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Database: UniProt/TrEMBL
Entry: R0FP98_9BRAS
LinkDB: R0FP98_9BRAS
Original site: R0FP98_9BRAS 
ID   R0FP98_9BRAS            Unreviewed;       484 AA.
AC   R0FP98;
DT   26-JUN-2013, integrated into UniProtKB/TrEMBL.
DT   26-JUN-2013, sequence version 1.
DT   20-JUN-2018, entry version 24.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   ORFNames=CARUB_v10017115mg {ECO:0000313|EMBL:EOA23901.1};
OS   Capsella rubella.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae;
OC   Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae;
OC   Capsella.
OX   NCBI_TaxID=81985 {ECO:0000313|EMBL:EOA23901.1, ECO:0000313|Proteomes:UP000029121};
RN   [1] {ECO:0000313|Proteomes:UP000029121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Monte Gargano {ECO:0000313|Proteomes:UP000029121};
RX   PubMed=23749190; DOI=10.1038/ng.2669;
RA   Slotte T., Hazzouri K.M., Agren J.A., Koenig D., Maumus F., Guo Y.L.,
RA   Steige K., Platts A.E., Escobar J.S., Newman L.K., Wang W.,
RA   Mandakova T., Vello E., Smith L.M., Henz S.R., Steffen J., Takuno S.,
RA   Brandvain Y., Coop G., Andolfatto P., Hu T.T., Blanchette M.,
RA   Clark R.M., Quesneville H., Nordborg M., Gaut B.S., Lysak M.A.,
RA   Jenkins J., Grimwood J., Chapman J., Prochnik S., Shu S., Rokhsar D.,
RA   Schmutz J., Weigel D., Wright S.I.;
RT   "The Capsella rubella genome and the genomic consequences of rapid
RT   mating system evolution.";
RL   Nat. Genet. 45:831-835(2013).
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
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DR   EMBL; KB870809; EOA23901.1; -; Genomic_DNA.
DR   RefSeq; XP_006291003.1; XM_006290941.1.
DR   GeneID; 17885786; -.
DR   KEGG; crb:17885786; -.
DR   KO; K00627; -.
DR   Proteomes; UP000029121; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   GO; GO:0008152; P:metabolic process; IEA:InterPro.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 4.10.320.10; -; 1.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 1.
DR   SUPFAM; SSF47005; SSF47005; 1.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
DR   PROSITE; PS51826; PSBD; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000029121};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029121};
KW   Transferase {ECO:0000256|RuleBase:RU003423}.
FT   DOMAIN       55    133       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      188    225       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   COILED      129    149       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   484 AA;  50245 MW;  F6EBC230625A7021 CRC64;
     MAVSSSSFLS TASLTNSKSN ISFASSVSPS IRSVVFRSSI PPSSHRRVMT VRSKIREIFM
     PALSSTMTEG KIVSWIKTEG EKLAKGESVV VVESDKADMD VETFYDGYLA AIVVGEGETA
     PVGAAIGLLA ETEAEIEEAK TKAASKSSSS PAAEAVVPSP PPVTSSPAPA IAQPAPVTAV
     ADGPRKTVAT PYAKKLAKQH KVDIGSIAGT GPFGRITASD VETAAGIAPS KSSVAPPPPP
     PPPAAATGKA TTATNLPPLL PGSSIVPFTA MQSAVSKNMI ESLSVPTFRV GYPVNTDALD
     ALYQKLKAKG VSMTALLAKA AGMALAQHPV VNASCKDGKS FSYNSNINIA VAVAINGGLI
     TPVLQDADKL DLYLLSQKWK DLVSKARSKQ LQPHEYNSGT FTLSNLGMYG VDRFDAILPP
     GQGAIMAVGA SKPTVVADKD GFFSVKNTML VNVTADHRIV YGADLASFLQ TFAKIVENPD
     SLTL
//
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