KEGG   Tupaia chinensis (Chinese tree shrew): 102469549
Entry
102469549         CDS       T02978                                 
Symbol
ARHGEF12
Name
(RefSeq) Rho guanine nucleotide exchange factor 12
  KO
K07532  Rho guanine nucleotide exchange factor 12
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04270  Vascular smooth muscle contraction
tup04360  Axon guidance
tup04611  Platelet activation
tup04625  C-type lectin receptor signaling pathway
tup04810  Regulation of actin cytoskeleton
tup05135  Yersinia infection
tup05152  Tuberculosis
tup05163  Human cytomegalovirus infection
tup05200  Pathways in cancer
tup05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:tup00001]
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102469549 (ARHGEF12)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102469549 (ARHGEF12)
   04625 C-type lectin receptor signaling pathway
    102469549 (ARHGEF12)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    102469549 (ARHGEF12)
  09158 Development and regeneration
   04360 Axon guidance
    102469549 (ARHGEF12)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    102469549 (ARHGEF12)
   05205 Proteoglycans in cancer
    102469549 (ARHGEF12)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    102469549 (ARHGEF12)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102469549 (ARHGEF12)
   05152 Tuberculosis
    102469549 (ARHGEF12)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tup04131]
    102469549 (ARHGEF12)
Membrane trafficking [BR:tup04131]
 Others
  Rho GTPase associated proteins
   Rho guanine nucleotide exchange factors (GEFs)
    102469549 (ARHGEF12)
SSDB
Motif
Pfam: RGS-like PH_16 RhoGEF PDZ PDZ_6 PDZ_2 PH_13 Ribonuc_2-5A Tricorn_PDZ AAA_23
Other DBs
NCBI-GeneID: 102469549
NCBI-ProteinID: XP_014443406
Position
Un
AA seq 1526 aa
MSGSQPTITDRFPLKKPIRHGSILNRESPTDKKQKVERSASHDFDPTDSSSTKTKSSSEG
SRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGT
LVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEASVTGPMSPIMTSPHSPG
ASGNMERITSPVLMGEENNVVHSQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQ
ETKKHIPQLQEQLSKATGSAQDGAVVTPGRPLSDTLPSSEAEADPGDGLGRSDCGSGDAS
RPSSDNADSPKSGLKERIYLEETLEKTDVVADPDTQSLVGSPSARTAPHIIGAEDDDFGT
EHEQINGQCSCFQSIELLKSRPAHLAVFVHHVVSQFDPATLLCYLYSDLYKQTNSKETRR
IFLEFHQFFLDRSAHLKVSVPDEISVDLEKRRPELIPEDLHRHYIHTMQERVHPEVQRHL
EDFRQKRSMGLTLAETELTKLDAERDKDRVALDKERACAEQIVAKIEEVLMTAQAVEEDR
SSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSI
LGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDFAKSRQSGLVNEGPDAGY
LPANPMSSVASGATVSQEGGKENDTGSKQVGEAPASGDSVDGPPRTPNTVFDFPAPPLEQ
VQEEDCEVERMTEHGTPKPFRKFDSLAFGESQSEDEQFENDLETDLPNWQQLVSREVLLG
LKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQ
LHIGLNEQMKAVRKRNETSVIEQIGEDLLTWFSGPGEEKLKQAAATFCSNQPFALEMIKT
RQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTDREKV
KRAADHCRQILNYVNQAVREAENKQRLEDYQRRLDTSNLKLSECPNVEELRNLDLTKRKM
IHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVI
KLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTK
PIPLPPSPPCEGDNDEEQPPKLKGDHHGISVPSLQSPDRELGLASPLLPSKPQSHSLSTS
GKAEVDDLFVTESQFAKERHADGTLKEAGVGYPFTAPEPHLPISEERWALDALRNLGLLK
QLLAQQLGVTEKHAQEDWRHFPRCRTASRGAQADSGIRNTEGIRAHHHAEGQPPFRTGTG
DSAPRYSPRTSTESSAPRDSVVLASPESQASSILVMDHMIPTPEMPAAEPEGGLDESGEH
FFDAREAHSDDNPSEGNYLILDGYEAVQESSTDEEVASSLPPQPATGTSPMDSTHQQQHS
PQNAHSDGAASPFTPEFLVQQRWGAIEDTCFEIQSPSCTDAQSQIMEYIHKIEADLEHLK
KVEESYSVLCQRLAASALTDKHSDKS
NT seq 4581 nt   +upstreamnt  +downstreamnt
atgagtggctcacagcccactatcaccgacaggtttcccctcaaaaaacctataaggcat
ggaagtattttgaaccgagagtcaccaacagataagaagcagaaagttgagcgcagtgca
tcacatgattttgaccccacagatagctcctccacgaagacaaagtctagctcagagggg
agtagatccgagatatatggtctggttcagcgttgcgtgataatccagaaagatgacaat
ggatttgggctgacggtcagtggagacaatccagtcttcgtacagtctgtcaaagaagat
ggagcagccatgcgggccggagtacagacaggtgatcggatcatcaaggtgaatggaact
ctggtgactcactcaaaccatctggaggtggtgaagctaatcaaatctggttcctatgta
gctctcactgtccagggacgcccccctgggtcgccccagatcccacttgccgattcggaa
gtagaagcgtcagtcactggacctatgtctcccatcatgacatcccctcactcacctgga
gcctccgggaacatggagagaatcaccagccctgtgctcatgggggaggaaaacaatgtg
gttcacagccagaaggtagaaattctgagaaaaatgttacagaaagaacaggagcggcta
cagttactgcaggaagattacaaccgaacacctgcccaaagattgctaaaagagattcaa
gagaccaagaagcacatccctcagctgcaagagcagttatcgaaagccaccggctcagct
caggacggagctgttgtcacacccggcaggcctttaagtgacaccctacccagcagcgag
gcagaagcagatcctggagatggcctgggcaggagtgactgcggcagtggagatgcctcg
cggcccagcagtgacaacgccgacagtcccaagagcggcctgaaagagaggatttatcta
gaggagaccttggagaaaaccgacgtggtggcggaccctgacacgcagtcactggtcggg
agcccctcagcccggacagcgcctcatatcattggagcagaggacgatgattttggcact
gagcacgagcagatcaacgggcagtgcagctgtttccagagcatcgagctgctcaagtct
cgccccgctcacctggcagtgtttgtgcaccacgtggtctcgcagttcgaccctgccacg
ctgctctgttatctctattcagacctgtataaacagaccaattccaaggagacccgccgc
atcttcctggaatttcatcagttcttcctggatcgatcagcgcacctgaaagtttctgtt
cctgacgagatatctgtggatctcgaaaagaggaggcctgagcttattcctgaggatcta
catcgccactatatccacaccatgcaagaaagagttcacccagaagttcagaggcactta
gaagattttcggcagaaacgtagcatgggactgaccctggcagagaccgagctgaccaag
ctcgatgcagagcgggacaaggaccgggtggctctggacaaggagcgggcgtgtgcagag
cagatcgtggccaaaatcgaagaggtgctgatgactgctcaggctgtagaagaagataga
agttccacgatgcagtatgttatcctcatgtacatgaagcacctgggagtcaaagtgaaa
gagcctcggaatttggagcacaagcgaggtcggattgggttccttcccaaaatcaagcaa
agtatgaagaaagacagagaaggcgaagaaaaagggaaacgaagagggttccctagcatc
ctgggccccccgaggagacccagccggcatgacaacagcgcaattggcagagccatggaa
ctgcagaaggcgcgccaccctaagcacctgtccacaccctcgtctgtgagtccggagcct
caggacttcgccaagtcacgccagagcgggttggtgaatgaaggaccagatgctgggtac
ctgcctgccaatcccatgtcctctgtggcttcaggggccacggtttcccaggaaggaggg
