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Database: UniProt/TrEMBL
Entry: S5HFF0_SALET
LinkDB: S5HFF0_SALET
Original site: S5HFF0_SALET 
ID   S5HFF0_SALET            Unreviewed;       346 AA.
AC   S5HFF0;
DT   16-OCT-2013, integrated into UniProtKB/TrEMBL.
DT   16-OCT-2013, sequence version 1.
DT   22-NOV-2017, entry version 18.
DE   RecName: Full=Aldose 1-epimerase {ECO:0000256|PIRNR:PIRNR005096};
DE            EC=5.1.3.3 {ECO:0000256|PIRNR:PIRNR005096};
DE   AltName: Full=Galactose mutarotase {ECO:0000256|PIRNR:PIRNR005096};
GN   Name=galM {ECO:0000313|EMBL:AGQ72584.1};
GN   ORFNames=CFSAN002050_10420 {ECO:0000313|EMBL:AGQ72584.1};
OS   Salmonella enterica subsp. enterica serovar Cubana str. CFSAN002050.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=1271863 {ECO:0000313|EMBL:AGQ72584.1, ECO:0000313|Proteomes:UP000014943};
RN   [1] {ECO:0000313|EMBL:AGQ72584.1, ECO:0000313|Proteomes:UP000014943}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFSAN002050 {ECO:0000313|EMBL:AGQ72584.1,
RC   ECO:0000313|Proteomes:UP000014943};
RA   Strain E.A., Allard M.W., Payne J., Timme R.;
RL   Submitted (JUN-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:AGQ72584.1, ECO:0000313|Proteomes:UP000014943}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFSAN002050 {ECO:0000313|EMBL:AGQ72584.1,
RC   ECO:0000313|Proteomes:UP000014943};
RA   Timme R.E., Allard M., Strain E., Brown E.;
RT   "Rapid genome closure with Pacific Biosystems technology.";
RL   Submitted (JUL-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Converts alpha-aldose to the beta-anomer.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- CATALYTIC ACTIVITY: Alpha-D-glucose = beta-D-glucose.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- PATHWAY: Carbohydrate metabolism; hexose metabolism.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
CC   -!- SIMILARITY: Belongs to the aldose epimerase family.
CC       {ECO:0000256|PIRNR:PIRNR005096}.
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DR   EMBL; CP006055; AGQ72584.1; -; Genomic_DNA.
DR   RefSeq; WP_000931428.1; NC_021818.1.
DR   ProteinModelPortal; S5HFF0; -.
DR   EnsemblBacteria; AGQ72584; AGQ72584; CFSAN002050_10420.
DR   KEGG; seec:CFSAN002050_10420; -.
DR   PATRIC; fig|1271863.3.peg.1821; -.
DR   KO; K01785; -.
DR   UniPathway; UPA00242; -.
DR   Proteomes; UP000014943; Chromosome.
DR   GO; GO:0004034; F:aldose 1-epimerase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   GO; GO:0006012; P:galactose metabolic process; IEA:InterPro.
DR   Gene3D; 2.70.98.10; -; 1.
DR   InterPro; IPR018052; Ald1_epimerase_CS.
DR   InterPro; IPR013458; Ald_epimerase_bac.
DR   InterPro; IPR015443; Aldose_1-epimerase.
DR   InterPro; IPR008183; Aldose_1/G6P_1-epimerase.
DR   InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR   InterPro; IPR014718; GH-type_carb-bd.
DR   Pfam; PF01263; Aldose_epim; 1.
DR   PIRSF; PIRSF005096; GALM; 1.
DR   SUPFAM; SSF74650; SSF74650; 1.
DR   TIGRFAMs; TIGR02636; galM_Leloir; 1.
DR   PROSITE; PS00545; ALDOSE_1_EPIMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|PIRNR:PIRNR005096};
KW   Complete proteome {ECO:0000313|Proteomes:UP000014943};
KW   Isomerase {ECO:0000256|PIRNR:PIRNR005096,
KW   ECO:0000313|EMBL:AGQ72584.1}.
FT   ACT_SITE    175    175       Proton donor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   ACT_SITE    309    309       Proton acceptor. {ECO:0000256|PIRSR:
FT                                PIRSR005096-1}.
FT   BINDING     245    245       Substrate. {ECO:0000256|PIRSR:
FT                                PIRSR005096-2}.
SQ   SEQUENCE   346 AA;  38547 MW;  990137870BC8F60A CRC64;
     MLNETPALAP DGQPYRLLTL RNSAGMVVTL MDWGATLLSA RIPLSDGSVR EALLGCASPE
     HYPEQTSFLG ASIGRYANRI ANSRYTFAGE TVQLSPSQGE NQLHGGPEGF DKRRWQIVNQ
     NDRQVLFALT SDDGDQGFPG HLCATAQYRL TDDNRISITY RATVDKPCPV NLTNHVYFNL
     DGDRTDVRQH KLQILADEYL PVDESGIPRQ GLKSVANTSF DFRMPKVIAS EFLADDDQRK
     VKGYDHAFLL QTQGDGKKPA ARLWSQDGKL QMMVYTTAPA LQFYSGNYLA GTPSRGPEPY
     ADWQGLALES ELLPDSPNHP EWPQPDCILR PGEEYASLTE YQFIPF
//
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