KEGG   Thermaerobacter marianensis: Tmar_0273
Entry
Tmar_0273         CDS       T01388                                 
Name
(GenBank) FolC bifunctional protein
  KO
K11754  dihydrofolate synthase / folylpolyglutamate synthase [EC:6.3.2.12 6.3.2.17]
Organism
tmr  Thermaerobacter marianensis
Pathway
tmr00790  Folate biosynthesis
tmr01100  Metabolic pathways
tmr01240  Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:tmr00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Tmar_0273
Enzymes [BR:tmr01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.12  dihydrofolate synthase
     Tmar_0273
    6.3.2.17  tetrahydrofolate synthase
     Tmar_0273
SSDB
Motif
Pfam: Mur_ligase_C Mur_ligase_M AAA_16
Other DBs
NCBI-ProteinID: ADU50398
UniProt: E6SMD8
Position
315590..317263
AA seq 557 aa
MQQRREGRQDGTRGPAATGLGSAGPAIPETDGGAAGTGGTAGTAARAAGRSANGAGGAGA
TAGNGSGSASGAAGTARTGAGIASTGAGAARTGAGQAAVEYLQGLSRFGMRLGLERIRQL
LQRLGHPEEGLPPVYHITGTNGKGSTACILEAVLRSAGYRTALFTSPHLVHYEERFVFDG
RPVTGAELAAAVERARAAAGAMAAEGEAPTEFEVATAVFLLLVQMRQPDAVVLEVGLGGR
YDATNAVPRPVVSVVTNVALDHTDRLGRTVEEIAYDKVGIARPGVPLVTGALDPGALAVL
RREAARVGAPLWEVRPDEPGPQGPGPAAAARYRLRSTGPDGSRWDYRCGAVTPAGQGGLP
GTPVRWDDLPLALLGPHQVANAAVAVTALLAAAAAGRGLPVTREVVERGLAAARWPGRME
RLAWRGREIWLDGAHNPAGMAALARTAATLWPGRQALLVIGMLDDKDVEAAAAAIAPTVA
RAVVTEPPSPRAAPARRVAAALEACGVPVTVEREPMAALDRALGEAAPGQPVLVAGSLYL
VGAVRGRVLEPAAAPGR
NT seq 1674 nt   +upstreamnt  +downstreamnt
gtgcaacagcggcgcgaaggaaggcaggacggaacgcgcgggccggcggccaccgggctc
ggatccgccggcccggccattcccgaaaccgacggcggggcggccgggacgggcgggacg
gccggcaccgcggcccgggcagccggccgttcggcgaacggggcgggcggtgccggcgcc
acggccggaaacgggtcggggtctgccagcggcgcggccgggacggcccgcaccggcgcc
gggatcgcctcgaccggtgccggcgccgcccgtaccggcgccggtcaggccgcggtggaa
tacctgcaggggctgagccgcttcggcatgcggctgggcctggagcgcatccggcagctg
ctgcagcggctcggccaccccgaggaagggttgccgcccgtctaccacatcacgggaacc
aacggcaagggctcgaccgcgtgcatcctcgaggccgtgctccggtccgccggctaccgc
acggccctcttcacgtcgccccacctggtccactacgaggaacggttcgtcttcgacggc
cggcccgtcaccggggccgaactggccgccgccgtcgagcgggcgcgggccgcggccggc
gccatggcggccgagggcgaggcgcccacggagttcgaggtggcgacggccgtgttcctc
ctgctggtccagatgcggcagcccgacgccgtggtgctggaggtggggctgggcggccgc
tacgacgcgaccaacgccgtgccccggcccgtggtgtcggtggtgaccaacgtggccttg
gaccacaccgaccggctgggccgcacggtggaggagatcgcctacgacaaggtgggcatc
gcccggcccggcgtgccgctggtcacgggggccctggaccccggcgccctggcggtgctg
cggcgcgaggcggcacgggtgggagcgcccttgtgggaggtccggccggacgaacccggc
ccccaggggcctgggccggcggccgccgcccgctaccgcctgcggtccacggggccggac
gggtcgcgttgggactaccgctgcggggcggtgacgccggccggacaagggggcctgccc
ggcacgcccgtccgctgggacgaccttcccctggccctcctcgggccccaccaggtggcc
aatgcggccgtggcggtgaccgccctgctggccgcggcagcggccggccggggcttgccc
gtgacccgggaggtggtggagcgcggcctggcggcggcccgctggcccgggcggatggag
cggctggcctggcggggccgggagatctggctggacggggcccacaacccggcgggcatg
gccgccctggcccggacggcggccaccctctggcccggccggcaagccctgctggtcatc
gggatgctggacgacaaggacgtggaggcggcggcggcggccattgcccccacggtggcc
cgggcggtggtgacggagccgccgtcgccccgggcggcgccggcccggcgggtggcggcg
gccctggaggcctgcggggtgccggtcacggtggaacgggagcccatggccgccctggac
cgtgccctgggggaggcggcgccgggccagcccgtgctggtggcggggagcctgtacctg
gtcggcgctgtgcgcggccgggtgctggagccggccgctgcgcccggccgctga

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