KEGG   Candidate division TM6 bacterium GW2011_GWF2_28_16: US01_C0001G0145
Entry
US01_C0001G0145   CDS       T04457                                 
Name
(GenBank) ddl, D-alanyl-alanine synthetase A, D-alanine-D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
tmg  Candidate division TM6 bacterium GW2011_GWF2_28_16
Pathway
tmg00470  D-Amino acid metabolism
tmg00550  Peptidoglycan biosynthesis
tmg01100  Metabolic pathways
tmg01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:tmg00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    US01_C0001G0145
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    US01_C0001G0145
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    US01_C0001G0145
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:tmg01011]
    US01_C0001G0145
Enzymes [BR:tmg01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     US01_C0001G0145
Peptidoglycan biosynthesis and degradation proteins [BR:tmg01011]
 Precursor biosynthesis
  Amino acid ligase
   US01_C0001G0145
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATPgrasp_ST ATP-grasp_4 ATP-grasp_3 GARS_A
Other DBs
NCBI-ProteinID: AKM81105
UniProt: A0A0G4B0L3
Position
168353..169477
AA seq 374 aa
MAKINLALICGGKSAEHEVSLISAKNVIVALDFNKYNLFLFAVTKDGAFRFYADKQNFLD
NQDNPDIVSLKESGFSEVAWLSADQRGQAMLLGDKEQFLQLDVVFPIMHGSFAEDGKMQG
FLEMLDLPYVGPDVLASAISMDKEITKKLSVAAGVKISRYLSFDTNTKEKINFQEIKSAL
SMPVFIKPANAGSSVGISKADDEKSFMVAIDQAFHFDHKILIEEAIVGRELECSVLGNRE
KLIAGEVGEIIPSAKHGFYSYEAKYLDESGAALLIPAPLAPAKKKEIQELSKKIFAACQC
EGMARVDFFMTKNGEVVFNEINTIPGFTKISMYPKLMMSETGMTYGELIDELINLAIKRY
SRNSKILFVKKMVK
NT seq 1125 nt   +upstreamnt  +downstreamnt
atggcaaaaattaatctagctctaatttgtggtggtaaatctgcagaacacgaagtgtct
ctgatttcggctaaaaacgtgatcgttgctctagattttaataaatataatctttttctt
tttgcggtgactaaagacggagcttttcgtttttatgctgataagcagaattttttagac
aatcaagataatccagacatagtttccctcaaggaaagtggtttttctgaagttgcttgg
cttagtgctgatcagcgtgggcaagcgatgttgcttggcgataaagagcaatttttacaa
ttagatgtggtttttccaattatgcacggttcctttgctgaagatggcaaaatgcagggc
tttttggaaatgttggatttgccttatgttggcccagatgttttagcttcggcaatttct
atggacaaggaaattactaaaaaattatctgtagcagcaggtgtcaaaatttctagatat
ttatcttttgatactaacactaaagaaaaaatcaattttcaagaaatcaaatcagctcta
tctatgcctgtttttatcaagccagctaatgccggctcttctgtgggaattagtaaagct
gatgatgaaaaatcttttatggttgctatcgatcaggctttccattttgatcataaaatt
ttaattgaagaagcaattgttggcagagagttggagtgctccgttttaggaaacagagaa
aaattaattgctggtgaagtgggtgaaattattccaagcgctaagcatggcttttattct
tatgaggcaaaatatcttgatgaatcaggcgcagctctacttattccagctccgctcgca
ccagccaagaaaaaagaaatccaagaattatctaagaaaatttttgcagcttgccaatgt
gaaggcatggcgagagtagattttttcatgacaaaaaatggtgaagttgtttttaatgaa
atcaacaccattcctggatttaccaagattagtatgtatcctaaattaatgatgagtgaa
acaggtatgacttatggagaattaattgatgagttgattaatttagctataaagcgctac
tcaagaaattctaagattttgtttgtgaaaaaaatggtaaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (6)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (8)   
   Pfam (8)   
All databases (30)   

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