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Database: UniProt/TrEMBL
Entry: A0A0H3ECD2_BIFBP
LinkDB: A0A0H3ECD2_BIFBP
Original site: A0A0H3ECD2_BIFBP 
ID   A0A0H3ECD2_BIFBP        Unreviewed;       834 AA.
AC   A0A0H3ECD2;
DT   16-SEP-2015, integrated into UniProtKB/TrEMBL.
DT   16-SEP-2015, sequence version 1.
DT   28-FEB-2018, entry version 15.
DE   SubName: Full=Exo-alpha-sialidase {ECO:0000313|EMBL:ADP36807.1};
DE            EC=3.2.1.18 {ECO:0000313|EMBL:ADP36807.1};
GN   OrderedLocusNames=BBPR_1794 {ECO:0000313|EMBL:ADP36807.1};
OS   Bifidobacterium bifidum (strain PRL2010).
OC   Bacteria; Actinobacteria; Bifidobacteriales; Bifidobacteriaceae;
OC   Bifidobacterium.
OX   NCBI_TaxID=702459 {ECO:0000313|EMBL:ADP36807.1, ECO:0000313|Proteomes:UP000002312};
RN   [1] {ECO:0000313|EMBL:ADP36807.1, ECO:0000313|Proteomes:UP000002312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PRL2010 {ECO:0000313|EMBL:ADP36807.1,
RC   ECO:0000313|Proteomes:UP000002312};
RX   PubMed=20974960; DOI=10.1073/pnas.1011100107;
RA   Turroni F., Bottacini F., Foroni E., Mulder I., Kim J.H., Zomer A.,
RA   Sanchez B., Bidossi A., Ferrarini A., Giubellini V., Delledonne M.,
RA   Henrissat B., Coutinho P., Oggioni M., Fitzgerald G.F., Mills D.,
RA   Margolles A., Kelly D., van Sinderen D., Ventura M.;
RT   "Genome analysis of Bifidobacterium bifidum PRL2010 reveals metabolic
RT   pathways for host-derived glycan foraging.";
RL   Proc. Natl. Acad. Sci. U.S.A. 107:19514-19519(2010).
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DR   EMBL; CP001840; ADP36807.1; -; Genomic_DNA.
DR   RefSeq; WP_013390360.1; NC_014638.1.
DR   RefSeq; YP_003971844.1; NC_014638.1.
DR   EnsemblBacteria; ADP36807; ADP36807; BBPR_1794.
DR   GeneID; 9889913; -.
DR   KEGG; bbp:BBPR_1794; -.
DR   PATRIC; fig|702459.3.peg.1853; -.
DR   KO; K01186; -.
DR   OMA; IMYTHIS; -.
DR   BioCyc; BBIF702459:G1GON-1764-MONOMER; -.
DR   Proteomes; UP000002312; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0052794; F:exo-alpha-(2->3)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052795; F:exo-alpha-(2->6)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0052796; F:exo-alpha-(2->8)-sialidase activity; IEA:UniProtKB-EC.
DR   GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR   InterPro; IPR018905; A-galactase_NEW3.
DR   InterPro; IPR011040; Sialidase.
DR   InterPro; IPR026856; Sialidase_fam.
DR   InterPro; IPR036278; Sialidase_sf.
DR   PANTHER; PTHR10628; PTHR10628; 1.
DR   Pfam; PF13088; BNR_2; 1.
DR   Pfam; PF10633; NPCBM_assoc; 1.
DR   SUPFAM; SSF50939; SSF50939; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002312};
KW   Glycosidase {ECO:0000313|EMBL:ADP36807.1};
KW   Hydrolase {ECO:0000313|EMBL:ADP36807.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     35       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        36    834       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5002608199.
FT   TRANSMEM    809    828       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      235    517       Sialidase. {ECO:0000259|Pfam:PF13088}.
FT   DOMAIN      573    635       NPCBM_assoc. {ECO:0000259|Pfam:PF10633}.
SQ   SEQUENCE   834 AA;  86833 MW;  B71938613C6AF157 CRC64;
     MVRSTKPSLL RRFGALVAAA AMLVVLPAGV STASAASDDA DMLTVTMTRT DALGDEVYVG
     DTLTYSFTNT NNTSSAFTAF PAESNLSGVL TTGTPNCRYE NLAGGASYPC STASHTITAD
     DLTAGSFTPR TVWKATSDRG GTQVLQDNIV STGDTVTVKE GKRPDPATIP TDRADGEAVR
     LATARQNLGT ECYRIPALAE APNGWILAAF DQRPNTAMAN GSGVKCWDAP QPNSIVQRIS
     KDGGKSWTPI QYVAQGKNAP ERYGYSDPSY VVDKETGEIF LFFVHSYNKG FADSQLGVDE
     SNRNVLHAVV VSSKDNGETW SKPRDITADI TKGYENEWKS RFATSGAGIQ LKYGKYKGRL
     IQQYAVGRTT GSNAAVSVYS DDHGKTWQAG NPVTGMLMDE NKVVELSDGR VMLNSRPGNG
     SGYRRVAISE DGGVNYGTVK NETQLPDPNN NAHITRAFPN APEGSAKAKV LLYSSPRANN
     EGRANGVVRI SLDDGTTWSS GKLYKEGSMA YSVITALSGA AGGGYGLLYE GAWVTGGGID
     SHDIMYTHIS MDWLGYLSAT ADDVTASVEE GASTVDVTVP VSNVGSVDYT GVTVTPADLP
     TGWSASPVNV GALASGASKD VTVTVNVPAT AKKDDVAKIV LRVTGTSAAN ANATTGFDGS
     ITVNVTEKSE PDPEPEPTIT GVSAVTSQAG VKVGDVFDAS KVSVTAAMSD GSSKALAAGE
     YSLSAVDADG KAVDLAEPFA AAGVVTVTVS VPVEGADPLT ASFTIDVAEK SADPEPKPEP
     KPEPEKPAGP KVDVPTEKPG LSKTGASTAG MSIVFVLLAL SGVAALSLRR RSVH
//
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