KEGG   Thioalkalivibrio paradoxus: THITH_10805
Entry
THITH_10805       CDS       T03590                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
tti  Thioalkalivibrio paradoxus
Pathway
tti00290  Valine, leucine and isoleucine biosynthesis
tti00620  Pyruvate metabolism
tti01100  Metabolic pathways
tti01110  Biosynthesis of secondary metabolites
tti01210  2-Oxocarboxylic acid metabolism
tti01230  Biosynthesis of amino acids
Module
tti_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:tti00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    THITH_10805
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    THITH_10805
Enzymes [BR:tti01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     THITH_10805
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AHE98654
UniProt: W0DJ86
Position
complement(2319302..2321002)
AA seq 566 aa
MNHPRFDHRKYAPAPVIAKPDRRWPDRRIERAPVFASVDLRDGNQALERPMSVEQKLQFF
DLLVGIGVTEIEVGFPSASQPDFDFTRRLIEEGRIPDHVTIQVLTQAREDLIRRTFEALA
GVPRAIVHVYNSTNPAQREQVFGLDRDGVRRIAENGARWVRDIAAEYPGTDWTFQYSPES
YSATEPDYAVEVVDAVNAIWRPDQGQQVIINLPATVEITTPNVFADQVEWFCDRVAMREH
FVLSLHTHNDRGTGVAAAELGLLAGADRLEGTLFGNGERTGNMDLITVAMNLYSQGIDPK
IDLSEMERIEAVYRECTGLPVHPRHPWAGELVYTAFSGSHQDAIRKGMVHQQRRGGPWQV
PYLPIDPRDLGRHYEAVVRINSQSGKGGVTHVLERDHGITLPRWLAVEFARAVQAAAEAS
GAEVNSRTVHSLFDRLYLATPEAWRLSGYRLNRQGAQVEIDVQLAVDGVVQRLTARGDGV
VSALVSALERRYGVAVEVVEFDEHALEHSTGARALAAVALSVDGTRATGAAIAEDSAGAA
VQAVLTALSRAGVEAAATEPKLAVAT
NT seq 1701 nt   +upstreamnt  +downstreamnt
atgaaccatccgagattcgaccatcgcaagtatgcccccgcaccggtgatcgcgaagccc
gaccggcgctggccggaccggcgcatcgagcgcgctccggtattcgccagcgtcgacctg
cgcgacggcaaccaggcgctcgagcgcccgatgtcggtcgagcagaagctgcaattcttc
gatttgctggtcgggatcggtgtgaccgagatcgaggtgggtttcccgtcggcgtcgcag
ccggatttcgacttcacccggcgcctgatcgaggaaggccggattcccgatcatgtgacg
atccaggtgctgacgcaggcgcgcgaggacctgatccggcgcaccttcgaggccctggcg
ggcgtgccgcgtgcgatcgtgcatgtgtacaactcgaccaacccggcgcagcgcgagcag
gtgttcgggctggaccgcgacggcgtgcgccggatcgcggagaacggcgcgcgctgggtg
cgcgatatcgcggccgagtatcccggcaccgactggaccttccagtactcgcccgagagc
tactcggccaccgagcccgactacgcggtcgaagtggtcgacgcggtgaacgcgatctgg
cggcccgatcagggccagcaggtgatcatcaacctgccggcgacggtcgagatcaccacg
cccaacgtgttcgccgaccaggtcgagtggttctgcgatcgcgtcgcgatgcgcgagcac
ttcgtgctgtcgctgcatacgcacaacgaccgcggcaccggggtcgcggcggccgagctg
gggctgctggcgggggcggaccggctggaagggacattgttcggcaacggcgagcgtacc
gggaacatggacctgatcacagtcgctatgaacttgtactcgcaaggcattgatccgaaa
atcgacttgtcggagatggaacggatcgaggcggtgtaccgcgagtgcaccgggttgccc
gtgcacccgcggcatccctgggccggggaactcgtctacaccgcgttctcgggcagtcac
caggatgcgatccgcaagggcatggtccaccagcagcgtcgcggtggtccctggcaggtg
ccgtacctgccgatcgacccgcgcgatctgggccggcattacgaagcggtggtgcggatc
aacagtcagtccggcaagggcggtgtgacccacgtgctggagcgcgatcacggcatcacc
ttgccgcgctggctggcggtggagttcgcgcgcgcggtgcaggcggcggcggaggcgagc
ggggccgaggtgaactcgcgcacggtgcactcgctgttcgaccggctgtacctggccacc
ccggaagcctggcgtttgagcgggtaccggctgaaccgccaaggtgcgcaggtcgagatc
gacgtgcaactggcggtcgacggcgtggtgcaacgcctgaccgcgcgcggcgatggcgtc
gtttcggcgctggtatcggcgctggagcggcggtacggtgtggcggtcgaggtggtcgag
ttcgacgaacacgcgctggagcacagcaccggtgcgcgggcgctggccgcggttgcgctg
agcgtcgacgggacgcgtgcgaccggtgcggcaatcgcggaggacagtgccggagccgcg
gtgcaggcggtgctgaccgcgctgtcgcgtgcgggggtcgaggccgccgcaacggagccg
aagctcgccgtcgcgacctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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