KEGG   Thermodesulfobacterium geofontis: TOPB45_0227
Entry
TOPB45_0227       CDS       T01547                                 
Name
(GenBank) transporter, hydrophobe/amphiphile efflux-1 (HAE1) family
  KO
K18138  multidrug efflux pump
Organism
top  Thermodesulfobacterium geofontis
Pathway
top01501  beta-Lactam resistance
top01503  Cationic antimicrobial peptide (CAMP) resistance
Brite
KEGG Orthology (KO) [BR:top00001]
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01501 beta-Lactam resistance
    TOPB45_0227
   01503 Cationic antimicrobial peptide (CAMP) resistance
    TOPB45_0227
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:top02000]
    TOPB45_0227
   01504 Antimicrobial resistance genes [BR:top01504]
    TOPB45_0227
Transporters [BR:top02000]
 Other transporters
  Electrochemical potential-driven transporters [TC:2]
   TOPB45_0227
Antimicrobial resistance genes [BR:top01504]
 Gene sets
  Multipdrug resistance modules
   Multidrug resistance, efflux pump MexAB-OprM [MD:M00718]
    TOPB45_0227
SSDB
Motif
Pfam: ACR_tran SecD_SecF COX2-transmemb MMPL DUF3479
Other DBs
NCBI-ProteinID: AEH22342
UniProt: F8C2W3
Position
214960..218094
AA seq 1044 aa
MISQFFIRRPRVALVSAIAVVLLGLISLSVLPVKEYPALTPPQIVVTARYPGADSETIAK
TVAAPLEEAINGVDGMLYMVSSSTSAGVYTLNVYFEVGWDPNVAKMDVNNRVQIALPRLP
EEVRRLGVEVRERSPDILKVVAFYSEGGQRDVVELANFLLINVIDELKRVPGVADAILVD
PKVYSIRVWLLPDKLSMYGLTPLEIYQAISQQNQQFTAGALADEPTTERPFFTYVLRGSD
RFSSAKQFEEILVKVLPDGSTLKLKDVARVELTSEQFNRNSFFKKQKVLPVPIFLTSRAN
ALEVSKLIDEKLKELSKTWPPDIKYYFPYNPTVFVKESIKEVWITFGLAILFVVIVTYFF
LGGLAPTIVPTLAIPVSIFGAFIVMYVLGFSVNLLTLFGLILAIGLVVDDAIIVVENVER
HMEEGLPVKEATLKAMEELTSPLIAIVLVLSAVFIPASLVGGFIGRFYQQFAVAIASSVL
ISGMTALVFSPVLCTLLLRERELHKRPIYPVYLFQLIFNRARESYVERIKFLLKRPAIFV
LLFLLILPLTYVLIKRLPTALVPTEDKGALFLIGNLPPGSSLKRTEEVLSKIEDIFMKNP
YIDRYVAISGFDLQGFTYSTDSLGGFIGLIDWSKRTKKEETSFALTQRINKELSQIREAV
LFVVSPPAIMGFGRVGGFDLYLEDRTGGDIRQMFEVAQGFINKLRERKELTLVRTTFNPS
NPYFEVIVDRTKAEAYGVSVNDVYKTLSMTLGASYVNDFNLFDRVYRVYLQAEFDYRKAF
DDLSKVYVKNKNGVPIPVANLVEIKPLSRPQLLERHNQFKAVRILGEPASGYTTGDAIRV
VEKVAKATLPPGYTIGWVGQSLQEVLSQQKGYVVLAMAVLFVYLILVALYESWLAPIAVI
LSIPFALLGASLTLNLLKLPNDVYFQVGLVTLVGLSAKNAILVVEFAEERIRRGMDIISA
ILEASYLRFRPIVMTSFAFIAGAIPLALSTGAGAMSRHVIGWTVVGGMLFATLLGTLFIP
LLYYVIKALSLKSLKILKRGKENA
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgatatcccagttttttattcgcagaccaagggtagctttagtttcagccattgcagtc
gtgcttttagggttgatttcactttctgtcttaccagttaaggagtatccagcccttact
ccaccccagatagtggttactgcaaggtatccgggagctgattctgaaacgattgccaaa
acggttgctgcccctcttgaagaagcgataaacggcgttgatggtatgctctacatggtt
tcttcttcaacctcagcgggagtttacaccttgaatgtttactttgaggttggctgggac
cctaatgtagcgaaaatggatgtaaacaaccgcgttcagattgcgctgccgaggcttcct
gaggaggtaagaaggcttggcgttgaagttcgggaaagaagcccggatatacttaaagtt
gtagccttctactctgagggagggcagagggatgtagtcgaacttgctaacttccttctc
atcaacgtaatagacgagttaaaaagagttcccggtgtagccgatgccattctcgttgac
