KEGG   Theileria orientalis: TOT_040000412
Entry
TOT_040000412     CDS       T03460                                 
Name
(RefSeq) bifunctional dihydrofolate reductase/thymidilate synthase
  KO
K13998  dihydrofolate reductase / thymidylate synthase [EC:1.5.1.3 2.1.1.45]
Organism
tot  Theileria orientalis
Pathway
tot00240  Pyrimidine metabolism
tot00670  One carbon pool by folate
tot00790  Folate biosynthesis
tot01100  Metabolic pathways
tot01232  Nucleotide metabolism
tot01240  Biosynthesis of cofactors
Module
tot_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:tot00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    TOT_040000412
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    TOT_040000412
   00670 One carbon pool by folate
    TOT_040000412
Enzymes [BR:tot01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     TOT_040000412
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.45  thymidylate synthase
     TOT_040000412
SSDB
Motif
Pfam: Thymidylat_synt DHFR_1
Other DBs
NCBI-GeneID: 20716476
NCBI-ProteinID: XP_009692337
UniProt: J4C4E3
Position
4:join(904519..904793,904825..904919,904951..905331,905363..905456,905488..905633,905719..905785,905819..905913,905974..906134,906177..906401)
AA seq 512 aa
MGNDYTDLPPIKILAGITPDNGIGNTNGLPWPHIKRDFLYMFRLTTYVDPSVKQNNSEIQ
NVVVIGRKTYDSLPPNTFPFKNRISVVISRTLSEVPGGFVFDSVPKALMYIKDNLNYYKI
FILGGSFIYNEVINMPVLDTLYITRVNKKYPCDVFFPKIPEDYVITGISKTFTNGDTTYD
FVTYERKDQLREEPDHRTFHELLLTGEKFANKPPLYKACPNLKVRYSQELQYLDILADIL
NNGVKKTNRTGVDCFAKFGYQMRFDLSESFPLLTTKKVFLRGIIEELIWFIRGSTNGNDL
LKKNVKIWELNGARGFLDALGFYDREEHDLGPVYGFQWRHFGAKYVDMHTDYNGQGIDQL
SILIDKIKNKPNDRRLIVCSWNVADLSKMALPPCHLLFQFFVADGKLSCMMHQRSCDMGL
GVPFNIASYSLLTYMIAQICDLEPGEFVHNLGDAHIYCNHVDAVKEQISRVPYPFPSLKL
NKEIKRIEDFTLEDIKVENYISHPAIKMDMAA
NT seq 1539 nt   +upstreamnt  +downstreamnt
atgggtaacgattacaccgatttgccacctattaaaatcttggccggtattacaccggat
aatggaatcggcaatactaatggcttgccatggccacacatcaagagggatttcctttat
atgtttaggttgactacatatgttgaccctagtgttaagcaaaacaactcggaaatacaa
aatgtagtcgttattggaagaaaaacctacgacagtcttcctcctaacacatttcctttt
aaaaacaggattagcgtggtcatttcaagaacactaagcgaggtacccggaggatttgtg
ttcgactccgttcctaaagcactgatgtatatcaaagacaatttaaactactataaaata
ttcatcctgggcggaagtttcatttacaatgaggttatcaacatgccggttcttgatact
ctgtatataaccagggtcaacaagaagtatccgtgcgacgtgttcttcccgaagattccc
gaggattacgtaatcacaggaatcagtaagacttttacaaacggggacacaacatacgac
ttcgtgacctatgaaaggaaggatcaactaagagaagagccggatcatagaacctttcac
gaacttcttctgaccggggaaaagtttgcaaataagccacctttgtataaggcgtgtcca
aacttgaaagttagatacagccaggaactacagtatcttgacattctggctgatatacta
aacaacggagtgaaaaagaccaacagaacaggggtggattgctttgccaagtttggatac
cagatgagattcgacttatcagagtcgtttccactattgacaacgaagaaggtctttcta
agaggaataattgaggaactcatatggttcattcggggaagcaccaacggaaacgatctg
ctaaaaaagaacgttaaaatatgggagttgaatggagcaagaggattcctggacgcatta
gggttttatgacagagaggaacacgatttagggcctgtttacggattccagtggagacat
tttggtgctaaatacgtggatatgcacacggactacaatggccagggaatcgaccagttg
tcaatattgatcgataaaataaagaataagcccaatgacaggagacttatagtttgctcc
tggaacgttgcagatttgtcgaaaatggcactgccgccttgtcatttgttgttccagttc
ttcgtagcggacggaaagctgtcgtgtatgatgcatcaaaggtcatgtgatatgggtctg
ggagtcccatttaacattgcctcgtactctctactgacatatatgatagcccaaatttgc
gatcttgaacctggagagtttgtccacaatctgggcgacgcacatatatactgtaaccac
gttgatgcggtcaaggagcagatatcgagagtaccgtacccatttccgagtttaaaatta
aataaggaaattaagaggatagaagatttcacactggaagacattaaagtggaaaattac
atatcacacccagccataaaaatggatatggcagcataa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (9)   
   KEGG PATHWAY (6)   
   KEGG MODULE (3)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (9)   
   KEGG ENZYME (2)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (41)   

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