KEGG   Trichinella spiralis: Tsp_00651
Entry
Tsp_00651         CDS       T01609                                 
Name
(RefSeq) c-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
tsp  Trichinella spiralis
Pathway
tsp00670  One carbon pool by folate
tsp01100  Metabolic pathways
tsp01240  Biosynthesis of cofactors
Module
tsp_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:tsp00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Tsp_00651
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tsp04147]
    Tsp_00651
Enzymes [BR:tsp01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     Tsp_00651
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     Tsp_00651
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     Tsp_00651
Exosome [BR:tsp04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   Tsp_00651
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 10903890
NCBI-ProteinID: XP_003376453
Position
Unknown
AA seq 923 aa
MAVLIDGKKIASQLRQKIRDHLSTVKSEFPKFNPKLAIVQVGDRQDSNVYIRNKLKAADE
IGISAQLIKLSSAIGEFELIDRIEKLNMDPDVHGIIVQLPLDASAEIDAEKVINSINFEK
DVDGLTLHNAGRLARGELENTIVPCTPKGCLELLKHTGINISGKHCVVVGRSRIVGGPVS
ALMLWQNATVTTCHSKTANLAEFCQSADILIVAVGRPNLIQGSWIKPRAVVIDCGINVVE
DDEKRLVGDVEFESAKQVASFITPVPGGVGPMTVAMLMSNTVDAACRTLKRVKRWPLTPY
EPVLKSPVPSDLEISYSHKPISIDKLANSIGLLPHEVEQYGKFKAKVSLDVLNRYKEQKN
GSYVIVTSMSPPSRGAGKSTIVIGLTQALNVYLKTNSFACLRQPSQGPTFGMKGGAAGGG
YSQVYFFAYLVVPMDEFNLHLTGDFHAIVAATNLLAAAVETRLFHESTSSTEALYKRLVP
VKHGQRVFTDNQLSRLEKLNIQPKHPDQLNPEEREQFSRLNIDSGTITWNRVVDTNDRFL
RLVTVGQSPSEKGHSRQCRFDIAAASEIAAILALTTGLGDLRRRLGRIVVANDFQGRPVC
ADDLSVAGALTALMKDALRPNLMQTLQGTPVFVHGGPFANIAHGNSSILADWIALKLVGQ
DGVVVTEAGFGADCRTSGLCANVAVVVVTIEALKLHGGAPEPRPTDDSSPDLLAFVENGC
LNMIRHIENIHKFGTPVIVAVNKYSTDTTAELDVVRREALRAGALDVVVCEQWEKGGLGC
VELAEAVSKAVRQPKSTHSFKLLYPDQWSIKEKIETIAKEIYGADGVEFTVDAEKALAKL
TDQGFDKLPVCMAKTQKSFSNDPNWKGVPSGYTLPVRDVRVCAGAGFLYALVGEIQTMPG
LPIRPAFFDIDVDLETEFVKGLF
NT seq 2772 nt   +upstreamnt  +downstreamnt
atggccgttttaattgatggcaaaaagatcgcctcacagttgagacaaaaaattcgagat
catttgtccacagtgaaaagtgaatttccaaaattcaatcccaaactggcaattgtccaa
gttggagaccggcaagattcgaacgtctacatccggaacaagctgaaagcggccgatgaa
attggcatttcagctcagctgatcaaattgtcctctgcaattggggaatttgaactgatc
gaccgaattgaaaagctgaacatggatccggatgttcacggaattattgtccagttgcct
ttggatgcgagcgctgagatcgacgctgagaaagtgatcaacagcatcaattttgaaaaa
gacgtcgatggactgactctgcacaatgctggtcgtttagccaggggggaacttgaaaat
acaattgtcccttgtactccgaaaggatgtttggaattgttgaaacatacaggcatcaat
ataagcggaaaacattgcgtggtggttggacgaagtcgaattgtcggcggacccgtttcg