cctaaggtatattctatcagggtgtggcttttgcctgataaactttctatgtatgggtta
acgccccttgaaatctatcaggcaatttctcaacagaaccagcagtttaccgctggtgcc
ttggcggatgagccaaccacagagagacctttctttacctatgttcttagaggtagcgat
aggttctcctcggctaaacagtttgaagagatactggttaaagttttgcctgatggttcg
accttaaagcttaaagatgtggcaagggttgagctaacctctgagcagtttaaccgcaat
tccttctttaagaagcaaaaggttttacctgttcccatctttcttacaagcagagcaaac
gcccttgaggtttcaaagcttattgacgaaaagctaaaggagttaagcaaaacctggccc
ccagacataaagtactattttccctacaaccctacggtttttgttaaagaatcgatcaag
gaagtgtggataacctttggacttgccatcctttttgtagtcattgtgacctactttttc
cttggggggcttgctccaacaatcgttccaaccttagccattccagtctccatctttggt
gcctttatcgttatgtatgttcttggcttctcagtaaaccttcttaccctgtttgggttg
atcttagccattgggcttgtggttgacgatgccatcatcgtcgttgaaaacgtggaaaga
catatggaagaggggctaccggtaaaagaagcaactctaaaagccatggaagagcttacc
tcaccgcttatcgccatcgttcttgtgctttctgccgtctttataccggcaagccttgtt
ggcggttttatcggaaggttctatcaacagtttgccgtagctatagcaagctcggtgctt
atttcaggtatgactgccttggtttttagcccagtcctctgtacccttctccttagggaa
agggagctacacaaacgccccatctatccggtttatctttttcagcttatctttaaccga
gcaagggaaagctatgtagagcggataaagtttctcttaaagagacccgcaatctttgtc
ttgctattccttttaattctacctctaacctatgttttaataaaaaggctacctactgct
cttgtccctactgaggataaaggggctctttttttgatcgggaaccttccaccaggtagt
tcccttaagcggacggaggaggttctatccaagattgaggacatctttatgaagaaccct
tacattgaccgctacgttgccatctcgggctttgaccttcagggctttacctattctaca
gattctttaggtggctttataggattgatagattggagcaaaaggactaagaaggaagag
acctcttttgcccttacccaaaggataaacaaagagctttctcagattagggaagccgtg
ctttttgtggtaagtcctccggctattatggggtttggaagagtaggagggtttgacctt
tatcttgaggatagaaccggtggtgatataaggcagatgtttgaggttgctcaaggtttt
atcaacaagcttagagaaagaaaggagctaaccttagttagaacaaccttcaacccctca
aacccttactttgaggtaatagtcgaccgaacgaaggctgaagcctacggggtctcggtt
aacgatgtatataagactttgagcatgaccttaggggcaagctatgtgaacgattttaac
ctctttgacagggtttaccgagtataccttcaagcagaattcgattatcgtaaagcattt
gatgaccttagcaaggtctatgttaaaaataaaaatggcgttcccatccccgttgctaac
cttgtagagattaagccccttagcagaccgcagctccttgagaggcataatcagtttaaa
gcggtgcgcatccttggtgagcctgcttctggctacacaaccggcgatgccataagggtg
gttgagaaagtagctaaggctacccttccccctgggtataccatcggttgggtggggcaa
agcttgcaggaggttttatcccagcagaagggttacgtcgtccttgccatggctgtcctc
tttgtctatcttatccttgtagctctttatgaaagctggcttgctccgattgcggttatc
ctctccattcccttcgcccttctcggggcaagcttaaccttaaaccttttgaagcttccc
aatgatgtgtattttcaggttgggcttgtgaccttggtaggtctttccgcaaagaacgct
atccttgttgtggagtttgccgaagagcgtatcagacgaggtatggacatcatctcagcc
attcttgaagcttcctatcttaggtttagaccaatagttatgacctcttttgcctttatc
gctggagccatacccttagcgctaagcacaggagctggcgccatgagtagacatgttatc
ggttggactgttgtcggaggtatgctctttgcaacccttttgggaaccctctttatcccg
cttctctactatgtgataaaggctttgagcttaaagagcttaaaaatccttaaaagaggc
aaagaaaatgcgtaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (19)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (5)   
   Pfam (5)   
All databases (35)   

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