aaagagaacgacacagggtcaaagcaagttggagaagcaccagcttcgggagactccgta
gacggcccgcctcgcactcccaataccgtcttcgatttcccagcgcctcccttagagcaa
gtgcaggaggaggactgcgaggtggaaaggatgactgaacatgggacaccaaagcccttt
cgaaagtttgacagcttagctttcggagaaagtcaaagtgaggatgaacaatttgaaaac
gacttggagacggatctgcccaactggcagcagctcgtcagccgggaagtattgctgggc
ctaaaaccttctgagatcaaaaggcaggaagtgattaatgaactgttctacaccgaaaga
gcgcacgttcgaaccctgaaggttctcgatcaggtgttctaccagcgagtatcccgagag
ggaatcctgtcaccttcggaactacggaagatattttcaaacttggaagatattcttcaa
cttcatattgggttgaatgagcaaatgaaggctgttcggaagaggaatgagacctctgtt
attgaacagattggagaagatttactgacctggttcagtggaccaggagaggagaagctg
aagcaagctgctgctaccttttgcagtaaccaacctttcgccctggaaatgatcaagact
cgtcagaaaaaggactcccgattccagacttttgtgcaagatgccgagagtaatccactg
tgccgtcgacttcagctgaaagatatcatccccacccaaatgcagaggctcaccaagtac
ccactgctgttggataatattgccaagtacacagaatggccaacagacagggagaaggtg
aagagggccgcagatcactgtcgtcagatcttaaattatgtaaaccaagccgtcagagag
gcagaaaacaagcagcgcctcgaggactatcagcgtcgcctcgacacctccaatctgaag
ctgtcagagtgcccgaatgttgaggagctcaggaatttagatttaacaaaaaggaagatg
atccacgaagggccattggtgtggaaggtgaatagagataaatctattgatctgtacaca
ctgctgctggaagacattctggtattgctgcagaagcaggatgataggctggtgttaagg
tgccacagtaagattctggcatcgacagctgatagcaaacacacgttcagccccgtcatt
aagctgagtacagtgctggtccggcaggtggcaacagataacaaagctttattcgtcatc
tccatgtcagacaatggagcccagatttatgagctggtggcacagacggtttctgagaag
accgtctggcaggacctcatctgccgcatggccgcgtcagtgaaggagcagtccacaaag
cccatcccgttaccgccatcaccgccatgcgaaggagacaatgacgaggagcaacctccg
aaattaaaaggggaccatcacggcatttcagtccctagcctgcagagtccagacagagag
ttggggttagcctctcccttgctgccatcgaaacctcagtcgcactcgctgagcacctct
gggaaagcagaagtggacgacctcttcgtcactgagagccagtttgcgaaggagcggcat
gcagacgggaccctgaaggaagctggcgtcggttacccgttcacggccccagagccgcac
ctgcccatctcagaagaacggtgggcactggacgcactgaggaatctgggtttgctgaag
cagctgctggcccagcagctgggcgtcactgagaagcacgctcaggaagactggcggcat
ttccctcgatgcaggaccgcgtcccggggggcgcaggcagacagtgggatccggaatacg
gaaggtattagggcccaccatcacgccgaaggacaaccgccctttagaactggaactggt
gacagtgcacctcgttacagtccacggacttcaaccgaatcttctgctccacgggattcg
gtggtactggcatccccagagagccaggcaagtagcattttagtaatggaccacatgatt
ccgaccccagagatgcctgccgcagagccagaagggggtctggatgagagtggagagcac
ttttttgatgcccgtgaagcacatagtgatgataatccatcagaaggaaactacttgatc
ctcgacggctacgaggcagtgcaggagagctccacggacgaggaggtggcgtcctcactt
cccccgcagcccgcgacgggcacctccccaatggactctacccaccagcagcagcactct
ccccagaacgctcattctgatggggcagcttcgcccttcaccccagaattcttggtccag
cagcgctggggagccatagaggacacctgctttgagatccagagtccctcttgtacagat
gcacagagccagatcatggagtacattcataagatagaggctgacctcgaacacctaaag
aaggtggaggaaagttacagcgttctttgccaaaggctggctgcatcggccctcacagac
aagcactcagataaaagttag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (10)   
   Pfam (10)   
All databases (47)   

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