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Database: UniProt/TrEMBL
Entry: M2Z8X8_PSEFD
LinkDB: M2Z8X8_PSEFD
Original site: M2Z8X8_PSEFD 
ID   M2Z8X8_PSEFD            Unreviewed;       967 AA.
AC   M2Z8X8;
DT   01-MAY-2013, integrated into UniProtKB/TrEMBL.
DT   01-MAY-2013, sequence version 1.
DT   23-MAY-2018, entry version 25.
DE   RecName: Full=DNA ligase {ECO:0000256|RuleBase:RU000617};
DE            EC=6.5.1.1 {ECO:0000256|RuleBase:RU000617};
GN   ORFNames=MYCFIDRAFT_132548 {ECO:0000313|EMBL:EME86230.1};
OS   Pseudocercospora fijiensis (strain CIRAD86) (Black leaf streak disease
OS   fungus) (Mycosphaerella fijiensis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Dothideomycetes; Dothideomycetidae; Capnodiales; Mycosphaerellaceae;
OC   Pseudocercospora.
OX   NCBI_TaxID=383855 {ECO:0000313|EMBL:EME86230.1, ECO:0000313|Proteomes:UP000016932};
RN   [1] {ECO:0000313|EMBL:EME86230.1, ECO:0000313|Proteomes:UP000016932}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIRAD86 {ECO:0000313|EMBL:EME86230.1,
RC   ECO:0000313|Proteomes:UP000016932};
RX   PubMed=23236275; DOI=10.1371/journal.ppat.1003037;
RA   Ohm R.A., Feau N., Henrissat B., Schoch C.L., Horwitz B.A.,
RA   Barry K.W., Condon B.J., Copeland A.C., Dhillon B., Glaser F.,
RA   Hesse C.N., Kosti I., LaButti K., Lindquist E.A., Lucas S.,
RA   Salamov A.A., Bradshaw R.E., Ciuffetti L., Hamelin R.C., Kema G.H.J.,
RA   Lawrence C., Scott J.A., Spatafora J.W., Turgeon B.G.,
RA   de Wit P.J.G.M., Zhong S., Goodwin S.B., Grigoriev I.V.;
RT   "Diverse lifestyles and strategies of plant pathogenesis encoded in
RT   the genomes of eighteen Dothideomycetes fungi.";
RL   PLoS Pathog. 8:E1003037-E1003037(2012).
CC   -!- CATALYTIC ACTIVITY: ATP + (deoxyribonucleotide)(n)-3'-hydroxyl +
CC       5'-phospho-(deoxyribonucleotide)(m) = (deoxyribonucleotide)(n+m) +
CC       AMP + diphosphate. {ECO:0000256|RuleBase:RU000617}.
CC   -!- SIMILARITY: Belongs to the ATP-dependent DNA ligase family.
CC       {ECO:0000256|RuleBase:RU004196}.
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DR   EMBL; KB446556; EME86230.1; -; Genomic_DNA.
DR   RefSeq; XP_007923579.1; XM_007925388.1.
DR   EnsemblFungi; EME86230; EME86230; MYCFIDRAFT_132548.
DR   GeneID; 19330817; -.
DR   KEGG; pfj:MYCFIDRAFT_132548; -.
DR   KO; K10777; -.
DR   OrthoDB; EOG092C18KW; -.
DR   Proteomes; UP000016932; Unassembled WGS sequence.
DR   GO; GO:0032807; C:DNA ligase IV complex; IEA:EnsemblFungi.
DR   GO; GO:0000790; C:nuclear chromatin; IEA:EnsemblFungi.
DR   GO; GO:0005730; C:nucleolus; IEA:EnsemblFungi.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0003910; F:DNA ligase (ATP) activity; IEA:UniProtKB-EC.
DR   GO; GO:0071897; P:DNA biosynthetic process; IEA:InterPro.
DR   GO; GO:0051103; P:DNA ligation involved in DNA repair; IEA:InterPro.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR   CDD; cd00027; BRCT; 1.
DR   Gene3D; 1.10.3260.10; -; 1.
DR   Gene3D; 3.40.50.10190; -; 2.
DR   InterPro; IPR001357; BRCT_dom.
DR   InterPro; IPR036420; BRCT_dom_sf.
DR   InterPro; IPR000977; DNA_ligase_ATP-dep.
DR   InterPro; IPR012309; DNA_ligase_ATP-dep_C.
DR   InterPro; IPR012310; DNA_ligase_ATP-dep_cent.
DR   InterPro; IPR016059; DNA_ligase_ATP-dep_CS.
DR   InterPro; IPR012308; DNA_ligase_ATP-dep_N.
