KEGG   Thermus thermophilus HB8: TTHA0345
Entry
TTHA0345          CDS       T00220                                 
Symbol
TTHA0345
Name
(GenBank) porphobilinogen deaminase
  KO
K01749  hydroxymethylbilane synthase [EC:2.5.1.61]
Organism
ttj  Thermus thermophilus HB8
Pathway
ttj00860  Porphyrin metabolism
ttj01100  Metabolic pathways
ttj01110  Biosynthesis of secondary metabolites
ttj01120  Microbial metabolism in diverse environments
ttj01240  Biosynthesis of cofactors
Module
ttj_M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:ttj00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00860 Porphyrin metabolism
    TTHA0345 (TTHA0345)
Enzymes [BR:ttj01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.61  hydroxymethylbilane synthase
     TTHA0345 (TTHA0345)
SSDB
Motif
Pfam: Porphobil_deam Porphobil_deamC
Other DBs
NCBI-ProteinID: BAD70168
UniProt: Q5SLE8
Position
1:complement(326557..327462)
AA seq 301 aa
MRVVVVGTRGSALALAQTRFVVERLKETWPETEFKIRTIKTRGDQGASPREEAIFVKEIQ
EALLSREIDIAVHSLKDLPTESPRGLKIASVPRRQDPRDVFLGKAAKRLKDLPPGAVVGT
SSVRRKAQILALRPDLVVRDLRGNVDTRLAALGNGEYDGIVLAAAGLIRLDLRNRIDEFL
DPGEVLPAPGQGALALEVREGDDLAEELCYALHHPPSYHRVRAERAFLRGLGAGCLAPVG
ALAHVEEDGTLRLEGVLLTPDGKSFIRAEIEGDVSEAEELGLDLARDVLEQGGREILAQI
R
NT seq 906 nt   +upstreamnt  +downstreamnt
atgcgcgtcgtcgtggtgggaacccgggggagcgccctggccctggcccagacccgcttc
gtggtggagaggctcaaggagacctggcccgagacggagttcaagatccgcacgattaag
acccggggggaccagggggcgagcccgagggaggaggccatcttcgtcaaggagatccag
gaggccctgctctcccgggagattgacatcgccgttcactccctcaaggacctgcccacc
gagtcgccccgggggctcaagatcgcctccgtgccccggcggcaggacccccgggacgtc
ttcctgggcaaggcggccaagcgcctcaaggacctccccccgggggcggtggtggggacg
agctccgtgcgccgcaaggcccagatcctcgccctgaggccggacctcgtggtgcgggac
ctccggggcaacgtggacacccggctcgccgctttgggcaacggggagtacgacggcatc
gtcctcgcggcggcggggctcatccgcctggacctcaggaaccgcattgacgagttcctg
gaccccggcgaggtgctccccgcccccggccagggggccttggccctggaggtgcgggaa
ggggacgacctggccgaggagctctgctacgccctgcaccaccccccctcctaccaccgg
gtccgggcggagcgggctttccttaggggccttggggccgggtgcctggcccccgtgggg
gccctcgcccacgtggaggaggacgggacgctgcggcttgagggggtcctcctcaccccg
gacgggaagagcttcatccgggcggagattgagggggatgtttccgaggccgaggaactg
gggctggacctggcccgggacgtcctggagcagggcgggcgggagatcctcgcccaaatc
cgatag

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