GenomeNet

Database: UniProt/TrEMBL
Entry: Q9KMS0_VIBCH
LinkDB: Q9KMS0_VIBCH
Original site: Q9KMS0_VIBCH 
ID   Q9KMS0_VIBCH            Unreviewed;       466 AA.
AC   Q9KMS0;
DT   01-OCT-2000, integrated into UniProtKB/TrEMBL.
DT   01-OCT-2000, sequence version 1.
DT   20-JUN-2018, entry version 100.
DE   RecName: Full=Alpha-amylase {ECO:0000256|RuleBase:RU361134};
DE            EC=3.2.1.1 {ECO:0000256|RuleBase:RU361134};
GN   OrderedLocusNames=VC_A0250 {ECO:0000313|EMBL:AAF96161.1};
OS   Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales;
OC   Vibrionaceae; Vibrio.
OX   NCBI_TaxID=243277 {ECO:0000313|EMBL:AAF96161.1, ECO:0000313|Proteomes:UP000000584};
RN   [1] {ECO:0000313|EMBL:AAF96161.1, ECO:0000313|Proteomes:UP000000584}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 39315 / El Tor Inaba N16961
RC   {ECO:0000313|Proteomes:UP000000584};
RX   PubMed=10952301; DOI=10.1038/35020000;
RA   Heidelberg J.F., Eisen J.A., Nelson W.C., Clayton R.A., Gwinn M.L.,
RA   Dodson R.J., Haft D.H., Hickey E.K., Peterson J.D., Umayam L.A.,
RA   Gill S.R., Nelson K.E., Read T.D., Tettelin H., Richardson D.,
RA   Ermolaeva M.D., Vamathevan J., Bass S., Qin H., Dragoi I., Sellers P.,
RA   McDonald L., Utterback T., Fleishmann R.D., Nierman W.C., White O.,
RA   Salzberg S.L., Smith H.O., Colwell R.R., Mekalanos J.J., Venter J.C.,
RA   Fraser C.M.;
RT   "DNA sequence of both chromosomes of the cholera pathogen Vibrio
RT   cholerae.";
RL   Nature 406:477-483(2000).
CC   -!- CATALYTIC ACTIVITY: Endohydrolysis of (1->4)-alpha-D-glucosidic
CC       linkages in polysaccharides containing three or more (1->4)-alpha-
CC       linked D-glucose units. {ECO:0000256|RuleBase:RU361134}.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC       {ECO:0000256|RuleBase:RU361134}.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; AE003853; AAF96161.1; -; Genomic_DNA.
DR   PIR; B82482; B82482.
DR   RefSeq; NP_232648.1; NC_002506.1.
DR   RefSeq; WP_000842853.1; NC_002506.1.
DR   ProteinModelPortal; Q9KMS0; -.
DR   STRING; 243277.VCA0250; -.
DR   CAZy; GH13; Glycoside Hydrolase Family 13.
DR   DNASU; 2612181; -.
DR   EnsemblBacteria; AAF96161; AAF96161; VC_A0250.
DR   GeneID; 2612181; -.
DR   KEGG; vch:VCA0250; -.
DR   PATRIC; fig|243277.26.peg.2883; -.
DR   eggNOG; ENOG4105E54; Bacteria.
DR   eggNOG; COG0366; LUCA.
DR   KO; K01176; -.
DR   OMA; QSWGTDW; -.
DR   BioCyc; VCHO:VCA0250-MONOMER; -.
DR   Proteomes; UP000000584; Chromosome 2.
DR   GO; GO:0004556; F:alpha-amylase activity; ISS:TIGR.
DR   GO; GO:0103025; F:alpha-amylase activity (releasing maltohexaose); IEA:UniProtKB-EC.
DR   GO; GO:0043169; F:cation binding; IEA:InterPro.
DR   GO; GO:0009313; P:oligosaccharide catabolic process; ISS:TIGR.
DR   InterPro; IPR006046; Alpha_amylase.
DR   InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   Pfam; PF00128; Alpha-amylase; 1.
DR   PRINTS; PR00110; ALPHAAMYLASE.
DR   SMART; SM00642; Aamy; 1.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|RuleBase:RU361134};
KW   Complete proteome {ECO:0000313|Proteomes:UP000000584};
KW   Glycosidase {ECO:0000256|RuleBase:RU361134};
KW   Hydrolase {ECO:0000256|RuleBase:RU361134};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000584};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL        1     23       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        24    466       Alpha-amylase. {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5004329756.
FT   DOMAIN       24    382       Aamy. {ECO:0000259|SMART:SM00642}.
SQ   SEQUENCE   466 AA;  52573 MW;  7CABB77330C05D3F CRC64;
     MKSSYVVLCA TFAAASFTSS VQAEAILHAF NWKYADVTAN AAQIAAAGYK KVLISPALKS
     SGNEWWARYQ PQDLRVIDSP LGNKTDLQTL IKTLQDYGVE VYSDVVFNHM ANESWKRSDL
     NYPGSEVLAS YTNQAYYYQQ QKLFGDLSHN LFSQNDFHPE GCITDWGNPG HVQYWRLCGG
     AGDRGLPDLD ANAWVINQQR AYLQALKQMG IRGFRIDAVK HMSQYHIDQV FTPEIISGMH
     VFGEVITSGG QGDGSYDAFL APYLNNTTHA AYDFPLFASI RAAFSYQGSM SQLHDPQAYG
     QALPNARAIT FAITHDIPTN DGFRYQILNP QDEQLAYAYL LGKDGGTPLI YSDDLADHED
     KDNGRWANVW NQPSMQHMLR FHNAMQGKPM TVMYSDSCLM LFKRGKEGVV GINKCGESKN
     VTIDTYQHEF NWYQTYQDTL SDDRFSVSSR YHTLTIPARV ARMWML
//
DBGET integrated database retrieval system