DR   InterPro; IPR036599; DNA_ligase_N_sf.
DR   InterPro; IPR029710; LIG4.
DR   InterPro; IPR012340; NA-bd_OB-fold.
DR   PANTHER; PTHR10459:SF7; PTHR10459:SF7; 1.
DR   Pfam; PF16589; BRCT_2; 1.
DR   Pfam; PF04679; DNA_ligase_A_C; 1.
DR   Pfam; PF01068; DNA_ligase_A_M; 1.
DR   Pfam; PF04675; DNA_ligase_A_N; 1.
DR   SMART; SM00292; BRCT; 2.
DR   SUPFAM; SSF117018; SSF117018; 1.
DR   SUPFAM; SSF50249; SSF50249; 1.
DR   SUPFAM; SSF52113; SSF52113; 2.
DR   TIGRFAMs; TIGR00574; dnl1; 1.
DR   PROSITE; PS50172; BRCT; 2.
DR   PROSITE; PS00697; DNA_LIGASE_A1; 1.
DR   PROSITE; PS50160; DNA_LIGASE_A3; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|RuleBase:RU000617};
KW   Complete proteome {ECO:0000313|Proteomes:UP000016932};
KW   DNA damage {ECO:0000256|RuleBase:RU000617};
KW   DNA recombination {ECO:0000256|RuleBase:RU000617};
KW   DNA repair {ECO:0000256|RuleBase:RU000617};
KW   DNA replication {ECO:0000256|RuleBase:RU000617};
KW   Ligase {ECO:0000256|RuleBase:RU000617};
KW   Nucleotide-binding {ECO:0000256|RuleBase:RU000617};
KW   Reference proteome {ECO:0000313|Proteomes:UP000016932}.
FT   DOMAIN      414    537       DNA_LIGASE_A3. {ECO:0000259|PROSITE:
FT                                PS50160}.
FT   DOMAIN      710    802       BRCT. {ECO:0000259|PROSITE:PS50172}.
FT   DOMAIN      875    966       BRCT. {ECO:0000259|PROSITE:PS50172}.
SQ   SEQUENCE   967 AA;  110840 MW;  97A2ED11E153AB37 CRC64;
     MYGRGTMTEQ ELDEKYPNRP HNHSRTLPFR DLFFTLFNPL NDNRKKPSGP AIARKKLGSY
     GGPSQAPNEV RRQIIDRFIS RWRKEVGDDI YPAMRLIVPE KDRDRGMYGL KEMTIAKLLV
     KILKIDKNSD DGRNLTHWKQ PGLNSTSAMA GDFAGRCFEV ISKRPMRTTP GDMTIAEVNE
     RLDRLAVAQK EENQLPILEQ FYSRMNAEEM MWLVRMILRQ MKVGATEKTF FEIWHPDAET
     LFNISSSLRR VCWELYDPAV RLEGESRGIC LMQCFQPQLA AFQMRSTEHM VAKMGTTDED
     PVFWIEEKLD GERMQMHVME DDDHPGGVRF GFWSRKAKDY TYLYGSGFED DHSALTRHIK
     DAFASGVRNI ILDGEMITWD IQLDAIVTFG TLKTAAIEQQ QNPFADGNRP LYRVFDCLYL
     NDKDLTRYTL RDRRNALQCS IKNVRRRIEI HEYQEEKTAS KVDETLRRVV AEASEGLVLK
     NPRSLYHLNA RNDDWIKVKP EYMTEFGESL DCIVVGGYYG SGKRGGGLSS FLCGLYVPSQ
     KKEIQPDINP QKTLSFFKVG GGFSASDYAQ IKHMTEGKWN DWDRKKPPFD WVELGGGMVK
     QYERPDVWIK PEDSFVVSVK AASVGASDQF ACGFTLRFPR FKKLRTDKSW QQALSHDDFI
     ELKTKAQNEK EEKKMKMDES RRGRKTKKRK KEIVIQGQEE GDLKTPYAGP VTKVFEGLSF
     FIMTEAPKPI KKSKAELEQL VKANGGQIVA SHKDPKTILV ADRNVVKVAS VKKSDNRNIV
     KPSWLLDCIK QSELDVGRPT LLLPLEPHHL EYTQSADQGK FDDNVDEYGD SYARDVTPSS
     LLALCNKMPA KVEDGYEPLE ILEQLNEQNN ELDALAGFMF RGTKAYIEPS IPRESIRLYE
     FAGGDLAKTL KDEDITQVVV QQGSQSLADI RKAVSSRSKL PRIVTEDWVK ESWIEETRLD
     EERFAPV
//
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