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Database: UniProt/TrEMBL
Entry: F7I5R7_CALJA
LinkDB: F7I5R7_CALJA
Original site: F7I5R7_CALJA 
ID   F7I5R7_CALJA            Unreviewed;       611 AA.
AC   F7I5R7;
DT   27-JUL-2011, integrated into UniProtKB/TrEMBL.
DT   20-JUN-2018, sequence version 2.
DT   20-JUN-2018, entry version 53.
DE   SubName: Full=Proprotein convertase subtilisin/kexin type 2 {ECO:0000313|Ensembl:ENSCJAP00000008908};
GN   Name=PCSK2 {ECO:0000313|Ensembl:ENSCJAP00000008908};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|Ensembl:ENSCJAP00000008908, ECO:0000313|Proteomes:UP000008225};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000008908, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000008908}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUL-2011) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the peptidase S8 family.
CC       {ECO:0000256|RuleBase:RU003355}.
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DR   RefSeq; XP_002747512.1; XM_002747466.2.
DR   STRING; 9483.ENSCJAP00000008908; -.
DR   MEROPS; S08.073; -.
DR   Ensembl; ENSCJAT00000009413; ENSCJAP00000008908; ENSCJAG00000004853.
DR   GeneID; 100410189; -.
DR   KEGG; cjc:100410189; -.
DR   CTD; 5126; -.
DR   eggNOG; KOG3525; Eukaryota.
DR   eggNOG; KOG3526; Eukaryota.
DR   eggNOG; COG1404; LUCA.
DR   eggNOG; COG4935; LUCA.
DR   GeneTree; ENSGT00750000117358; -.
DR   KO; K01360; -.
DR   OMA; PQRGVLK; -.
DR   OrthoDB; EOG091G05HI; -.
DR   TreeFam; TF314277; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR   CDD; cd04059; Peptidases_S8_Protein_converta; 1.
DR   Gene3D; 2.60.120.260; -; 1.
DR   Gene3D; 3.30.70.850; -; 1.
DR   Gene3D; 3.40.50.200; -; 1.
DR   InterPro; IPR008979; Galactose-bd-like_sf.
DR   InterPro; IPR034182; Kexin/furin.
DR   InterPro; IPR002884; P_dom.
DR   InterPro; IPR000209; Peptidase_S8/S53_dom.
DR   InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR   InterPro; IPR023827; Peptidase_S8_Asp-AS.
DR   InterPro; IPR022398; Peptidase_S8_His-AS.
DR   InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR   InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR   InterPro; IPR032815; S8_pro-domain.
DR   InterPro; IPR038466; S8_pro-domain_sf.
DR   Pfam; PF01483; P_proprotein; 1.
DR   Pfam; PF00082; Peptidase_S8; 1.
DR   Pfam; PF16470; S8_pro-domain; 1.
DR   PRINTS; PR00723; SUBTILISIN.
DR   SUPFAM; SSF49785; SSF49785; 1.
DR   SUPFAM; SSF52743; SSF52743; 1.
DR   PROSITE; PS51829; P_HOMO_B; 1.
DR   PROSITE; PS00136; SUBTILASE_ASP; 1.
DR   PROSITE; PS00137; SUBTILASE_HIS; 1.
DR   PROSITE; PS00138; SUBTILASE_SER; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Hydrolase {ECO:0000256|RuleBase:RU003355};
KW   Protease {ECO:0000256|RuleBase:RU003355};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   Serine protease {ECO:0000256|RuleBase:RU003355}.
SQ   SEQUENCE   611 AA;  67404 MW;  96E1D425C545FC8B CRC64;
     MLSAQRQQRH PSISCPRFFS CLPGLCCGIC WLSRQAPLFV CLFLEKFSFL ADSQILYSSN
     MSPLSFQVKV ALQQEGFDRK KRGYRDLNAI DMNMNDPLFT KQWYLINTGQ ADGTPGLDLN
     VAEAWELGYT GKGVTIGIMD DGIDYLHPDL ASNYNAEASY DFSSNDPYPY PRYTDDWFNS
     HGTRCAGEVS AAANNNICGV GVAYNSKVAG IRMLDQPFMT DIIEASSISH MPQLIDIYSA
     SWGPTDNGKT VDGPRELTLQ AMADGVNKGR GGKGSIYVWA SGDGGSYDDC NCDGYASSMW
     TISINSAIND GRTALYDESC SSTLASTFSN GRKRNPEAGV ATTDLYGNCT LRHSGTSAAA
     PEAAGVFALA LEANLGLTWR DMQHLTVLTS KRNQLHDEVH QWRRNGVGLE FNHLFGYGVL
     DAGAMVKMAK DWKTVPERFH CVGGSAQDPE KIPSTGKLVL TLTTDACEGK ENFVRYLEHV
     QAVITVNATR RGDLNINMTS PMGTKSILLS RRPRDDDSKV GFDKWPFMTT HTWGEDARGT
     WTLELGFVGS TPQKGVLKEW TLMLHGTQSA PYIDQVVRDY QSKLAMSKKE ELEEELDEAV
     ERSLKSIFGK N
//
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