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Database: UniProt/TrEMBL
Entry: F8I5N2_SULAT
LinkDB: F8I5N2_SULAT
Original site: F8I5N2_SULAT 
ID   F8I5N2_SULAT            Unreviewed;       400 AA.
AC   F8I5N2;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   28-MAR-2018, entry version 42.
DE   RecName: Full=Elongation factor Tu {ECO:0000256|HAMAP-Rule:MF_00118, ECO:0000256|RuleBase:RU004061};
DE            Short=EF-Tu {ECO:0000256|HAMAP-Rule:MF_00118};
GN   Name=tufA {ECO:0000313|EMBL:AEJ38523.1};
GN   Synonyms=tuf {ECO:0000256|HAMAP-Rule:MF_00118};
GN   OrderedLocusNames=TPY_0321 {ECO:0000313|EMBL:AEJ38523.1};
OS   Sulfobacillus acidophilus (strain TPY).
OC   Bacteria; Firmicutes; Clostridia; Clostridiales;
OC   Clostridiales Family XVII. Incertae Sedis; Sulfobacillus.
OX   NCBI_TaxID=1051632 {ECO:0000313|EMBL:AEJ38523.1, ECO:0000313|Proteomes:UP000000291};
RN   [1] {ECO:0000313|EMBL:AEJ38523.1, ECO:0000313|Proteomes:UP000000291}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TPY {ECO:0000313|EMBL:AEJ38523.1,
RC   ECO:0000313|Proteomes:UP000000291};
RX   PubMed=21914875; DOI=10.1128/JB.05684-11;
RA   Li B., Chen Y., Liu Q., Hu S., Chen X.;
RT   "Complete genome analysis of Sulfobacillus acidophilus strain TPY,
RT   isolated from a hydrothermal vent in the Pacific ocean.";
RL   J. Bacteriol. 193:5555-5556(2011).
CC   -!- FUNCTION: This protein promotes the GTP-dependent binding of
CC       aminoacyl-tRNA to the A-site of ribosomes during protein
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBUNIT: Monomer. {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118}.
CC   -!- SIMILARITY: Belongs to the TRAFAC class translation factor GTPase
CC       superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A
CC       subfamily. {ECO:0000256|HAMAP-Rule:MF_00118}.
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DR   EMBL; CP002901; AEJ38523.1; -; Genomic_DNA.
DR   STRING; 1051632.TPY_0321; -.
DR   EnsemblBacteria; AEJ38523; AEJ38523; TPY_0321.
DR   KEGG; say:TPY_0321; -.
DR   PATRIC; fig|1051632.5.peg.294; -.
DR   eggNOG; ENOG4105CGV; Bacteria.
DR   eggNOG; COG0050; LUCA.
DR   KO; K02358; -.
DR   OMA; YGHIDCP; -.
DR   OrthoDB; POG091H00LA; -.
DR   Proteomes; UP000000291; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-UniRule.
DR   CDD; cd03697; EFTU_II; 1.
DR   HAMAP; MF_00118_B; EF_Tu_B; 1.
DR   InterPro; IPR004161; EFTu-like_2.
DR   InterPro; IPR033720; EFTU_2.
DR   InterPro; IPR031157; G_TR_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR000795; TF_GTP-bd_dom.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   InterPro; IPR009001; Transl_elong_EF1A/Init_IF2_C.
DR   InterPro; IPR004541; Transl_elong_EFTu/EF1A_bac/org.
DR   InterPro; IPR004160; Transl_elong_EFTu/EF1A_C.
DR   Pfam; PF00009; GTP_EFTU; 1.
DR   Pfam; PF03144; GTP_EFTU_D2; 1.
DR   Pfam; PF03143; GTP_EFTU_D3; 1.
DR   PRINTS; PR00315; ELONGATNFCT.
DR   SUPFAM; SSF50447; SSF50447; 1.
DR   SUPFAM; SSF50465; SSF50465; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00485; EF-Tu; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS00301; G_TR_1; 1.
DR   PROSITE; PS51722; G_TR_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000000291};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Elongation factor {ECO:0000256|HAMAP-Rule:MF_00118,
KW   ECO:0000313|EMBL:AEJ38523.1};
KW   GTP-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Protein biosynthesis {ECO:0000256|HAMAP-Rule:MF_00118};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000291}.
FT   DOMAIN       10    209       Tr-type G. {ECO:0000259|PROSITE:PS51722}.
FT   NP_BIND      19     26       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND      81     85       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
FT   NP_BIND     136    139       GTP. {ECO:0000256|HAMAP-Rule:MF_00118}.
SQ   SEQUENCE   400 AA;  43906 MW;  7DDAF9CBDC6EA25C CRC64;
     MAKKKYERTK PHVNVGTIGH VDHGKTTLTA AITRVLSTQG KAEFTAYDQI DKAPEERERG
     ITIATAHVEY ETDKRHYAHV DCPGHADYVK NMITGAAQMD GAILVVSAAD GPMPQTREHI
     LLARQVGVPN IVVFLNKADM VDDPELMELV EIEVRDLLSS YEFPGDEIPV VAGSALKALE
     CGCGRRDCEW CGKIWQLMDA VDDYIPTPTR DTDKPFLMPV EDTHSITGRG TVVTGRVERG
     QIKVGEEVEI VGLTDTAKKT VVTGVEMFRK TLDVAVAGDN IGCLLRGVDK EEVERGQVLA
     KPGSIKPHTK YSAEVYVLTK EEGGRHTPFF NGYRPQFYFR TTDVTGVVQL PEGVEMVMPG
     DNIRMDVELI APIAMEEGLR FAIREGGRTV GAGVVTAIKE
//
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