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Database: UniProt/TrEMBL
Entry: A0A0F6AYS3_SALT1
LinkDB: A0A0F6AYS3_SALT1
Original site: A0A0F6AYS3_SALT1 
ID   A0A0F6AYS3_SALT1        Unreviewed;       346 AA.
AC   A0A0F6AYS3;
DT   24-JUN-2015, integrated into UniProtKB/TrEMBL.
DT   24-JUN-2015, sequence version 1.
DT   22-NOV-2017, entry version 12.
DE   RecName: Full=Aldose 1-epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE            EC=5.1.3.3 {ECO:0000256|PIRNR:PIRNR005096};
DE   AltName: Full=Galactose mutarotase {ECO:0000256|PIRNR:PIRNR005096};
GN   Name=galM {ECO:0000313|EMBL:ACY87396.1};
GN   OrderedLocusNames=STM14_0898 {ECO:0000313|EMBL:ACY87396.1};
OS   Salmonella typhimurium (strain 14028s / SGSC 2262).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=588858 {ECO:0000313|EMBL:ACY87396.1, ECO:0000313|Proteomes:UP000002695};
RN   [1] {ECO:0000313|EMBL:ACY87396.1, ECO:0000313|Proteomes:UP000002695}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=14028s / SGSC 2262 {ECO:0000313|Proteomes:UP000002695};
RX   PubMed=19897643; DOI=10.1128/JB.01233-09;
RA   Jarvik T., Smillie C., Groisman E.A., Ochman H.;
RT   "Short-term signatures of evolutionary change in the Salmonella
RT   enterica serovar typhimurium 14028 genome.";
RL   J. Bacteriol. 192:560-567(2010).
CC   -!- FUNCTION: Converts alpha-aldose to the beta-anomer.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- CATALYTIC ACTIVITY: Alpha-D-glucose = beta-D-glucose.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
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DR   EMBL; CP001363; ACY87396.1; -; Genomic_DNA.
DR   RefSeq; WP_000931428.1; NC_016856.1.
DR   ProteinModelPortal; A0A0F6AYS3; -.
DR   EnsemblBacteria; ACY87396; ACY87396; STM14_0898.
DR   KEGG; seo:STM14_0898; -.
DR   PATRIC; fig|588858.6.peg.935; -.
DR   KO; K01785; -.
DR   OMA; ATWLSCK; -.
DR   UniPathway; UPA00242; -.
DR   Proteomes; UP000002695; Chromosome.
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR018052; Ald1_epimerase_CS.
DR   InterPro; IPR013458; Ald_epimerase_bac.
DR   InterPro; IPR015443; Aldose_1-epimerase.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   PIRSF; PIRSF005096; GALM; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
DR   TIGRFAMs; TIGR02636; galM_Leloir; 1.
DR   PROSITE; PS00545; ALDOSE_1_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002695};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR005096}.
FT   ACT_SITE    175    175       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   ACT_SITE    309    309       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   BINDING     245    245       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR005096-2}.
SQ   SEQUENCE   346 AA;  38547 MW;  990137870BC8F60A CRC64;
     MLNETPALAP DGQPYRLLTL RNSAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE
     HYPEQTSFLG ASIGRYANRI ANSRYTFAGE TVQLSPSQGE NQLHGGPEGF DKRRWQIVNQ
     NDRQVLFALT SDDGDQGFPG HLCATAQYRL TDDNRISITY RATVDKPCPV NLTNHVYFNL
     DGDRTDVRQH KLQILADEYL PVDESGIPRQ GLKSVANTSF DFRMPKVIAS EFLADDDQRK
     VKGYDHAFLL QTQGDGKKPA ARLWSQDGKL QMMVYTTAPA LQFYSGNYLA GTPSRGPEPY
     ADWQGLALES ELLPDSPNHP EWPQPDCILR PGEEYASLTE YQFIPF
//
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