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Database: UniProt/TrEMBL
Entry: L5KXH5_PTEAL
LinkDB: L5KXH5_PTEAL
Original site: L5KXH5_PTEAL 
ID   L5KXH5_PTEAL            Unreviewed;       604 AA.
AC   L5KXH5;
DT   06-MAR-2013, integrated into UniProtKB/TrEMBL.
DT   06-MAR-2013, sequence version 1.
DT   22-NOV-2017, entry version 21.
DE   SubName: Full=Prostaglandin G/H synthase 2 {ECO:0000313|EMBL:ELK16169.1};
GN   ORFNames=PAL_GLEAN10017647 {ECO:0000313|EMBL:ELK16169.1};
OS   Pteropus alecto (Black flying fox).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Laurasiatheria; Chiroptera; Megachiroptera;
OC   Pteropodidae; Pteropodinae; Pteropus.
OX   NCBI_TaxID=9402 {ECO:0000313|EMBL:ELK16169.1, ECO:0000313|Proteomes:UP000010552};
RN   [1] {ECO:0000313|Proteomes:UP000010552}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=23258410; DOI=10.1126/science.1230835;
RA   Zhang G., Cowled C., Shi Z., Huang Z., Bishop-Lilly K.A., Fang X.,
RA   Wynne J.W., Xiong Z., Baker M.L., Zhao W., Tachedjian M., Zhu Y.,
RA   Zhou P., Jiang X., Ng J., Yang L., Wu L., Xiao J., Feng Y., Chen Y.,
RA   Sun X., Zhang Y., Marsh G.A., Crameri G., Broder C.C., Frey K.G.,
RA   Wang L.F., Wang J.;
RT   "Comparative analysis of bat genomes provides insight into the
RT   evolution of flight and immunity.";
RL   Science 339:456-460(2013).
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation
CC       of feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR   EMBL; KB030474; ELK16169.1; -; Genomic_DNA.
DR   RefSeq; XP_006907791.1; XM_006907729.2.
DR   GeneID; 102886561; -.
DR   KEGG; pale:102886561; -.
DR   CTD; 5743; -.
DR   InParanoid; L5KXH5; -.
DR   KO; K11987; -.
DR   Proteomes; UP000010552; Unassembled WGS sequence.
DR   GO; GO:0020037; F:heme binding; IEA:InterPro.
DR   GO; GO:0004601; F:peroxidase activity; IEA:InterPro.
DR   GO; GO:0004666; F:prostaglandin-endoperoxide synthase activity; IEA:InterPro.
DR   GO; GO:0019371; P:cyclooxygenase pathway; IEA:InterPro.
DR   GO; GO:0006954; P:inflammatory response; IEA:InterPro.
DR   GO; GO:0008217; P:regulation of blood pressure; IEA:InterPro.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   Gene3D; 1.10.640.10; -; 1.
DR   InterPro; IPR029576; COX-2.
DR   InterPro; IPR000742; EGF-like_dom.
DR   InterPro; IPR010255; Haem_peroxidase.
DR   InterPro; IPR019791; Haem_peroxidase_animal.
DR   InterPro; IPR037120; Haem_peroxidase_sf.
DR   PANTHER; PTHR11903:SF8; PTHR11903:SF8; 1.
DR   Pfam; PF03098; An_peroxidase; 1.
DR   PRINTS; PR00457; ANPEROXIDASE.
DR   SUPFAM; SSF48113; SSF48113; 1.
DR   PROSITE; PS50026; EGF_3; 1.
DR   PROSITE; PS50292; PEROXIDASE_3; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000010552};
KW   EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW   Reference proteome {ECO:0000313|Proteomes:UP000010552};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     17       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        18    604       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5003969604.
FT   DOMAIN       17     55       EGF-like. {ECO:0000259|PROSITE:PS50026}.
SQ   SEQUENCE   604 AA;  68919 MW;  1A66FF52E43E44FD CRC64;
     MLARALVLCA ALALSGAANP CCSNPCQNKG VCMSVGFDQY KCDCTRTGFY GENCSTPEFL
     TRIKLYLKPT PNTVHYILTH FKGVWNIVNN IPFLRNAIMK YVLTSRSHLV DSPPTYNAHY
     GYKSWEAFSN LSYYTRVLPP VAHDCPTPMG VKGKKELPAS EVIVEKFLLR RKFVPDPQGT
     NLMFAFFAQH FTHQFFKTDH KRGPAFTKGL GHGVDLNHIY GETLDRQHKL RLFKDGKLKY
     QIIDGEMYPP TVKDTQVEMI YPPHVPEHLR FAVGQEVFGL VPGLMMYATI WLREHNRVCD
     VLKQEHPEWD DERLFQTSRL ILIGETIKIV IEDYVQHLSG YHFKLRFDPE LLFNQQFQYQ
     NRIAAEFNTL YHWHPLLPDT FQIEDQEYDY RQFIYNNSIL LEHGLTQFVE SFSRQIAGRV
     AGGRNFPAAI QYVAKASIDQ SRQMKYQALN EYRKRFLMKP YESFEELTGE KEMAAELEAL
     YGDIDAMELY PALLVEKPRP DAIFGETMVE LGAPFSLKGL MGNAICSPHY WKPSTFGGEV
     GFKIINTASI QSLICNNVKG CPSTSFSVQD PPPTKAVTIR ASPSHSGLDD INPTVLLKGR
     STEL
//
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