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Database: UniProt/TrEMBL
Entry: D8UD50_VOLCA
LinkDB: D8UD50_VOLCA
Original site: D8UD50_VOLCA 
ID   D8UD50_VOLCA            Unreviewed;       520 AA.
AC   D8UD50;
DT   05-OCT-2010, integrated into UniProtKB/TrEMBL.
DT   05-OCT-2010, sequence version 1.
DT   28-MAR-2018, entry version 32.
DE   RecName: Full=Phosphotransferase {ECO:0000256|RuleBase:RU362007};
DE            EC=2.7.1.- {ECO:0000256|RuleBase:RU362007};
GN   Name=hxk1 {ECO:0000313|EMBL:EFJ42371.1};
GN   ORFNames=VOLCADRAFT_67129 {ECO:0000313|EMBL:EFJ42371.1};
OS   Volvox carteri f. nagariensis.
OC   Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae;
OC   Chlamydomonadales; Volvocaceae; Volvox.
OX   NCBI_TaxID=3068 {ECO:0000313|Proteomes:UP000001058};
RN   [1] {ECO:0000313|EMBL:EFJ42371.1, ECO:0000313|Proteomes:UP000001058}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=f. Nagariensis / Eve {ECO:0000313|Proteomes:UP000001058};
RX   PubMed=20616280; DOI=10.1126/science.1188800;
RA   Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M.,
RA   Nishii I., Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K.,
RA   Hellsten U., Chapman J., Simakov O., Rensing S.A., Terry A.,
RA   Pangilinan J., Kapitonov V., Jurka J., Salamov A., Shapiro H.,
RA   Schmutz J., Grimwood J., Lindquist E., Lucas S., Grigoriev I.V.,
RA   Schmitt R., Kirk D., Rokhsar D.S.;
RT   "Genomic analysis of organismal complexity in the multicellular green
RT   alga Volvox carteri.";
RL   Science 329:223-226(2010).
CC   -!- SIMILARITY: Belongs to the hexokinase family.
CC       {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672880}.
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DR   EMBL; GL378383; EFJ42371.1; -; Genomic_DNA.
DR   RefSeq; XP_002956604.1; XM_002956558.1.
DR   GeneID; 9619936; -.
DR   KEGG; vcn:VOLCADRAFT_67129; -.
DR   InParanoid; D8UD50; -.
DR   KO; K00844; -.
DR   OMA; MIPTFVT; -.
DR   Proteomes; UP000001058; Unassembled WGS sequence.
DR   GO; GO:0005623; C:cell; IEA:GOC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0005536; F:glucose binding; IEA:InterPro.
DR   GO; GO:0004396; F:hexokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0001678; P:cellular glucose homeostasis; IEA:InterPro.
DR   GO; GO:0006096; P:glycolytic process; IEA:UniProtKB-KW.
DR   InterPro; IPR001312; Hexokinase.
DR   InterPro; IPR022673; Hexokinase_C.
DR   InterPro; IPR022672; Hexokinase_N.
DR   PANTHER; PTHR19443; PTHR19443; 1.
DR   Pfam; PF00349; Hexokinase_1; 1.
DR   Pfam; PF03727; Hexokinase_2; 1.
DR   PROSITE; PS51748; HEXOKINASE_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672869};
KW   Complete proteome {ECO:0000313|Proteomes:UP000001058};
KW   Glycolysis {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672870};
KW   Kinase {ECO:0000256|RuleBase:RU362007, ECO:0000256|SAAS:SAAS00672871,
KW   ECO:0000313|EMBL:EFJ42371.1};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672883};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001058};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transferase {ECO:0000256|RuleBase:RU362007,
KW   ECO:0000256|SAAS:SAAS00672884}.
FT   SIGNAL        1     20       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        21    520       Phosphotransferase. {ECO:0000256|SAM:
FT                                SignalP}.
FT                                /FTId=PRO_5003124383.
FT   DOMAIN       41    244       Hexokinase_1. {ECO:0000259|Pfam:PF00349}.
FT   DOMAIN      250    512       Hexokinase_2. {ECO:0000259|Pfam:PF03727}.
SQ   SEQUENCE   520 AA;  55114 MW;  E84AF198C88F40B6 CRC64;
     MRLAFALPVI GTSALAVALA LRKVELPLPT EDEEKVDLLL KRYREQLLAS PERLAEVEAE
     FLAQMRDGLS KRVVVDGKRM MMLPTFVTRL PDGTETGECY ALDLGGTNFR VMHVRLGPGK
     GEVAACNVEE VTLPKEIYTG AGDKLFDYLA TTLKSFIDRH SIPPSASQPQ PTLPVLGFCF
     SFAVEQDGLD SGRLLAWTKG FSCSGVVGND PVALLSAALE RVGRPCRVAA LLNDTVGVLA
     AQRYLDSDTE VGVIIGTGTN ACYVERLAAL TKWEPPPGAV AAAAAAAGGA GLDGRTAINM
     EWGAFFSPQL PRCMEDLQVD AASPHPGKYL FEKLLSGMFL GEAARRILFT IAKEASSGNV
     AVAAAAAMIP GPLATPGSLS SATLSAIVHD RSWGLRTTRR MLVSELGMHQ PSARAAEVVK
     EVCTLVARRS AQLTAMAVLA ILRHNGWAAA SPPRPVTVAI DGGVYERFTA YRTMLTEAVS
     EQLGKRSSEL FPLIKFVLSH DGSALGAAVL AAAAAVTATQ
//
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