GenomeNet

Database: UniProt/TrEMBL
Entry: E0J4G6_ECOLW
LinkDB: E0J4G6_ECOLW
Original site: E0J4G6_ECOLW 
ID   E0J4G6_ECOLW            Unreviewed;       346 AA.
AC   E0J4G6;
DT   02-NOV-2010, integrated into UniProtKB/TrEMBL.
DT   02-NOV-2010, sequence version 1.
DT   22-NOV-2017, entry version 50.
DE   RecName: Full=Aldose 1-epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE            EC=5.1.3.3 {ECO:0000256|PIRNR:PIRNR005096};
DE   AltName: Full=Galactose mutarotase {ECO:0000256|PIRNR:PIRNR005096};
GN   Name=galM {ECO:0000313|EMBL:ADT74319.1};
GN   OrderedLocusNames=ECW_m0811 {ECO:0000313|EMBL:ADT74319.1};
OS   Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666
OS   / NRRL B-766 / W).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=566546 {ECO:0000313|EMBL:ADT74319.1, ECO:0000313|Proteomes:UP000008525};
RN   [1] {ECO:0000313|EMBL:ADT74319.1, ECO:0000313|Proteomes:UP000008525}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W
RC   {ECO:0000313|Proteomes:UP000008525};
RX   PubMed=21208457; DOI=10.1186/1471-2164-12-9;
RA   Archer C.T., Kim J.F., Jeong H., Park J.H., Vickers C.E., Lee S.Y.,
RA   Nielsen L.K.;
RT   "The genome sequence of E. coli W (ATCC 9637): comparative genome
RT   analysis and an improved genome-scale reconstruction of E. coli.";
RL   BMC Genomics 12:9-9(2011).
CC   -!- FUNCTION: Converts alpha-aldose to the beta-anomer.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- CATALYTIC ACTIVITY: Alpha-D-glucose = beta-D-glucose.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002185; ADT74319.1; -; Genomic_DNA.
DR   RefSeq; WP_000931389.1; NZ_AEDF01000021.1.
DR   ProteinModelPortal; E0J4G6; -.
DR   SMR; E0J4G6; -.
DR   EnsemblBacteria; ADT74319; ADT74319; ECW_m0811.
DR   KEGG; ell:WFL_03930; -.
DR   KEGG; elw:ECW_m0811; -.
DR   PATRIC; fig|566546.30.peg.819; -.
DR   KO; K01785; -.
DR   OMA; ATWLSCK; -.
DR   UniPathway; UPA00242; -.
DR   Proteomes; UP000008525; Chromosome.
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR018052; Ald1_epimerase_CS.
DR   InterPro; IPR013458; Ald_epimerase_bac.
DR   InterPro; IPR015443; Aldose_1-epimerase.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   PIRSF; PIRSF005096; GALM; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
DR   TIGRFAMs; TIGR02636; galM_Leloir; 1.
DR   PROSITE; PS00545; ALDOSE_1_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008525};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR005096}.
FT   ACT_SITE    175    175       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   ACT_SITE    309    309       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   BINDING     245    245       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR005096-2}.
SQ   SEQUENCE   346 AA;  38190 MW;  4373732BAEA83E1D CRC64;
     MLNETPALAP DGQPYRLLTL RNNAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE
     CYQDQAAFLG ASIGRYANRI ANSRYTFDGE TVTLSPSQGV NQLHGGPEGF DKRRWQIVNQ
     NDRQVLFALS SDDGDQGFPG NLGATVQYRL TDDNRISITY RATVDKPCPV NMTNHVYFNL
     DGEQSDVRNH KLQILADEYL PVDEGGIPHD GLKSVAGTSF DFRSAKIIAS EFLADDDQRK
     VKGYDHAFLL QAKGDGKKVA AHVWSADEKL QLKVYTTAPA LQFYSGNFLG GTPSRGTEPY
     ADWQGLALES EFLPDSPNHP EWPQPDCFLR PGEEYSSLTE YQFIAE
//
DBGET integrated database retrieval system