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Database: UniProt/TrEMBL
Entry: W9BMV5_KLEPN
LinkDB: W9BMV5_KLEPN
Original site: W9BMV5_KLEPN 
ID   W9BMV5_KLEPN            Unreviewed;       421 AA.
AC   W9BMV5;
DT   14-MAY-2014, integrated into UniProtKB/TrEMBL.
DT   14-MAY-2014, sequence version 1.
DT   20-JUN-2018, entry version 47.
DE   SubName: Full=4-aminobutyrate aminotransferase PuuE {ECO:0000313|EMBL:KMW83988.1};
DE   SubName: Full=4-aminobutyrate--2-oxoglutarate transaminase {ECO:0000313|EMBL:AUA48949.1};
DE   SubName: Full=Aspartate aminotransferase family protein {ECO:0000313|EMBL:AUY68017.1};
DE            EC=2.6.1.19 {ECO:0000313|EMBL:ALR25607.1, ECO:0000313|EMBL:AUA48949.1, ECO:0000313|EMBL:OXT24760.1};
GN   ORFNames=AGG09_15685 {ECO:0000313|EMBL:ALR25607.1}, B1727_04730
GN   {ECO:0000313|EMBL:OXT24760.1}, B4U22_28785
GN   {ECO:0000313|EMBL:OWF99707.1}, B4U36_26725
GN   {ECO:0000313|EMBL:PLB91548.1}, BKY56_026120
GN   {ECO:0000313|EMBL:AUY68017.1}, BL124_0007355
GN   {ECO:0000313|EMBL:OSU24532.1}, BN49_0292
GN   {ECO:0000313|EMBL:CDO12060.1}, BVX91_06685
GN   {ECO:0000313|EMBL:PAX13723.1}, C3483_01485
GN   {ECO:0000313|EMBL:AVB70107.1}, C9J88_02095
GN   {ECO:0000313|EMBL:AVS24871.1}, CWQ24_01525
GN   {ECO:0000313|EMBL:AUA48949.1}, SM57_04067
GN   {ECO:0000313|EMBL:KMW83988.1};
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella.
OX   NCBI_TaxID=573 {ECO:0000313|EMBL:CDO12060.1, ECO:0000313|Proteomes:UP000032739};
RN   [1] {ECO:0000313|EMBL:CDO12060.1, ECO:0000313|Proteomes:UP000032739}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CIP 52.145 {ECO:0000313|Proteomes:UP000032739}, and Kp52.145
RC   {ECO:0000313|EMBL:CDO12060.1};
RX   PubMed=25341126; DOI=10.3201/eid2011.140206;
RA   Bialek-Davenet S., Criscuolo A., Ailloud F., Passet V., Jones L.,
RA   Delannoy-Vieillard A.S., Garin B., Le Hello S., Arlet G.,
RA   Nicolas-Chanoine M.H., Decr D., Brisse S.;
RT   "Genomic Definition of Hypervirulent and Multidrug-Resistant
RT   Klebsiella pneumoniae Clonal Groups.";
RL   Emerg. Infect. Dis. 20:1812-1820(2014).
RN   [2] {ECO:0000313|EMBL:KMW83988.1, ECO:0000313|Proteomes:UP000037134}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MGH83 {ECO:0000313|EMBL:KMW83988.1,
RC   ECO:0000313|Proteomes:UP000037134};
RG   The Broad Institute Genomics Platform;
RG   The Broad Institute Genome Sequencing Center for Infectious Disease;
RA   Earl A.M., Onderdonk A.B., Kirby J., Ferraro M.J., Huang S.,
RA   Spencer M., Fodor A., Hooper D., Dekker J., O'Brien T., Quan V.,
RA   Gombosev A., Delaney M., Dubois A., Ernst C., Kim D.S., Rossman W.,
RA   Gohs F., Petruso H., Nozar T., Mougeot F., Manson-Mcguire A.,
RA   Young S., Abouelleil A., Cao P., Chapman S.B., Griggs A., Priest M.,
RA   Shea T., Wortman I., Wortman J.R., Nusbaum C., Birren B.;
RT   "The Genome Sequence of None.";
RL   Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Proteomes:UP000067608}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CAV1193 {ECO:0000313|Proteomes:UP000067608};
RA   Sheppard A.E., Stoesser N., Sebra R., Kasarskis A., Deikus G.,
RA   Anson L., Walker A.S., Peto T.E., Crook D.W., Mathers A.J.;
RT   "Complete Genome Sequence of the KPC-producing Klebsiella pneumoniae
RT   strain CAV1193.";
RL   Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
RN   [4] {ECO:0000313|EMBL:AUY68017.1, ECO:0000313|Proteomes:UP000186509}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=GN-2 {ECO:0000313|EMBL:AUY68017.1,
RC   ECO:0000313|Proteomes:UP000186509};
RX   PubMed=27965935;
RA   Ye M., Tu J., Jiang J., Bi Y., You W., Zhang Y., Ren J., Zhu T.,
RA   Cao Z., Yu Z., Shao C., Shen Z., Ding B., Yuan J., Zhao X., Guo Q.,
RA   Xu X., Huang J., Wang M.;
RT   "Clinical and Genomic Analysis of Liver Abscess-Causing Klebsiella
RT   pneumoniae Identifies New Liver Abscess-Associated Virulence Genes.";
RL   Front. Cell. Infect. Microbiol. 6:165-165(2016).
