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Database: UniProt/TrEMBL
Entry: F8MG70_NEUT8
LinkDB: F8MG70_NEUT8
Original site: F8MG70_NEUT8 
ID   F8MG70_NEUT8            Unreviewed;       779 AA.
AC   F8MG70;
DT   21-SEP-2011, integrated into UniProtKB/TrEMBL.
DT   21-SEP-2011, sequence version 1.
DT   12-SEP-2018, entry version 46.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGO59396.1};
GN   ORFNames=NEUTE1DRAFT_121214 {ECO:0000313|EMBL:EGO59396.1};
OS   Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae;
OC   Neurospora.
OX   NCBI_TaxID=510951 {ECO:0000313|EMBL:EGO59396.1, ECO:0000313|Proteomes:UP000008065};
RN   [1] {ECO:0000313|Proteomes:UP000008065}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FGSC 2508 / P0657 {ECO:0000313|Proteomes:UP000008065};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V.,
RA   Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to
RT   self-fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|SAAS:SAAS00591578}.
CC   -!- SUBCELLULAR LOCATION: Chromosome {ECO:0000256|SAAS:SAAS00563877}.
CC       Nucleus {ECO:0000256|SAAS:SAAS00574581}.
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DR   EMBL; GL891303; EGO59396.1; -; Genomic_DNA.
DR   RefSeq; XP_009849632.1; XM_009851330.1.
DR   ProteinModelPortal; F8MG70; -.
DR   EnsemblFungi; EGO59396; EGO59396; NEUTE1DRAFT_121214.
DR   GeneID; 20824083; -.
DR   KEGG; nte:NEUTE1DRAFT121214; -.
DR   EuPathDB; FungiDB:NEUTE1DRAFT_121214; -.
DR   KO; K11419; -.
DR   OrthoDB; EOG092C1QPC; -.
DR   Proteomes; UP000008065; Unassembled WGS sequence.
DR   GO; GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 1.10.1040.10; -; 2.
DR   InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR029154; NADP-bd.
DR   InterPro; IPR003616; Post-SET_dom.
DR   InterPro; IPR007728; Pre-SET_dom.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF14833; NAD_binding_11; 2.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF05033; Pre-SET; 1.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00468; PreSET; 1.
DR   SMART; SM00317; SET; 1.
DR   SUPFAM; SSF48179; SSF48179; 2.
DR   SUPFAM; SSF51735; SSF51735; 1.
DR   PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
DR   PROSITE; PS50868; POST_SET; 1.
DR   PROSITE; PS50867; PRE_SET; 1.
DR   PROSITE; PS50280; SET; 1.
PE   4: Predicted;
KW   Chromosome {ECO:0000256|SAAS:SAAS00508265};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008065};
KW   Methyltransferase {ECO:0000256|SAAS:SAAS00590675};
KW   Nucleus {ECO:0000256|SAAS:SAAS00574642};
KW   S-adenosyl-L-methionine {ECO:0000256|SAAS:SAAS00591079};
KW   Transferase {ECO:0000256|SAAS:SAAS00591533}.
FT   DOMAIN      525    607       Pre-SET. {ECO:0000259|PROSITE:PS50867}.
FT   DOMAIN      610    745       SET. {ECO:0000259|PROSITE:PS50280}.
FT   DOMAIN      763    779       Post-SET. {ECO:0000259|PROSITE:PS50868}.
SQ   SEQUENCE   779 AA;  83818 MW;  3F13C1A4A8F1D54F CRC64;
     MSDTKQPVAF IGLGAMGFGM ATHLIKQGYP VTGFDVWPPT LEKFTSAGGL TASTPASAVA
     DKPLCVCMVA TAQQAQSVLI DGPDAAAPAL PQGAVLLLCS TVPCDYVQSL AKQLSAIGRP
     DIHLIDCPVS GGAARAADGT LSIMAGVPSE KALGKSKPLL EELADPAKLY IVQGGIGAGS
     NMKMVHQVLA AVQILAASEA MGLATHLGLD LARTNEAVLK SDAWNWMFEH RTPRMLTGYQ
     PIASATVIIV KDTSIITAEA RRSGFPTLMT SVAEQVYFSA VGRGYGADDD SGLVRLYAEG
     KGKVGPVQGT AASGEEKLAL VIGLLKGILL CSAAEALAFA DRVGLDLDQV FDLCINAAGG
     SQMLKKYGPS IIKAFREGTA RQGWAAAESE TSLKEIADGL SAAVEEAQRL KAPVFLGSQA
     LNVVRVALQS SPDGVAAGAV VKVWNSTSME KAFRPHFFNH GKPDANPKEK KNCHWCQIRS
     FATHAQLPIS IVNREDDAFL NPNFRFIDHS IIGKNVPVAD QSFRVGCSCA SDEECMYSTC
     QCLDEMAPDS DEEADPYTRK KRFAYYSQGA KKGLLRDRVL QSQEPIYECH QGCACSKDCP
     NRVVERGRTV PLQIFRTKDR GWGVKCPVNI KRGQFVDRYL GEIITSEEAD RRRAESTIAR
     RKDVYLFALD KFSDPDSLDP LLAGQPLEVD GEYMSGPTRF INHSCDPNMA IFARVGDHAD
     KHIHDLALFA IKDIPKGTEL TFDYVNGLTG LESDAHDPSK ISEMTKCLCG TAKCRGYLW
//
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