GenomeNet

Database: UniProt/TrEMBL
Entry: A8HZY9_AZOC5
LinkDB: A8HZY9_AZOC5
Original site: A8HZY9_AZOC5 
ID   A8HZY9_AZOC5            Unreviewed;       285 AA.
AC   A8HZY9;
DT   04-DEC-2007, integrated into UniProtKB/TrEMBL.
DT   04-DEC-2007, sequence version 1.
DT   25-APR-2018, entry version 74.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH] {ECO:0000256|PIRNR:PIRNR000094};
DE            EC=1.3.1.9 {ECO:0000256|PIRNR:PIRNR000094};
GN   OrderedLocusNames=AZC_4644 {ECO:0000313|EMBL:BAF90642.1};
OS   Azorhizobium caulinodans (strain ATCC 43989 / DSM 5975 / JCM 20966 /
OS   NBRC 14845 / NCIMB 13405 / ORS 571).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Xanthobacteraceae; Azorhizobium.
OX   NCBI_TaxID=438753 {ECO:0000313|EMBL:BAF90642.1, ECO:0000313|Proteomes:UP000000270};
RN   [1] {ECO:0000313|Proteomes:UP000000270}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 43989 / DSM 5975 / JCM 20966 / NBRC 14845 / NCIMB 13405 /
RC   ORS 571 {ECO:0000313|Proteomes:UP000000270};
RA   Lee K.B., Backer P.D., Aono T., Liu C.T., Suzuki S., Suzuki T.,
RA   Kaneko T., Yamada M., Tabata S., Kupfer D.M., Najar F.Z., Wiley G.B.,
RA   Roe B., Binnewies T., Ussery D., Vereecke D., Gevers D., Holsters M.,
RA   Oyaizu H.;
RT   "Complete genome sequence of the nitrogen-fixing bacterium
RT   Azorhizobium caulinodans ORS571.";
RL   Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a
CC       trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.
CC       {ECO:0000256|PIRNR:PIRNR000094}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily. {ECO:0000256|PIRNR:PIRNR000094}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AP009384; BAF90642.1; -; Genomic_DNA.
DR   RefSeq; WP_012173163.1; NC_009937.1.
DR   ProteinModelPortal; A8HZY9; -.
DR   STRING; 438753.AZC_4644; -.
DR   EnsemblBacteria; BAF90642; BAF90642; AZC_4644.
DR   KEGG; azc:AZC_4644; -.
DR   eggNOG; ENOG4105CSJ; Bacteria.
DR   eggNOG; COG0623; LUCA.
DR   KO; K00208; -.
DR   OMA; NHSIAWG; -.
DR   OrthoDB; POG091H06HU; -.
DR   BioCyc; ACAU438753:G1G2W-4816-MONOMER; -.
DR   Proteomes; UP000000270; Chromosome.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43159:SF2; PTHR43159:SF2; 1.
DR   PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000270};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   NAD {ECO:0000256|PIRNR:PIRNR000094, ECO:0000256|PIRSR:PIRSR000094-3};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000094};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000270}.
FT   NP_BIND      20     21       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   NP_BIND      65     66       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   NP_BIND     192    196       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   ACT_SITE    146    146       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   ACT_SITE    156    156       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   BINDING      14     14       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING      41     41       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING      93     93       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING     163    163       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
SQ   SEQUENCE   285 AA;  30483 MW;  036F18C8B724EB36 CRC64;
     MHDLMKGKRG LVMGVANDHS IAWGIAKSLA GQGAELAFTY QGEAMAKRVR PLAESLGAKV
     MMPCDVEDLA SVDALFDALR KEWGSLDFVV HAVAFSDKSE LKGRYADTTR DNFSRTMLIS
     CFSFTEIAKR AAELMTNGGS LITLTYGGAT RVMPNYNVMG VAKAALEASV RYLAADFGPQ
     GIRVNAISAG PVRTLAGAGI ADARLMFNYQ KRHAPLRRTV SLEEVGGSAL YLLSELSGGV
     TGEVHFVDSG YNIMSMPHPD VLKTQEDAEA KMAAETATVP PKAAE
//
DBGET integrated database retrieval system