GenomeNet

Database: UniProt/TrEMBL
Entry: Q08TQ6_STIAD
LinkDB: Q08TQ6_STIAD
Original site: Q08TQ6_STIAD 
ID   Q08TQ6_STIAD            Unreviewed;       691 AA.
AC   Q08TQ6;
DT   31-OCT-2006, integrated into UniProtKB/TrEMBL.
DT   31-OCT-2006, sequence version 1.
DT   20-JUN-2018, entry version 86.
DE   RecName: Full=Catalase {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498};
DE            EC=1.11.1.6 {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498};
GN   Name=katE {ECO:0000313|EMBL:ADO71963.1};
GN   OrderedLocusNames=STAUR_4181 {ECO:0000313|EMBL:ADO71963.1};
GN   ORFNames=STIAU_6374 {ECO:0000313|EMBL:EAU63865.1};
OS   Stigmatella aurantiaca (strain DW4/3-1).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Archangiaceae; Stigmatella.
OX   NCBI_TaxID=378806 {ECO:0000313|EMBL:EAU63865.1, ECO:0000313|Proteomes:UP000032702};
RN   [1] {ECO:0000313|EMBL:EAU63865.1, ECO:0000313|Proteomes:UP000032702}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DW4/3-1 {ECO:0000313|EMBL:EAU63865.1,
RC   ECO:0000313|Proteomes:UP000032702};
RA   Nierman W.C.;
RL   Submitted (APR-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:ADO71963.1, ECO:0000313|Proteomes:UP000001351}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DW4/3-1 {ECO:0000313|EMBL:ADO71963.1,
RC   ECO:0000313|Proteomes:UP000001351};
RX   PubMed=21037205; DOI=10.1093/molbev/msq292;
RA   Huntley S., Hamann N., Wegener-Feldbrugge S., Treuner-Lange A.,
RA   Kube M., Reinhardt R., Klages S., Muller R., Ronning C.M.,
RA   Nierman W.C., Sogaard-Andersen L.;
RT   "Comparative genomic analysis of fruiting body formation in
RT   Myxococcales.";
RL   Mol. Biol. Evol. 28:1083-1097(2011).
CC   -!- FUNCTION: Serves to protect cells from the toxic effects of
CC       hydrogen peroxide. {ECO:0000256|PIRNR:PIRNR038927}.
CC   -!- CATALYTIC ACTIVITY: 2 H(2)O(2) = O(2) + 2 H(2)O.
CC       {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498}.
CC   -!- COFACTOR:
CC       Name=heme; Xref=ChEBI:CHEBI:30413;
CC         Evidence={ECO:0000256|PIRNR:PIRNR038927,
CC         ECO:0000256|PIRSR:PIRSR038927-2};
CC   -!- SIMILARITY: Belongs to the catalase family.
CC       {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|RuleBase:RU000498}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP002271; ADO71963.1; -; Genomic_DNA.
DR   EMBL; AAMD01000141; EAU63865.1; -; Genomic_DNA.
DR   RefSeq; WP_002617206.1; NZ_AAMD01000141.1.
DR   STRING; 378806.STAUR_4181; -.
DR   PeroxiBase; 6291; SauKat01.
DR   EnsemblBacteria; ADO71963; ADO71963; STAUR_4181.
DR   EnsemblBacteria; EAU63865; EAU63865; STIAU_6374.
DR   KEGG; sur:STAUR_4181; -.
DR   PATRIC; fig|378806.16.peg.2789; -.
DR   eggNOG; ENOG4105CH6; Bacteria.
DR   eggNOG; COG0753; LUCA.
DR   KO; K03781; -.
DR   OMA; VMWQMSD; -.
DR   OrthoDB; POG091H0424; -.
DR   BioCyc; SAUR378806:G1GOG-4199-MONOMER; -.
DR   Proteomes; UP000001351; Chromosome.
DR   Proteomes; UP000032702; Unassembled WGS sequence.
DR   GO; GO:0004096; F:catalase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0020037; F:heme binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0042744; P:hydrogen peroxide catabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006979; P:response to oxidative stress; IEA:InterPro.
DR   Gene3D; 2.40.180.10; -; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   InterPro; IPR018028; Catalase.
DR   InterPro; IPR024708; Catalase_AS.
DR   InterPro; IPR024712; Catalase_clade2.
DR   InterPro; IPR011614; Catalase_core.
DR   InterPro; IPR037060; Catalase_core_sf.
DR   InterPro; IPR002226; Catalase_haem_BS.
DR   InterPro; IPR010582; Catalase_immune_responsive.