RN   [5] {ECO:0000313|EMBL:ALR25607.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=CAV1193 {ECO:0000313|EMBL:ALR25607.1};
RX   PubMed=26823590;
RA   Sheppard A.E., Stoesser N., Sebra R., Kasarskis A., Deikus G.,
RA   Anson L., Walker A.S., Peto T.E., Crook D.W., Mathers A.J.;
RT   "Complete Genome Sequence of KPC-Producing Klebsiella pneumoniae
RT   Strain CAV1193.";
RL   Genome Announc. 4:e01649-15(2016).
RN   [6] {ECO:0000313|EMBL:AUY68017.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=GN-2 {ECO:0000313|EMBL:AUY68017.1};
RA   Mah S.A., Swanson W.J., Moy G.W., Vacquier V.D.;
RL   Submitted (JAN-2017) to the EMBL/GenBank/DDBJ databases.
RN   [7] {ECO:0000313|EMBL:OXT24760.1, ECO:0000313|Proteomes:UP000215037}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OK8 {ECO:0000313|EMBL:OXT24760.1,
RC   ECO:0000313|Proteomes:UP000215037};
RA   Nagamalleswari E., Nagaraja V.;
RT   "Draft genome analysis of Klebsiella pneumoniae OK8.";
RL   Submitted (MAR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [8] {ECO:0000313|EMBL:OWF99707.1, ECO:0000313|Proteomes:UP000196744}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1830 {ECO:0000313|EMBL:OWF99707.1,
RC   ECO:0000313|Proteomes:UP000196744};
RA   Martins R.C., Perdigao-Neto L.V., Costa S.F., Levin A.S.;
RT   "Klebsiella pneumoniae genome sequencing and assembly.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [9] {ECO:0000313|EMBL:OSU24532.1, ECO:0000313|Proteomes:UP000186691}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1163_2046 {ECO:0000313|EMBL:OSU24532.1,
RC   ECO:0000313|Proteomes:UP000186691};
RA   Afonso C.L., Miller P.J., Scott M.A., Spackman E., Goraichik I.,
RA   Dimitrov K.M., Suarez D.L., Swayne D.E.;
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
RN   [10] {ECO:0000313|EMBL:PAX13723.1, ECO:0000313|Proteomes:UP000218240}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WBB417 {ECO:0000313|EMBL:PAX13723.1,
RC   ECO:0000313|Proteomes:UP000218240};
RA   Koh T.H., Abdul Rahman N., Teo J.W., La M.-V., Periaswamy B.,
RA   Chen S.L.;
RT   "Draft Genome Sequence of a Singapore Klebsiella pneumoniae subsp.
RT   pnuemoniae isolate DS32358_14 Encoding the Carbapenemase Gene blaVIM-
RT   1.";
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
RN   [11] {ECO:0000313|EMBL:AUA48949.1, ECO:0000313|Proteomes:UP000232092}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NU-CRE047 {ECO:0000313|EMBL:AUA48949.1,
RC   ECO:0000313|Proteomes:UP000232092};
RA   Ozer E.A., Krapp F., Qi C., Hauser A.R.;
RT   "Complete genome sequence of Klebsiella pneumoniae strain NU-CRE047.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN   [12] {ECO:0000313|EMBL:PLB91548.1, ECO:0000313|Proteomes:UP000234277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LIM1499 {ECO:0000313|EMBL:PLB91548.1,
RC   ECO:0000313|Proteomes:UP000234277};
RA   Martins R.C.R., Perdigao-Neto L.V., Costa S.F., Levin A.S.S.;
RT   "Klebsiella pneumoniae genome sequencing and assembly.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [13] {ECO:0000313|EMBL:AVB70107.1, ECO:0000313|Proteomes:UP000238332}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NUHL30457 {ECO:0000313|EMBL:AVB70107.1,
RC   ECO:0000313|Proteomes:UP000238332};
RA   Liu Y.;
RT   "Genome of Klebsiella pneumoniae NUHL3069.";
RL   Submitted (FEB-2018) to the EMBL/GenBank/DDBJ databases.
RN   [14] {ECO:0000313|EMBL:AVS24871.1, ECO:0000313|Proteomes:UP000241666}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFSAN054110 {ECO:0000313|EMBL:AVS24871.1,
RC   ECO:0000313|Proteomes:UP000241666};
RA   Hoffmann M., Pedersen S.K., Sanchez M., Pettengill J.B.,
RA   Hendriksen R.S.;
RT   "Genome assemblies for Global Microbial Identifier (GMI) Proficiency
RT   Testing reference strains.";
RL   Submitted (MAR-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the class-III pyridoxal-phosphate-dependent
CC       aminotransferase family. {ECO:0000256|RuleBase:RU003560}.
