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Database: UniProt/TrEMBL
Entry: B0CK17_BRUSI
LinkDB: B0CK17_BRUSI
Original site: B0CK17_BRUSI 
ID   B0CK17_BRUSI            Unreviewed;       272 AA.
AC   B0CK17;
DT   26-FEB-2008, integrated into UniProtKB/TrEMBL.
DT   26-FEB-2008, sequence version 1.
DT   18-JUL-2018, entry version 69.
DE   RecName: Full=Enoyl-[acyl-carrier-protein] reductase [NADH] {ECO:0000256|PIRNR:PIRNR000094};
DE            EC=1.3.1.9 {ECO:0000256|PIRNR:PIRNR000094};
GN   Name=fabI {ECO:0000313|EMBL:ABY39018.1};
GN   OrderedLocusNames=BSUIS_A2008 {ECO:0000313|EMBL:ABY39018.1};
OS   Brucella suis (strain ATCC 23445 / NCTC 10510).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Brucellaceae; Brucella.
OX   NCBI_TaxID=470137 {ECO:0000313|EMBL:ABY39018.1, ECO:0000313|Proteomes:UP000008545};
RN   [1] {ECO:0000313|EMBL:ABY39018.1, ECO:0000313|Proteomes:UP000008545}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23445 / NCTC 10510 {ECO:0000313|Proteomes:UP000008545};
RA   Setubal J.C., Bowns C., Boyle S., Crasta O.R., Czar M.J.,
RA   Dharmanolla C., Gillespie J.J., Kenyon R.W., Lu J., Mane S.,
RA   Mohapatra S., Nagrani S., Purkayastha A., Rajasimha H.K.,
RA   Shallom J.M., Shallom S., Shukla M., Snyder E.E., Sobral B.W.,
RA   Wattam A.R., Will R., Williams K., Yoo H., Bruce D., Detter C.,
RA   Munk C., Brettin T.S.;
RT   "Brucella suis ATCC 23445 whole genome shotgun sequencing project.";
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: An acyl-[acyl-carrier protein] + NAD(+) = a
CC       trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH.
CC       {ECO:0000256|PIRNR:PIRNR000094}.
CC   -!- SIMILARITY: Belongs to the short-chain dehydrogenases/reductases
CC       (SDR) family. FabI subfamily. {ECO:0000256|PIRNR:PIRNR000094}.
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DR   EMBL; CP000911; ABY39018.1; -; Genomic_DNA.
DR   RefSeq; WP_002965233.1; NC_010169.1.
DR   ProteinModelPortal; B0CK17; -.
DR   EnsemblBacteria; ABY39018; ABY39018; BSUIS_A2008.
DR   GeneID; 29594839; -.
DR   KEGG; bmt:BSUIS_A2008; -.
DR   PATRIC; fig|359391.4.peg.2261; -.
DR   KO; K00208; -.
DR   OMA; NHSIAWG; -.
DR   Proteomes; UP000008545; Chromosome I.
DR   GO; GO:0004318; F:enoyl-[acyl-carrier-protein] reductase (NADH) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   InterPro; IPR014358; Enoyl-ACP_Rdtase_NADH.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR002347; SDR_fam.
DR   PANTHER; PTHR43159:SF2; PTHR43159:SF2; 1.
DR   PIRSF; PIRSF000094; Enoyl-ACP_rdct; 1.
DR   PRINTS; PR00081; GDHRDH.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008545};
KW   Fatty acid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Fatty acid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid biosynthesis {ECO:0000256|PIRNR:PIRNR000094};
KW   Lipid metabolism {ECO:0000256|PIRNR:PIRNR000094};
KW   NAD {ECO:0000256|PIRNR:PIRNR000094, ECO:0000256|PIRSR:PIRSR000094-3};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR000094}.
FT   NP_BIND      65     66       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   NP_BIND     193    197       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   ACT_SITE    147    147       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   ACT_SITE    157    157       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR000094-1}.
FT   BINDING      14     14       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING      41     41       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING      93     93       NAD; via carbonyl oxygen.
FT                                {ECO:0000256|PIRSR:PIRSR000094-3}.
FT   BINDING     164    164       NAD. {ECO:0000256|PIRSR:PIRSR000094-3}.
SQ   SEQUENCE   272 AA;  29300 MW;  6DC206B38472DC31 CRC64;
     MEGLMQGKRG LIMGVANNHS LAWGIAKQLA AQGAELAFTY QGDALGKRVK PLAEQVGSDF
     VLPCDVEDIA TVDAVFEEIE KKWGGLDFLV HAIGFSDKTE LKGRYADVTT RENFSRTMVI
     SAYSFTEVAQ RAEKLMKDGG SILTLTYGGS TRTIPNYNVM GVAKAALEAM VRYLAADYGP
     QGIRVNAISA GPVRTLAGAG IGDARAIFSY QRRNSPLRRT VDIDDVGKSA VYLLSDLSSG
     VTGEIHFVDS GYNIVSMPTL EELKSSDSER GE
//
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