KEGG   Thermoanaerobacterium thermosaccharolyticum DSM 571: Tthe_1462
Entry
Tthe_1462         CDS       T01299                                 
Name
(GenBank) DNA topoisomerase I
  KO
K03168  DNA topoisomerase I [EC:5.6.2.1]
Organism
ttm  Thermoanaerobacterium thermosaccharolyticum DSM 571
Brite
KEGG Orthology (KO) [BR:ttm00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:ttm03032]
    Tthe_1462
   03400 DNA repair and recombination proteins [BR:ttm03400]
    Tthe_1462
Enzymes [BR:ttm01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.1  DNA topoisomerase
     Tthe_1462
DNA replication proteins [BR:ttm03032]
 Prokaryotic type
  DNA Topoisomerases
   Tthe_1462
DNA repair and recombination proteins [BR:ttm03400]
 Prokaryotic type
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHIIR (short-homology-independent illegitimate recombination)
     Facilitator
      Tthe_1462
SSDB
Motif
Pfam: Topoisom_bac Toprim zf-C4_Topoisom RNA_POL_M_15KD Zn_ribbon_recom Toprim_4 Auto_anti-p27 Zn_Tnp_IS1595 Lar_restr_allev zf-LSD1
Other DBs
NCBI-ProteinID: ADL68976
UniProt: D9TN66
Position
complement(1462995..1465055)
AA seq 686 aa
MEKSLVIVESPSKAKTIHKYLGKNYKVEASMGHIRDLPKSQLGIDIEKNFEPKYITIRGK
GPIIEKLKKEAKNASKIYLATDPDREGEAISWHLANLLNIDVNDKCRIEFHEITKNAIQN
AIKNPRKINMNLVDAQQARRILDRLVGYNISPLLWKKIKRGLSAGRVQSVATRLICDREK
EIEEFKPEEYWSLSAFLYKEKKTQYFEAKFYGTKDGKIDLKNENDVNNIIKDLADDYIVD
NVKTGTKKRNPSPPFITSTMQQEASKKLGFTAKKTMMIAQQLYEGVEIKGEGSLGLITYM
RTDSTRISEEAKKAAYEYILQKYGKEYANPNTTYTKKGGNIQDAHEAIRPTYINLDPDQI
KDSLKPDQYKLYKLIWSRFLASQMSQALYDTITMDIINKNYIFKASGSKLKFAGFMTVYI
EEADTENIEEKTLPLLEKGDHLKLKVLKPEQHFTQPPARYTEATLIKELEEKGIGRPSTY
APIISTLLERGYVIKEKKNLKPTELGFIVTDVMKEFFPDIVDVKFTAEMEEQLDKIEEGI
EKWCDVIDGFYNNFNDSLKVAEEQMKDIEIKDEVTDIKCEFCGRNMVIKYGRYGKFLACP
GFPECKNTKPLYEETGIICPKCGGKIIVKKSKRGKTYYACENSSQCGTMFWDKPINETCP
KCGNLLMEKYIKGNKVIKCSNCDYVK
NT seq 2061 nt   +upstreamnt  +downstreamnt
atggaaaaatcattggtaatagttgaatcaccctcaaaggctaaaacaatacataaatat
ttaggaaaaaattataaagttgaagcctcgatggggcatataagggatttgccaaaaagt
cagcttggcatagatattgagaaaaatttcgagcccaaatatataacgattcgtggcaaa
ggaccaataatagagaaattaaaaaaagaagcaaaaaatgcttcgaaaatttaccttgcg
acagaccctgatagggaaggggaagctatatcatggcatcttgctaatcttttaaatata
gatgtcaatgataaatgcagaatagagtttcatgaaataacaaaaaatgcgatacaaaat
gctattaaaaatcctcgaaagataaacatgaatttagttgatgcgcagcaagccagaaga
atacttgacaggcttgtaggctacaatattagcccattgctgtggaaaaaaataaaaaga
ggtctaagcgctggaagagttcagtcagttgccacaagattaatttgtgatagggaaaaa
gaaatagaagaatttaagcctgaagagtattggagcttatctgcttttttgtataaggaa
aagaaaacgcagtatttcgaagcaaagttttatggaacaaaagatggaaaaatagattta
aaaaatgaaaatgatgtaaataacattataaaagatttggcagatgattacatcgtagat
aatgtcaaaacaggcactaaaaagagaaatccttctcctccatttataacaagtacgatg
caacaagaagcttctaaaaagcttggatttactgcaaaaaagactatgatgattgcgcaa
caattatacgaaggagttgaaataaaaggggaaggaagtctaggcttaataacttatatg
agaacagattctacaagaatatctgaagaggctaaaaaagctgcatatgaatatatactg
caaaaatatgggaaagaatatgcaaatcctaatacaacatatacaaagaaaggaggaaat
attcaggatgctcatgaagctatacgacctacatatataaacttagatccggaccagatt
aaagattcattaaaaccagatcaatataagctatacaaattaatatggagccggttttta
gcaagccagatgtcacaagctctatatgatacgataactatggatattattaataaaaat
tatatctttaaagcaagcggctctaaactaaaatttgcgggatttatgacggtatatatt
gaggaagcagatactgaaaatattgaagaaaaaacacttccgctacttgaaaaaggagat
cacttaaaattgaaggtgttaaagcctgaacagcattttacacagcctcctgctagatat
actgaggccactttgataaaagaactagaagaaaaaggaataggaaggcccagcacgtat
gctcctataatatctacactgcttgaaagaggatatgtaataaaagaaaagaaaaactta
aagccaactgaattgggttttatcgtaacagacgtgatgaaagaattttttccagatatt
gtggatgtaaaatttactgccgaaatggaagaacaacttgataagatagaagaaggtata
gaaaaatggtgcgatgtaattgatggattttataataattttaatgattccttaaaggtt
gcagaggagcagatgaaagacattgaaataaaagatgaagttacagatataaaatgtgaa
ttttgcggtagaaatatggttataaaatatgggcgatatggcaaatttttggcttgcccg
ggatttcctgaatgcaaaaacactaaaccgctatatgaagaaacaggaataatatgccct
aaatgtggagggaaaataattgttaagaaaagtaaaagaggaaagacatactatgcttgt
gaaaattcatctcagtgtggtactatgttttgggataagccaataaatgaaacatgccct
aaatgtggaaatttacttatggaaaaatatatcaaaggaaataaggtaattaaatgtagt
aattgcgattatgtaaagtaa

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Ontology (4)   
   KEGG BRITE (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (43)   
   KEGG ORTHOLOGY (1)   
   RefGene (40)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (10)   
   Pfam (10)   
All databases (60)   

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