KEGG   Thermus thermophilus HB8: TTHA0185
Entry
TTHA0185          CDS       T00220                                 
Symbol
TTHA0185
Name
(GenBank) pyruvate dehydrogenase complex, pyruvate dehydrogenase E1 component
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
ttj  Thermus thermophilus HB8
Pathway
ttj00010  Glycolysis / Gluconeogenesis
ttj00020  Citrate cycle (TCA cycle)
ttj00620  Pyruvate metabolism
ttj00785  Lipoic acid metabolism
ttj01100  Metabolic pathways
ttj01110  Biosynthesis of secondary metabolites
ttj01120  Microbial metabolism in diverse environments
ttj01200  Carbon metabolism
ttj01210  2-Oxocarboxylic acid metabolism
Module
ttj_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:ttj00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    TTHA0185 (TTHA0185)
   00020 Citrate cycle (TCA cycle)
    TTHA0185 (TTHA0185)
   00620 Pyruvate metabolism
    TTHA0185 (TTHA0185)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    TTHA0185 (TTHA0185)
Enzymes [BR:ttj01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     TTHA0185 (TTHA0185)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C
Other DBs
NCBI-ProteinID: BAD70008
UniProt: Q5SLV8
Position
1:complement(180308..183025)
AA seq 905 aa
MTEKELKAAFQALSPEEKARFLEIENREWLESLEYVLKVEGPERVEELLRLLDEYLFRHG
VYPANRLSTPYLNTLPKEKEPPYPGDLELERRIANILRWNVAMMVTRANKKADGIGGHIA
TYASIAELYEVGFNHFFRGPEAGLDRDLVFFQGHASPGNYARAFLEGRLKEEDLENFRRE
VHPPVPGGRGLSSYPHPWLMPDFWEFPTVSMGLGPIQAIYQARFMRYLEDRGLKPKSSAK
VWAFLGDGEHDEPETVGALHLAARENLDNLIFVVNCNLQRLDGPVRGNSKVIQELERLYR
GAGWRVIKVVWGSAWDELLAKDKEGHLLRRFEALVDGESQRYAAFGGKELRERFFNTPEL
KKLIEGMTDEELTELTRSRGGHDMVKIYAAYKAAVEHRGSPVVILARTIKGYGMGPTVMA
KNVAHQVKKLTEEDLKEARRFLGIPIPEEKLPELPYYHPGPDSPEVRYLLERRKALGGFV
PERRVRFQGGLEVPEEEFFREFYEGSGGREISTTMAFVRILAKLLRHPKIGKYIVPIVPD
EARTFGMEALIAQVGVYSPQGQLYVPVDAGTLTAYKESQKGQILEEGITEAGAMAEFIAA
GTAYAHWGIPTIPFFITYSMFGLQRIGDLVWAAADQRARGFFLGATAGRTTLAGEGLQHQ
DGQSHVYALAAPNLLAYDPAFAYEFAVILEDGLRRMYGRGEDVFYYITIENENYVHPPMP
EPREKVKEGILKGLYLFRAGEGKGPKVQLFGTGPILNEALKAQELLAKYGVVADVWSATS
YKALYVDAIEAERETRLLGKARRPYVQEALEGHEGPIVAATDYLKALPNLIRGYVDRPFA
VLGTDGFGRSDTREALRDFFEVDARHIAYTALALLHGEGKVTKRTLNQARKDLGLKLEEV
PPHRR
NT seq 2718 nt   +upstreamnt  +downstreamnt
atgacggaaaaggagctgaaggcggccttccaggccctttcgcccgaggagaaggcccgc
ttcctagaaatagagaaccgggagtggctggagtctttggaatacgtcctcaaggtggag
ggccccgagcgggtggaggagctcttgcgccttctggacgagtacctcttccgccatggg
gtctaccccgcaaaccgcctctccaccccctacctcaacaccctccccaaggagaaagag
cccccttaccccggggacctggagctggagcgccgcatcgccaacatcctccgctggaac
gtggccatgatggtcacccgggccaacaagaaggcggacggcatcggggggcacatcgcc