gctttgatgctctggcaaaatgctacagtaacaacatgccattcgaaaacggcaaatttg
gctgaattttgtcaaagtgctgatattttaatcgttgctgtaggtcgtccgaacttaatt
caaggatcttggattaaaccgagagcagttgtaattgattgcggtataaatgttgtggaa
gacgatgaaaaacgtctcgtaggtgatgtcgaatttgagtcggctaaacaagtggccagt
ttcatcacgccagtacccggtggtgtcgggccgatgacagttgccatgctgatgtcgaat
acagtagacgcagcttgtagaacactgaagcgtgtgaaaaggtggccgctaacgccgtac
gagcctgtgttgaaaagtccggttccgagcgatttggaaatatcctattctcacaaacca
atttccatcgacaaactagcgaattccattggacttttgcctcacgaagtggaacagtac
ggcaaattcaaagccaaagtttctttggatgttttgaatcgttacaaagagcagaaaaat
ggttcctatgtaatcgtcactagcatgtcaccgccatctcgaggggcaggaaaaagtacc
atagtgatcggtttgacgcaagcgttgaacgtctatttgaaaacgaactcattcgcttgt
cttcgtcaaccatcccaagggcctacattcggcatgaaaggcggtgcagccggtggtgga
tattcccaagtatacttctttgcatatttggttgttccgatggatgaattcaatcttcat
ttaactggtgattttcacgcaatcgtcgcggcgaccaatttactggccgccgccgttgaa
acccgcctgtttcacgaatcgacatccagcaccgaagcgctttacaaacgtctggtgccg
gtaaagcatggccaacgagtattcaccgacaatcagttgagtcggttggaaaaattgaac
atccagcccaaacatccggaccagttgaaccccgaagagagggaacaattttccaggctg
aacatcgacagcggaacgatcacgtggaaccgcgtggtcgacaccaacgaccgctttctg
cgcctggtcactgtgggccagtcgccgtcagaaaaaggccacagcagacagtgtcggttc
gatatcgccgccgccagtgaaatcgctgctattctggcgttgaccaccggtctgggcgat
ctgaggcgccgactgggtcggatcgtcgtcgccaacgacttccaagggcggccggtatgc
gccgacgatttgtccgtcgccggtgctctgaccgccctgatgaaagatgcgctgcgtcca
aatttgatgcagacactccaaggtacgcccgtgttcgtccacggcggtccgtttgccaac
atcgcccacggcaacagttccatactggccgattggatcgcgttgaaattggtcggccaa
gacggcgtcgtcgtcactgaagccggcttcggcgcggactgcagaacttccggtttgtgt
gccaacgtcgccgtggtcgtggtcacaattgaggcattgaaattgcacggcggcgcgccg
gaaccacgccccactgacgactcttcgccagatttgttggcattcgtcgaaaacggctgc
ttgaacatgattcggcatattgaaaatatccacaaattcggcacaccggtcatcgtggcc
gtcaacaagtattccaccgacacaacggccgaattggacgtcgtcagacgagaagcgctc
cgagccggcgctttggacgtggtcgtctgcgaacagtgggaaaaaggcggtctgggatgc
gtggaactggccgaagcggtttccaaagctgttcgccaaccaaaatccacccactcgttc
aaacttctctaccctgaccagtggtcaatcaaagaaaaaattgaaaccattgccaaagaa
atttacggtgccgacggggttgaatttacagtcgacgccgaaaaggcgctggccaaattg
accgaccaaggtttcgacaaattgcccgtctgcatggcaaaaacgcaaaaatcattcagc
aacgatccgaattggaaaggcgtgccgtccggatacacgctgccggtcagggatgtgcga
gtttgcgccggggcgggatttctgtacgctctggtgggagaaattcaaacaatgcccggc
ttgccgattcgtccggcttttttcgacattgacgtcgatttggagacggaatttgtcaaa
ggcttgttttga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (22)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (53)   

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