGIFYGARIGKGHCPVNQNVWIEIPAEKWRVYESLTKAVRELERIGDRILPHVPEVG
MNFVYALPRLYARTPKDVAGVKGRIVRFGNTVKAVGSIEFGASSHLARAVLKFMEFYPEI
RSALNLRYSRGLIDRAQKNGFKVSFYDRREEPEEIKAKEGATIPWGIETAIKRLSGRPDI
IYHLGDWEKEAMVLIFGESPEDVLRKLKMLTE

NT seq 1359 nt +upstreamnt +downstreamnt
gtggatgctagaaagtatgtaaaaacagctctaacgatagcagggagcgatagtggggga
ggcgctggcattgaggcggatttaaaaactttttcagcctttggagttcatggcttggtg
gcaataatctcagtcacagctcaaaacactcaagaggttagagcgatttatgatgtatct
ccagaggttgtggcaaagcagattgaagcagttgcagatgacattggggttgatgctgct
aagacaggaatgctgagcaacgctgaaataataaaagctgttgcaaggactgtgaagaag
tatgaattcccacttgtagttgatccagtgatgatcgctaagagcggagctcctcttttg
agagaagatgcaatggatgctcttatcgaatatataatccccctagctacacttgtaacg
ccaaataagccagaagctgaaaagctgagcggtattaaaattgaaactctcgaggatgca
aaaaaggcggcaaagattattgttgaagagctgggagcgaaagcggcaatagtgaaaggg
ggacatctaaacctcagtgaagctgttgatgtgctttatcatgctggaaaatttagggaa
tacagggctccttttgttgaaggctgtacccatggaactggttgctcgttctcagcagcg
ataactgcaaacttagcaaaagggaaaggcttagaggaagcaattaaggttgcaaaagag
ttcataacaatgggcatcttttatggtgcaagaattgggaaaggacactgcccagttaat
cagaatgtttggattgaaattccagcggagaaatggcgggtctatgaaagcctaacaaaa
gctgtaagggagctcgagagaattggagacagaattttaccccatgtaccagaagttggc
atgaactttgtttatgcattaccaaggctttatgcaaggactcctaaagatgtggctgga
gttaaagggcgtattgtaagatttggaaatacagtaaaagcagttggcagtatagaattc
ggggcatcaagccatctagcaagagcagttctaaagttcatggaattttacccagagatc
agaagtgcccttaatttgagatacagcagaggcttaattgatagagctcaaaaaaatggg
ttcaaagtttcattctatgatagaagagaagaaccagaggagataaaagctaaagaaggt
gcaacaattccttggggcattgaaacagcaataaaaagactaagtggaagaccagacata
atatatcaccttggtgattgggaaaaggaagcaatggtgctgatatttggggagtctcca
gaggacgtgctgagaaagcttaagatgctaaccgaataa

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