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DR   EMBL; CP013322; ALR25607.1; -; Genomic_DNA.
DR   EMBL; CP025037; AUA48949.1; -; Genomic_DNA.
DR   EMBL; CP019160; AUY68017.1; -; Genomic_DNA.
DR   EMBL; CP026586; AVB70107.1; -; Genomic_DNA.
DR   EMBL; CP028180; AVS24871.1; -; Genomic_DNA.
DR   EMBL; FO834906; CDO12060.1; -; Genomic_DNA.
DR   EMBL; LGJJ01000013; KMW83988.1; -; Genomic_DNA.
DR   EMBL; MPYG03000060; OSU24532.1; -; Genomic_DNA.
DR   EMBL; NBSB01001899; OWF99707.1; -; Genomic_DNA.
DR   EMBL; MZXR01000041; OXT24760.1; -; Genomic_DNA.
DR   EMBL; NSMB01000004; PAX13723.1; -; Genomic_DNA.
DR   EMBL; PKRL01002391; PLB91548.1; -; Genomic_DNA.
DR   RefSeq; WP_002920814.1; NZ_PQKJ01000011.1.
DR   EnsemblBacteria; ALR25607; ALR25607; AGG09_15685.
DR   EnsemblBacteria; CDO12060; CDO12060; BN49_0292.
DR   KEGG; kpb:FH42_15460; -.
DR   KEGG; kpne:KU54_001485; -.
DR   KEGG; kpnk:BN49_0292; -.
DR   KEGG; kpnu:LI86_01480; -.
DR   PATRIC; fig|573.1347.peg.2677; -.
DR   eggNOG; ENOG4108JPW; Bacteria.
DR   eggNOG; COG0160; LUCA.
DR   KO; K00823; -.
DR   Proteomes; UP000032739; Chromosome.
DR   Proteomes; UP000037134; Unassembled WGS sequence.
DR   Proteomes; UP000067608; Chromosome.
DR   Proteomes; UP000186509; Chromosome.
DR   Proteomes; UP000186691; Unassembled WGS sequence.
DR   Proteomes; UP000196744; Unassembled WGS sequence.
DR   Proteomes; UP000215037; Unassembled WGS sequence.
DR   Proteomes; UP000218240; Unassembled WGS sequence.
DR   Proteomes; UP000232092; Chromosome.
DR   Proteomes; UP000234277; Unassembled WGS sequence.
DR   Proteomes; UP000238332; Chromosome.
DR   Proteomes; UP000241666; Chromosome.
DR   GO; GO:0034386; F:4-aminobutyrate:2-oxoglutarate transaminase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
DR   GO; GO:0009448; P:gamma-aminobutyric acid metabolic process; IEA:InterPro.
DR   CDD; cd00610; OAT_like; 1.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 2.
DR   InterPro; IPR004632; 4NH2But_aminotransferase_bac.
DR   InterPro; IPR005814; Aminotrans_3.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_dom1.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   Pfam; PF00202; Aminotran_3; 1.
DR   PIRSF; PIRSF000521; Transaminase_4ab_Lys_Orn; 2.
DR   SUPFAM; SSF53383; SSF53383; 1.
DR   TIGRFAMs; TIGR00700; GABAtrnsam; 1.
DR   PROSITE; PS00600; AA_TRANSFER_CLASS_3; 1.
PE   3: Inferred from homology;
KW   Aminotransferase {ECO:0000313|EMBL:ALR25607.1};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032739,
KW   ECO:0000313|Proteomes:UP000037134, ECO:0000313|Proteomes:UP000067608,
KW   ECO:0000313|Proteomes:UP000186509};
KW   Pyridoxal phosphate {ECO:0000256|RuleBase:RU003560};
KW   Transferase {ECO:0000313|EMBL:ALR25607.1}.
SQ   SEQUENCE   421 AA;  44926 MW;  3B1F5D8016FDD5A5 CRC64;
     MKSSELNQRR QQATPRGVGV MCNYFVEKAE NATLWDIEGN EVIDFAAGIA VLNTGHRHPK
     VVAAVADQLQ AFTHTAYQIV PYESYVSLAE RINDLAPIDG PAKTAFFTTG AEAVENAVKI
     ARAYTGRPGL ITFGGGFHGR TFMTMALTGK VAPYKIGFGP FPGSVYHGVY PNAAHGVTTA
     DALKSLERIF KADIAPDQVA AIILEPIQGE GGFNVAPADF MQALRDLCDT HGILLIADEV
     QTGFARTGKL FAMQHYEVKP DLMTMAKSLA GGFPLSGVVG RAEVMDAPAP GGLGGTYAGN
     PLAVAAAHAV LDVIAEEQLC QRAEQLGSHL QEVLNQARAT CPAIVDVRGR GSMVAVEFND
     PQTGEPSPEF TRLVQQKAQE NGLLLLSCGV YGNVIRFLYP LTIPDAQFSK ALDILARVLK
     S
//
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