KEGG   Tupaia chinensis (Chinese tree shrew): 102478575
Entry
102478575         CDS       T02978                                 
Symbol
MME, Neprilysin
Name
(RefSeq) membrane metalloendopeptidase
  KO
K01389  neprilysin [EC:3.4.24.11]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup04614  Renin-angiotensin system
tup04640  Hematopoietic cell lineage
tup04974  Protein digestion and absorption
tup05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:tup00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    102478575 (MME)
  09152 Endocrine system
   04614 Renin-angiotensin system
    102478575 (MME)
  09154 Digestive system
   04974 Protein digestion and absorption
    102478575 (MME)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102478575 (MME)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:tup01002]
    102478575 (MME)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tup04147]
    102478575 (MME)
   04090 CD molecules [BR:tup04090]
    102478575 (MME)
Enzymes [BR:tup01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     102478575 (MME)
Peptidases and inhibitors [BR:tup01002]
 Metallo peptidases
  Family M13: neprilysin family
   102478575 (MME)
Exosome [BR:tup04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102478575 (MME)
CD molecules [BR:tup04090]
 Proteins
  102478575 (MME)
SSDB
Motif
Pfam: Peptidase_M13_N Peptidase_M13
Other DBs
NCBI-GeneID: 102478575
NCBI-ProteinID: XP_014443764
Position
Un
AA seq 819 aa
MGRSESQMDITDINTPKPKKKPRWTPLEISLSVLVLLLTVIAVTMIALYATYDDGICKYI
CCFKIIHLLRNSNEYFMRETETEKKEKKTSNLNRASHCIPYMSPHCPVVPGTQDHRVPSR
MYSFILSSLPSALSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILR
DELEVVLKDVLQKPGTEDIEAVQKAKTLYRSCINESAIDSRGGAPLLSLLPDIFEWPVAV
ENWEQTYGASWTAEKSIARLNAKYGKKVFINFFVGTDDKNSMNHIIHIDQPRLGLTSRDY
YQCTGIYKEACEAYVDFMISVARLIREERGLPIDEEQISLDMNNVMELEKEIANATTKPE
DRNDPVLLYNKMTLAQIQNNFSLEINGKPFSWSNFTNEIMSTVNITITDEEEVVVYAPEY
LTKLKPILIKYSARDLQNLMSWRFIMDLISSLSRTYKESRNAFRKALYGTTSETATWRRC
ANYVNGNMENAVGRLYVEEAFAGESKHVVENLIAQIREVFIQTLDDLTWMDAETKKKAEE
KALAIKERIGYPDDIISNNNKLNNEYRELDYKEDEYFENIMQNLKFIQSKQLNKLREKVD
KDEWISGAAVVNAFYSSGRNQIVFPAGILQPPFFSVGQSNSLNFGGIGMVIGHEITHGFD
DNGRNFNKDGDLVDWWTQQSAKNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIAD
NGGIGQAYRAYQNYIKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAINSIKTDV
HSPGNFRIIGTLQNSAEFSEAFHCRKNSYMNPEKKCRVW
NT seq 2460 nt   +upstreamnt  +downstreamnt
atgggcagatcagaaagtcagatggatataactgatatcaacaccccgaagccaaagaag
aaaccacgatggacccccctggagatcagtctctcggtcctcgtcctcctcctcactgtc
atagccgtgaccatgatagcactttatgccacctacgatgatggcatttgcaagtatata
tgttgttttaagattattcatttactgagaaacagtaatgagtatttcatgagagaaaca
gaaacagagaaaaaggagaaaaagaccagcaacctgaacagggcctcacactgcattccc
tacatgtccccgcactgtccagttgttccaggcacccaggatcacagagtgccttcccgc
atgtacagcttcatcctatctagtcttccctctgctctttcagccgctcgactgatccag
aacatggatgctactgctgagccctgtacagacttcttcaagtatgcctgtggaggctgg
ttgaaacgcaacgtcattcccgagaccagctcccgttacagtaactttgacattttaaga
gatgaactagaagtcgttttgaaagatgtccttcagaaacccggaactgaagacatagag
gcggtgcagaaagcgaaaacattatacaggtcttgcataaatgaatctgctattgatagt
agaggtggagcccctctcctctcactgttgccggatatattcgagtggccagtggcagta
gaaaactgggagcaaacttatggtgcttcttggacagctgagaaatcaattgcacgtcta
aatgctaaatatgggaaaaaagtctttattaattttttcgttggcactgatgataagaac
tctatgaaccatataattcacattgaccaacctcgacttggcctcacttctagagactac
tatcaatgcactggaatatataaagaggcttgtgaagcatatgtggattttatgatttct
gtggccagattgattcgcgaggagagaggattgcccatcgatgaagagcagatatcttta
gacatgaataatgttatggaattggaaaaagaaatcgctaatgctacaactaaacctgaa
gatcgaaatgatccagtgcttctttataacaaaatgacattggcccagatccaaaataac
ttttcactagagatcaatgggaagccattcagctggtcaaatttcacaaatgaaattatg
tcaactgtgaatattactattacagatgaggaagaagtggttgtttatgctccagaatat
ttaaccaaacttaagcccattcttatcaaatattctgccagagatcttcaaaatttaatg
tcctggcggttcataatggatctcataagcagcctcagccgaacctacaaggagtccaga
aatgctttccgcaaggcgctttatggcacaacatcagaaacagcaacttggagacgttgt
gcaaactatgtcaatgggaacatggaaaatgccgttggaaggctttatgtggaagaggca
tttgctggagagagtaaacacgtggttgagaatttgattgcacagatccgagaagttttt
attcagactttagatgacctcacttggatggatgctgagacgaaaaagaaagctgaagaa
aaggccttagcaattaaggaaaggatcggctatcctgatgatattatttcaaataataac
aaactaaataatgaataccgtgagttggactacaaagaagatgaatactttgagaacata
atgcaaaatttgaaattcatccagagtaaacaactgaacaagctccgggagaaggtggac
aaggatgagtggataagtggagcagcggtagtcaatgcattttactcttcaggcagaaat
cagatagtcttcccagctggcattctgcagccccccttcttcagtgtcggacagtccaac
tcattgaactttgggggcatcggcatggtcataggacacgaaatcacccatggcttcgat
gacaatggcagaaacttcaacaaggatggagacctcgttgactggtggactcaacagtct
gcaaagaactttaaagaccagtctcaatgcatggtgtaccagtacggaaacttttcctgg
gacttggcaggtggacaacatctcaatggaattaatacactaggggaaaacattgccgat
aatggaggtattggtcaagcatacagagcctatcagaattatatcaaaaagaatggggaa
gaaaaactacttcctggacttgacctaaatcacaaacaactgttcttcttgaactttgcc
caggtttggtgtggaacctacaggccagagtatgccatcaactccattaaaacagatgtg
cacagtccaggcaatttcaggattattgggaccctgcagaattctgctgagttttcggag
gcctttcactgccgcaagaactcatatatgaacccagaaaagaaatgccgggtgtggtga

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (21)   
   KEGG ORTHOLOGY (1)   
   RefGene (17)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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