GenomeNet

Database: UniProt/TrEMBL
Entry: C8WJE1_EGGLE
LinkDB: C8WJE1_EGGLE
Original site: C8WJE1_EGGLE 
ID   C8WJE1_EGGLE            Unreviewed;       496 AA.
AC   C8WJE1;
DT   03-NOV-2009, integrated into UniProtKB/TrEMBL.
DT   03-NOV-2009, sequence version 1.
DT   25-APR-2018, entry version 57.
DE   RecName: Full=Glutamate decarboxylase {ECO:0000256|RuleBase:RU361171};
DE            EC=4.1.1.15 {ECO:0000256|RuleBase:RU361171};
GN   OrderedLocusNames=Elen_0149 {ECO:0000313|EMBL:ACV54143.1};
OS   Eggerthella lenta (strain ATCC 25559 / DSM 2243 / JCM 9979 /
OS   NCTC 11813 / VPI 0255) (Eubacterium lentum).
OC   Bacteria; Actinobacteria; Coriobacteriia; Eggerthellales;
OC   Eggerthellaceae; Eggerthella.
OX   NCBI_TaxID=479437 {ECO:0000313|EMBL:ACV54143.1, ECO:0000313|Proteomes:UP000001377};
RN   [1] {ECO:0000313|EMBL:ACV54143.1, ECO:0000313|Proteomes:UP000001377}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25559 / DSM 2243 / JCM 9979 / NCTC 11813 / VPI 0255
RC   {ECO:0000313|Proteomes:UP000001377};
RX   PubMed=21304654; DOI=10.4056/sigs.33592;
RA   Saunders E., Pukall R., Abt B., Lapidus A., Glavina Del Rio T.,
RA   Copeland A., Tice H., Cheng J.F., Lucas S., Chen F., Nolan M.,
RA   Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K.,
RA   Ovchinnikova G., Pati A., Chen A., Palaniappan K., Land M., Hauser L.,
RA   Chang Y.J., Jeffries C.D., Chain P., Meincke L., Sims D., Brettin T.,
RA   Detter J.C., Goker M., Bristow J., Eisen J.A., Markowitz V.,
RA   Hugenholtz P., Kyrpides N.C., Klenk H.P., Han C.;
RT   "Complete genome sequence of Eggerthella lenta type strain (IPP VPI
RT   0255).";
RL   Stand. Genomic Sci. 1:174-182(2009).
CC   -!- CATALYTIC ACTIVITY: L-glutamate = 4-aminobutanoate + CO(2).
CC       {ECO:0000256|RuleBase:RU361171}.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|PIRSR:PIRSR602129-50,
CC         ECO:0000256|RuleBase:RU000382};
CC   -!- SIMILARITY: Belongs to the group II decarboxylase family.
CC       {ECO:0000256|RuleBase:RU000382}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP001726; ACV54143.1; -; Genomic_DNA.
DR   RefSeq; WP_015759836.1; NC_013204.1.
DR   STRING; 479437.Elen_0149; -.
DR   EnsemblBacteria; ACV54143; ACV54143; Elen_0149.
DR   KEGG; ele:Elen_0149; -.
DR   eggNOG; ENOG4105CVK; Bacteria.
DR   eggNOG; COG0076; LUCA.
DR   HOGENOM; HOG000070228; -.
DR   KO; K01580; -.
DR   OMA; RPNLVMG; -.
DR   OrthoDB; POG091H06F5; -.
DR   BioCyc; ELEN479437:G1GFY-158-MONOMER; -.
DR   Proteomes; UP000001377; Chromosome.
DR   GO; GO:0004351; F:glutamate decarboxylase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0006536; P:glutamate metabolic process; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   InterPro; IPR010107; Glutamate_decarboxylase.
DR   InterPro; IPR002129; PyrdxlP-dep_de-COase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   PANTHER; PTHR43321; PTHR43321; 1.
DR   Pfam; PF00282; Pyridoxal_deC; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR01788; Glu-decarb-GAD; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001377};
KW   Decarboxylase {ECO:0000256|RuleBase:RU361171};
KW   Lyase {ECO:0000256|RuleBase:RU000382};
KW   Pyridoxal phosphate {ECO:0000256|PIRSR:PIRSR602129-50,
KW   ECO:0000256|RuleBase:RU000382};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001377}.
FT   COILED      438    458       {ECO:0000256|SAM:Coils}.
FT   MOD_RES     286    286       N6-(pyridoxal phosphate)lysine.
FT                                {ECO:0000256|PIRSR:PIRSR602129-50}.
SQ   SEQUENCE   496 AA;  55965 MW;  4615E18F418E7729 CRC64;
     MKEQTSTSKI LDSMDEGTKY STPIFGSEAS DVAMPRLKMN DKPVEPRITY EMIKEYLSIE
     GNATQNLTTF CQTYMEPMAT KIMAETMEKN AIDKDEYPMT ADLENRCVAM IGNLWHADPA
     EEPMGTSTVG SSEACMLGGL GMLFRWKKLA KDAGIDIYTA QRPNLVISAG YQVCWEKFCR
     YWDIEMRLVP LEKDHLSLNM DTVMDYVDDH TIGIAAILGI TYTGKFDDVQ KLDELVEAYN
     QQHPKLPIRI HVDGASGGMF APFVEPDLVW DFQLKNVWSI NCSGHKYGLV YPGIGWVVWR
     SKEALPEDLI FWVSYLGGEE ATMAINFSRS ASQIVGQYYV LMRNGFEGFK EIQERTLDVA
     RYLAAELKEM GVFEIYEDAS HIPIVCWGLK DDAGVEWSLY DLSDRLRMSG WLVPAYPMPA
     DMQDTTVQRV VARADFSMQL AIKLVEDMKK EMDTLNKAKF VTGNTQGVIR TGFNHGGRSA
     VDKGEKVQTK APTPQK
//
DBGET integrated database retrieval system