acctacgcctccatcgccgagctttacgaggtgggcttcaaccacttcttccgcgggccg
gaggcggggctggaccgggacctcgtcttcttccagggccacgcctcccccgggaactac
gcccgggcctttttggaggggcggcttaaggaggaggacctggagaacttccgccgcgag
gtccaccccccggtgccggggggccgggggctttccagctacccccacccttggctcatg
cccgacttctgggagttccccacggtctccatgggcctcggccccatccaggccatctac
caggcgcgcttcatgcgctacctcgaggaccgaggcctcaagcccaaaagctccgccaag
gtctgggccttcctcggggacggggagcacgacgagcccgagacggtgggggcgcttcac
ctcgccgcccgggagaacctggacaacctcatcttcgtggtgaactgcaacctccagcgc
ttagacggccccgtgcggggcaactccaaggtcatccaggagctggaaaggctctacagg
ggcgcgggctggcgcgtgatcaaggtggtctggggttcggcctgggacgagctcctcgcc
aaggataaggagggccacctcctccgccgctttgaggccctggtggacggggagagccag
cgctacgccgccttcgggggcaaggagctaagggagcgcttcttcaacacccccgagctt
aagaagctcattgaggggatgacggacgaggagctcaccgagctcacccggtcccggggc
ggccacgacatggtcaagatctacgccgcctacaaggccgcggtggagcacaggggaagc
cccgtggtcatcctcgcccggaccatcaagggctacgggatgggccccacggtcatggcc
aagaacgtggcccaccaggtgaagaagctcaccgaggaggacctgaaggaggcgaggcgc
ttcctcggcatccccattcccgaggagaagcttcccgagctcccctactaccacccgggg
ccggactcccccgaggtccgctacctcctggaacggaggaaggccctgggcggcttcgtg
cccgaaaggagggtgcgcttccaggggggcctcgaggtcccggaggaggagttcttccgg
gagttctacgagggctcaggggggcgggagatctccaccaccatggccttcgtgcgcatc
ctcgccaagctcctccgccaccccaagatcggcaagtacatcgtccccatcgtccccgac
gaggcccgcacctttggcatggaggccctgatcgcccaggtgggcgtctactccccccag
gggcagctctacgtccccgtggacgcgggcaccctcaccgcctacaaggagagccagaag
gggcagatcctggaggaggggatcaccgaggccggggccatggccgagttcatcgccgcc
gggaccgcctacgcccactggggcatccccaccatccccttcttcatcacctactccatg
ttcggcctgcaaaggatcggggacctcgtctgggccgccgccgaccagcgcgcccggggc
ttcttcctcggggccacggcggggcgcaccaccttggcgggggagggccttcagcaccag
gacggccaaagccacgtctacgccctggccgcccccaacctcctcgcctacgatcccgcc
ttcgcctacgagttcgccgtgatcctggaggacggcctccgccgcatgtacggccggggg
gaggacgtcttctactacatcaccattgagaacgagaactacgtccacccccccatgccc
gagccccgggaaaaggtcaaggaggggatcctaaaagggctttacctcttccgggcgggg
gaggggaagggcccaaaagtgcagcttttcggcaccgggcccatcctcaacgaggccctg
aaggcccaggagcttttggccaagtacggcgtggtggcggacgtctggagcgccaccagc
tacaaggccctctatgtggacgccattgaggccgagcgggagacccgccttttgggcaag
gcccgcaggccctacgtgcaggaggccctcgagggccacgaggggcccatcgtggccgcc
accgactacctcaaggccctacccaacctcatccggggatacgtggaccggcccttcgcc
gtcctcggcacggacggcttcggccgctccgacacccgggaggcccttagggacttcttt
gaggtggacgcccggcacatcgcctacaccgccctggccctgctccacggggagggcaag
gtgacgaagaggaccctgaaccaggcgaggaaggacctgggccttaagctggaggaggtg
ccgccccaccggcggtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (49)   

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