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Database: UniProt/TrEMBL
Entry: U3BG03_CALJA
LinkDB: U3BG03_CALJA
Original site: U3BG03_CALJA 
ID   U3BG03_CALJA            Unreviewed;       883 AA.
AC   U3BG03; F7B3M6;
DT   13-NOV-2013, integrated into UniProtKB/TrEMBL.
DT   13-NOV-2013, sequence version 1.
DT   20-JUN-2018, entry version 26.
DE   RecName: Full=Histone-lysine N-methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00903};
DE            EC=2.1.1.43 {ECO:0000256|PROSITE-ProRule:PRU00903};
GN   Name=SUV420H1 {ECO:0000313|EMBL:JAB05202.1};
GN   Synonyms=KMT5B {ECO:0000313|Ensembl:ENSCJAP00000028971};
OS   Callithrix jacchus (White-tufted-ear marmoset).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Platyrrhini; Cebidae; Callitrichinae; Callithrix; Callithrix.
OX   NCBI_TaxID=9483 {ECO:0000313|EMBL:JAB05202.1};
RN   [1] {ECO:0000313|Ensembl:ENSCJAP00000028971, ECO:0000313|Proteomes:UP000008225}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.;
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSCJAP00000028971}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JUN-2011) to UniProtKB.
RN   [3] {ECO:0000313|EMBL:JAB05202.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Bladder {ECO:0000313|EMBL:JAB05202.1}, Cerebellum
RC   {ECO:0000313|EMBL:JAB51208.1}, Cerebral cortex
RC   {ECO:0000313|EMBL:JAB32747.1}, Hippocampus
RC   {ECO:0000313|EMBL:JAB20380.1}, and Skeletal muscle
RC   {ECO:0000313|EMBL:JAB36571.1};
RX   PubMed=25243066; DOI=10.1186/2047-217X-3-14;
RA   Maudhoo M.D., Ren D., Gradnigo J.S., Gibbs R.M., Lubker A.C.,
RA   Moriyama E.N., French J.A., Norgren R.B.Jr.;
RT   "De novo assembly of the common marmoset transcriptome from NextGen
RT   mRNA sequences.";
RL   Gigascience 3:14-14(2014).
CC   -!- CATALYTIC ACTIVITY: S-adenosyl-L-methionine + L-lysine-[histone] =
CC       S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
CC       {ECO:0000256|PROSITE-ProRule:PRU00903}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding
CC       methyltransferase superfamily. Histone-lysine methyltransferase
CC       family. Suvar4-20 subfamily. {ECO:0000256|PROSITE-
CC       ProRule:PRU00903}.
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DR   EMBL; GAMT01006659; JAB05202.1; -; mRNA.
DR   EMBL; GAMS01002756; JAB20380.1; -; mRNA.
DR   EMBL; GAMR01001185; JAB32747.1; -; mRNA.
DR   EMBL; GAMQ01005280; JAB36571.1; -; mRNA.
DR   EMBL; GAMP01001547; JAB51208.1; -; mRNA.
DR   RefSeq; XP_009006857.1; XM_009008609.2.
DR   STRING; 9483.ENSCJAP00000028971; -.
DR   Ensembl; ENSCJAT00000030613; ENSCJAP00000028971; ENSCJAG00000015727.
DR   GeneID; 100400804; -.
DR   KEGG; cjc:100400804; -.
DR   CTD; 51111; -.
DR   eggNOG; KOG2589; Eukaryota.
DR   eggNOG; ENOG410XPH8; LUCA.
DR   GeneTree; ENSGT00520000055640; -.
DR   KO; K11429; -.
DR   OMA; SGCLTRH; -.
DR   OrthoDB; EOG091G0IUY; -.
DR   TreeFam; TF106433; -.
DR   Proteomes; UP000008225; Unplaced.
DR   GO; GO:0000780; C:condensed nuclear chromosome, centromeric region; IEA:Ensembl.
DR   GO; GO:0042799; F:histone methyltransferase activity (H4-K20 specific); IEA:UniProtKB-UniRule.
DR   GO; GO:0034773; P:histone H4-K20 trimethylation; IEA:UniProtKB-UniRule.
DR   InterPro; IPR025790; Hist-Lys_N-MTase_Suvar4-20.
DR   InterPro; IPR001214; SET_dom.
DR   Pfam; PF00856; SET; 1.
DR   SMART; SM00317; SET; 1.
DR   PROSITE; PS51570; SAM_MT43_SUVAR420_2; 1.
DR   PROSITE; PS50280; SET; 1.
PE   2: Evidence at transcript level;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008225};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU00903,
KW   ECO:0000313|EMBL:JAB05202.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008225};
KW   S-adenosyl-L-methionine {ECO:0000256|PROSITE-ProRule:PRU00903};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU00903,
KW   ECO:0000313|EMBL:JAB05202.1}.
FT   DOMAIN      193    308       SET. {ECO:0000259|PROSITE:PS50280}.
SQ   SEQUENCE   883 AA;  98851 MW;  7ADA8D0AFCBB9A4B CRC64;
     MKWLGESKNM VVNGRRNGGK LSNDHQQNQS KLQHAGKDTL KAGKNAVERR SSRCNGNSGF
     EGQSRYVPSS GMSAKELCEN DDLATSLVLD PYLGFQTHKM NTSAFPSRSS RHFSKSDSFS
     HNNPVRFRPI KGRQEELKEV IERFKKDEHL EKAFKCLTSG EWARHYFLNK NKMQEKLFKE
     HVFIYLRMFA TDSGFEILPC NRYSSEQNGA KIVATKEWKR NDKIELLVGC IAELSEIEEN
     MLLRHGENDF SVMYSTRKNC AQLWLGPAAF INHDCRPNCK FVSTGRDTAC VKALRDIEPG
     EEISCYYGDG FFGENNEFCE CYTCERRGTG AFKSRVGLPA PAPVINSKYG LRETDKRLNR
     LKKLGDSSKN SDSQSVSSNT DADTTQEQNN ATSNRKSSVG VKKNSKSRTL TRQSMSRIPA
     SSNSTSSKLT HINNSRVPKK LKKPAKPLLS KIKLRNHCKR LEQKNASRKL EMGNLVLKEP
     KVVLYKNLPI KKDKEPEGPA QAAVASGCLT RHAAREHRQN PVRGAHLQGE GSPCTYITRR
     SVRTRTTLKE ASDIKLEPNT LDGYKGSVTE PCPDSDEQPA PVVQEEELAH ETAQNGEAKC
     HKSDTGMSKK KSRQGKLVKQ FAKIEESTPE HDSPGKDDTV PDLMGPHSDQ GEHSGTVGVP
     VSYTDCAPSP VGCSVVTSDS FKTKDSFRTA KSKKKRRITR YDAQLILENN SGIPKLTLRR
     RHDSSSKTND QENDGMNSSK ISIKLSKDHD NDSNLYVAKL NNGFNSGSGS SSTKLKIQLK
     RDEESRGSYT EGLHENGVCC SDPLSLLESR MEVDDYSQYE EESTDDSSSS EGDDEDDDYD
     DDFEDDFIPL PPAKRLRLIV GKDSIDIDIS SRRREDQSLR LNA
//
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