GenomeNet

Database: UniProt/TrEMBL
Entry: J3JYL1_DENPD
LinkDB: J3JYL1_DENPD
Original site: J3JYL1_DENPD 
ID   J3JYL1_DENPD            Unreviewed;       153 AA.
AC   J3JYL1;
DT   03-OCT-2012, integrated into UniProtKB/TrEMBL.
DT   03-OCT-2012, sequence version 1.
DT   25-OCT-2017, entry version 38.
DE   RecName: Full=Superoxide dismutase [Cu-Zn] {ECO:0000256|RuleBase:RU000393};
DE            EC=1.15.1.1 {ECO:0000256|RuleBase:RU000393};
GN   Name=109538429 {ECO:0000313|EnsemblMetazoa:ENN76399};
GN   ORFNames=D910_11395 {ECO:0000313|EMBL:ERL94113.1}, YQE_07060
GN   {ECO:0000313|EMBL:ENN76399.1};
OS   Dendroctonus ponderosae (Mountain pine beetle).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta;
OC   Pterygota; Neoptera; Holometabola; Coleoptera; Polyphaga;
OC   Cucujiformia; Curculionidae; Scolytinae; Dendroctonus.
OX   NCBI_TaxID=77166 {ECO:0000313|EMBL:AEE63298.1};
RN   [1] {ECO:0000313|EMBL:AEE63298.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Midgut and adhering fatbody of emerged adults of both sexes
RC   after feeding on lodgepole pine for up to 64 h
RC   {ECO:0000313|EMBL:AEE63298.1};
RX   PubMed=22516182; DOI=10.1016/j.ibmb.2012.03.010;
RA   Keeling C.I., Henderson H., Li M., Yuen M., Clark E.L., Fraser J.D.,
RA   Huber D.P., Liao N.Y., Roderick Docking T., Birol I., Chan S.K.,
RA   Taylor G.A., Palmquist D., Jones S.J., Bohlmann J.;
RT   "Transcriptome and full-length cDNA resources for the mountain pine
RT   beetle, Dendroctonus ponderosae Hopkins, a major insect pest of pine
RT   forests.";
RL   Insect Biochem. Mol. Biol. 42:525-536(2012).
RN   [2] {ECO:0000313|EMBL:ENN76399.1, ECO:0000313|Proteomes:UP000019118, ECO:0000313|Proteomes:UP000030742}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=23537049; DOI=10.1186/gb-2013-14-3-r27;
RA   Keeling C.I., Yuen M.M., Liao N.Y., Roderick Docking T., Chan S.K.,
RA   Taylor G.A., Palmquist D.L., Jackman S.D., Nguyen A., Li M.,
RA   Henderson H., Janes J.K., Zhao Y., Pandoh P., Moore R., Sperling F.A.,
RA   W Huber D.P., Birol I., Jones S.J., Bohlmann J.;
RT   "Draft genome of the mountain pine beetle, Dendroctonus ponderosae
RT   Hopkins, a major forest pest.";
RL   Genome Biol. 14:R27-R27(2013).
RN   [3] {ECO:0000313|EnsemblMetazoa:ENN76399}
RP   IDENTIFICATION.
RG   EnsemblMetazoa;
RL   Submitted (JAN-2017) to UniProtKB.
CC   -!- FUNCTION: Destroys radicals which are normally produced within the
CC       cells and which are toxic to biological systems.
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- CATALYTIC ACTIVITY: 2 superoxide + 2 H(+) = O(2) + H(2)O(2).
CC       {ECO:0000256|RuleBase:RU000393}.
CC   -!- COFACTOR:
CC       Name=Cu cation; Xref=ChEBI:CHEBI:23378;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 copper ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|RuleBase:RU000393};
CC       Note=Binds 1 zinc ion per subunit.
CC       {ECO:0000256|RuleBase:RU000393};
CC   -!- SIMILARITY: Belongs to the Cu-Zn superoxide dismutase family.
CC       {ECO:0000256|RuleBase:RU000393}.
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DR   EMBL; APGK01040371; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; BT128340; AEE63298.1; -; mRNA.
DR   EMBL; KB740979; ENN76399.1; -; Genomic_DNA.
DR   EMBL; KB632379; ERL94113.1; -; Genomic_DNA.
DR   RefSeq; XP_019761213.1; XM_019905654.1.
DR   EnsemblMetazoa; ENN76399; ENN76399; YQE_07060.
DR   GeneID; 109538429; -.
DR   KEGG; dpa:109538429; -.
DR   KO; K04565; -.
DR   OMA; IHTFGDN; -.
DR   Proteomes; UP000019118; Unassembled WGS sequence.
DR   Proteomes; UP000030742; Unassembled WGS sequence.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004784; F:superoxide dismutase activity; IEA:UniProtKB-EC.
DR   CDD; cd00305; Cu-Zn_Superoxide_Dismutase; 1.
DR   Gene3D; 2.60.40.200; -; 1.
DR   InterPro; IPR036423; SOD-like_Cu/Zn_dom_sf.
DR   InterPro; IPR024134; SOD_Cu/Zn_/chaperone.
DR   InterPro; IPR018152; SOD_Cu/Zn_BS.
DR   InterPro; IPR001424; SOD_Cu_Zn_dom.
DR   PANTHER; PTHR10003; PTHR10003; 1.
DR   Pfam; PF00080; Sod_Cu; 1.
DR   PRINTS; PR00068; CUZNDISMTASE.
DR   SUPFAM; SSF49329; SSF49329; 1.
DR   PROSITE; PS00087; SOD_CU_ZN_1; 1.
DR   PROSITE; PS00332; SOD_CU_ZN_2; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000019118,
KW   ECO:0000313|Proteomes:UP000030742};
KW   Copper {ECO:0000256|RuleBase:RU000393};
KW   Metal-binding {ECO:0000256|RuleBase:RU000393};
KW   Oxidoreductase {ECO:0000256|RuleBase:RU000393};
KW   Reference proteome {ECO:0000313|Proteomes:UP000030742};
KW   Zinc {ECO:0000256|RuleBase:RU000393}.
FT   DOMAIN       11    147       Sod_Cu. {ECO:0000259|Pfam:PF00080}.
FT   NON_TER       1      1       {ECO:0000313|EMBL:ENN76399.1}.
SQ   SEQUENCE   153 AA;  15681 MW;  EE947131E0726370 CRC64;
     MVKAVAVLKS EVVNGTVFFS QEGNNPVQVN GSLSGLKEGL HGFHIHEFGD NTNGCISAGP
     HFNPNDKEHG GPTDADRHAG DLGNIEANAE GVAKINITDK QISLSGANSI IGRTVVVHAD
     PDDLGKGGHE LSKTTGNAGG RLACAVIGLA QPN
//
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