DR   InterPro; IPR020835; Catalase_sf.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR002818; DJ-1/PfpI.
DR   PANTHER; PTHR42821; PTHR42821; 1.
DR   Pfam; PF00199; Catalase; 1.
DR   Pfam; PF06628; Catalase-rel; 1.
DR   Pfam; PF01965; DJ-1_PfpI; 1.
DR   PIRSF; PIRSF038927; Catalase_clade2; 1.
DR   PRINTS; PR00067; CATALASE.
DR   SMART; SM01060; Catalase; 1.
DR   SUPFAM; SSF52317; SSF52317; 1.
DR   SUPFAM; SSF56634; SSF56634; 1.
DR   PROSITE; PS00437; CATALASE_1; 1.
DR   PROSITE; PS00438; CATALASE_2; 1.
DR   PROSITE; PS51402; CATALASE_3; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000001351,
KW   ECO:0000313|Proteomes:UP000032702};
KW   Heme {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|PIRSR:PIRSR038927-3,
KW   ECO:0000256|RuleBase:RU000498};
KW   Hydrogen peroxide {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498};
KW   Iron {ECO:0000256|PIRNR:PIRNR038927, ECO:0000256|PIRSR:PIRSR038927-2,
KW   ECO:0000256|RuleBase:RU000498};
KW   Metal-binding {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|PIRSR:PIRSR038927-2, ECO:0000256|RuleBase:RU000498};
KW   Oxidoreductase {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498, ECO:0000313|EMBL:EAU63865.1};
KW   Peroxidase {ECO:0000256|PIRNR:PIRNR038927,
KW   ECO:0000256|RuleBase:RU000498, ECO:0000313|EMBL:EAU63865.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000001351}.
FT   DOMAIN       25    413       Catalase. {ECO:0000259|SMART:SM01060}.
FT   ACT_SITE     72     72       {ECO:0000256|PIRSR:PIRSR038927-1}.
FT   ACT_SITE    145    145       {ECO:0000256|PIRSR:PIRSR038927-1}.
FT   METAL       359    359       Iron (heme axial ligand).
FT                                {ECO:0000256|PIRSR:PIRSR038927-2}.
FT   BINDING      69     69       Heme. {ECO:0000256|PIRSR:PIRSR038927-3}.
FT   BINDING     109    109       Heme. {ECO:0000256|PIRSR:PIRSR038927-3}.
FT   BINDING     158    158       Heme. {ECO:0000256|PIRSR:PIRSR038927-3}.
FT   BINDING     355    355       Heme. {ECO:0000256|PIRSR:PIRSR038927-3}.
FT   BINDING     366    366       Heme. {ECO:0000256|PIRSR:PIRSR038927-3}.
SQ   SEQUENCE   691 AA;  76349 MW;  96C82157BE0F275A CRC64;
     MSIDERSKDQ DLARNRSDAT GQYLTTDQGI RVEHTDDSLR AGTRGPTLLE DFHFREKMMR
     FDHERIPERV VHARGAAAHG YFQVYASQAK YTKAAFLQDP SQKTPVFVRF STVAGSRGSA
     DTARDVRGFA VKFYTQEGNF DLVGNNIPVF FIQDGIKFPD VIHAVKPEPH HEMPQAASAH
     DSFWDFVSLV PETAHMIMWV MSDRAIPRSY RMMEGFGVHT FRFVNDQGVS RFVKFHWKPL
     LGVHSLVWDE SQKLAGKDPD YHRRDLWEAI EQGDFPEYEL GVQIIEEADA AKLGVELLDA
     TKLVPEELVP VQRIGKLTLN RNPTNYFSET EQVAYCTANI VPGIDFTDDP LMQARLFSYL
     DTQITRLGGP NFAEIPINRP VAPVHNHQQD GFHRQTINTS RANYHPNSLG GGCPMLASTR
     QGGFAHFPEK LAGEKTRVRS QSFADHFSQA AMFFRSLSAP EQQHVIDALR FELGKVEVKE
     IRKRVVDEIL AKIDGTLAAQ VAQGVGVPAP KAVAPPKSVA DSSPALSMEN TKKDSIKTRR
     IAALVADGVD ATALQALRAE LKRQGAQLKI IAKHLGTVTA AGGQPVEVDK SAVTTASIEY
     DAVFVPGGAV SVETLKRDGD ARHFILEAYR HYKAIGVSKE GVDLLKSCGI DAAAPGIATD
     TGGADAFATA FVDAIKKHRH WDRKDTESTP A
//
DBGET integrated database retrieval system