KEGG   Thermotoga maritima Tma200: THMC_1274
Entry
THMC_1274         CDS       T03901                                 
Name
(GenBank) IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
tmx  Thermotoga maritima Tma200
Pathway
tmx00230  Purine metabolism
tmx00670  One carbon pool by folate
tmx01100  Metabolic pathways
tmx01110  Biosynthesis of secondary metabolites
Module
tmx_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:tmx00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    THMC_1274
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    THMC_1274
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tmx04147]
    THMC_1274
Enzymes [BR:tmx01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     THMC_1274
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     THMC_1274
Exosome [BR:tmx04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   THMC_1274
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS CoA_binding_2
Other DBs
NCBI-ProteinID: AKE27158
Position
1274175..1275533
AA seq 452 aa
MKRILVSLYEKEKYLDILRELHEKGWEIWASSGTAKFLKSNGIEANDVSTITGFENLLGG
LVKTLHPEIFAGILGPEPRWDVVFVDLYPPPDIDIGGVALLRAAAKNWKKVKPAFDMETL
KLAIEIDDEETRKYLAGMTFAFTSVYDSIRANQFVEGISLAFKREDLQLRYGENPHEKAF
VYGKPAFEILHEGKTISFNNILDAENAWFMAKNLPRMGAVVVKHQSPCGAAIGEDKVEIV
KKAIEADDESSFGGILAVNFEMDEEVAKSLKKYLEVIVAPSFTQEAIEVLSKKKVRLLKP
GDYASWAGKMAFGSLVLSERKYPEGNFELVVGEPLSEKELEDLEFAYRVVEGAKSNAVLI
AKDGVTVGIGSGQPSRKRAAWIATVMAGEKAKGAVAASDAFFPFPDSLEILAQAGVKAVV
APLGSIRDEEVIEKARELGITFYKAPSRVFRH
NT seq 1359 nt   +upstreamnt  +downstreamnt
ttgaagaggatattggttagtctctacgagaaagaaaaatatctggatattctgagagaa
ctccacgaaaaaggctgggagatctgggcgagctccggcaccgccaagtttttgaaatca
aacggaatagaagcaaacgacgtgagcaccataacgggtttcgagaatctcctcggaggg
ctcgtgaagaccctccacccggagatattcgccggcatcctcggaccggaacccagatgg
gatgtggtctttgtggacctatatccacccccagacatcgacataggaggagtcgctctt
cttcgagcagctgccaaaaactggaaaaaggtgaaacccgctttcgacatggaaacactc
aaactcgcgattgagatagacgacgaagagacgagaaagtacctcgctggaatgaccttt
gcgttcaccagtgtgtacgattcgataagggccaaccagtttgtcgagggtatttctctc
gccttcaagagggaagatcttcagctgaggtacggagagaaccctcacgaaaaagcgttt
gtgtatggaaaaccagcttttgagattctgcacgaaggaaagacaatctcattcaacaac
atcttagacgcggaaaacgcgtggttcatggcgaagaacctgccgaggatgggtgcggtt
gtggtgaaacaccaatctccctgtggtgctgcgataggagaagacaaagtggaaatcgtg
aagaaggccatcgaggcggacgacgaatccagttttggagggatcctggccgtgaacttc
gaaatggacgaagaagttgcgaagtcattgaaaaagtacctcgaggtgatcgtggcacct
tccttcacacaggaagcgatcgaggttctctctaagaaaaaagtgcgtctcttgaagcct
ggggattacgcttcgtgggctggaaagatggcattcggttctctcgtcctgagtgaaaga
aagtaccccgaagggaattttgaactggtagttggagagcctctctcggaaaaagagctt
gaggatctggaattcgcttaccgtgttgtggaaggagcgaaatccaacgctgttctcata
gcaaaagacggtgtaactgtgggaatagggagcgggcagccttcgagaaagagagctgcc
tggatcgccaccgtgatggcaggagaaaaagcgaagggagcggttgcggcttccgatgcg
ttcttcccgttcccggactcgctcgaaatactcgctcaggctggtgtgaaagcggtggtc
gctcctctcggatccataagagacgaagaagtgatcgaaaaagccagagaacttggaatc
acgttctacaaagctccgagcagggttttcaggcactga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (25)   

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