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Database: UniProt/TrEMBL
Entry: A0A168NSJ8_9CAUL
LinkDB: A0A168NSJ8_9CAUL
Original site: A0A168NSJ8_9CAUL 
ID   A0A168NSJ8_9CAUL        Unreviewed;       278 AA.
AC   A0A168NSJ8;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   25-APR-2018, entry version 12.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH] {ECO:0000256|PIRNR:PIRNR000094};
DE            EC=1.3.1.9 {ECO:0000256|PIRNR:PIRNR000094};
GN   ORFNames=A4249_14885 {ECO:0000313|EMBL:ANC54809.1};
OS   Brevundimonas sp. GW460-12-10-14-LB2.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Brevundimonas.
OX   NCBI_TaxID=1827469 {ECO:0000313|EMBL:ANC54809.1, ECO:0000313|Proteomes:UP000076746};
RN   [1] {ECO:0000313|EMBL:ANC54809.1, ECO:0000313|Proteomes:UP000076746}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GW460-12-10-14-LB2 {ECO:0000313|EMBL:ANC54809.1,
RC   ECO:0000313|Proteomes:UP000076746};
RA   Evans L.H., Alamgir A., Owens N., Weber N.D., Virtaneva K.,
RA   Barbian K., Babar A., Rosenke K.;
RL   Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a
CC       trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.
CC       {ECO:0000256|PIRNR:PIRNR000094}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily. {ECO:0000256|PIRNR:PIRNR000094}.
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DR   EMBL; CP015511; ANC54809.1; -; Genomic_DNA.
DR   RefSeq; WP_066554056.1; NZ_CP015511.1.
DR   EnsemblBacteria; ANC54809; ANC54809; A4249_14885.
DR   KEGG; brg:A4249_14885; -.
DR   KO; K00208; -.
DR   Proteomes; UP000076746; Chromosome.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43159:SF2; PTHR43159:SF2; 1.
DR   PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000076746};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   NAD {ECO:0000256|PIRNR:PIRNR000094, ECO:0000256|PIRSR:PIRSR000094-3};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000094}.
FT   NP_BIND      35     36       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   NP_BIND      80     81       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   ACT_SITE    162    162       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   ACT_SITE    172    172       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   BINDING      29     29       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING     108    108       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING     111    111       Substrate; via amide nitrogen and
FT                                carbonyl oxygen. {ECO:0000256|PIRSR:
FT                                PIRSR000094-2}.
FT   BINDING     179    179       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
SQ   SEQUENCE   278 AA;  29383 MW;  50D50EAE54DDDCE7 CRC64;
     MRRRTMATSE GWDMPTGDLM KGKKGLIMGV ANSSSIAWGI ASQLAAQGAE LAFTYLGESL
     ERRVRPLAES VGAKLLIPAD VTDDASMDAA FAELEKTFGT IDFVVHSVAF ANKDELKGSF
     VDNTTRDSFL LAMNISAFSF VDVSKRAAKL MPNGGSLITL TYLGSERVIP NYNTMGVAKA
     ALEAATRYIA RDLGPKNIRV NAISAGAMRT LSLAGISGGR GLHSKSAQFS LIKEETSMEG
     VAGAALWLCS DLGRSTTGEV VHVDAGFHAV GLPEDIEG
//
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