KEGG   Tupaia chinensis (Chinese tree shrew): 102480265
Entry
102480265         CDS       T02978                                 
Symbol
ACACB
Name
(RefSeq) acetyl-CoA carboxylase beta
  KO
K01946  acetyl-CoA carboxylase / biotin carboxylase 2 [EC:6.4.1.2 6.3.4.14 2.1.3.15]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup00061  Fatty acid biosynthesis
tup00620  Pyruvate metabolism
tup00640  Propanoate metabolism
tup01100  Metabolic pathways
tup04152  AMPK signaling pathway
tup04910  Insulin signaling pathway
tup04920  Adipocytokine signaling pathway
tup04922  Glucagon signaling pathway
tup04931  Insulin resistance
tup04936  Alcoholic liver disease
Brite
KEGG Orthology (KO) [BR:tup00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    102480265 (ACACB)
   00640 Propanoate metabolism
    102480265 (ACACB)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    102480265 (ACACB)
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    102480265 (ACACB)
 09130 Environmental Information Processing
  09132 Signal transduction
   04152 AMPK signaling pathway
    102480265 (ACACB)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102480265 (ACACB)
   04922 Glucagon signaling pathway
    102480265 (ACACB)
   04920 Adipocytokine signaling pathway
    102480265 (ACACB)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102480265 (ACACB)
   04931 Insulin resistance
    102480265 (ACACB)
Enzymes [BR:tup01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.15  acetyl-CoA carboxytransferase
     102480265 (ACACB)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.14  biotin carboxylase
     102480265 (ACACB)
  6.4  Forming carbon-carbon bonds
   6.4.1  Ligases that form carbon-carbon bonds (only sub-subclass identified to date)
    6.4.1.2  acetyl-CoA carboxylase
     102480265 (ACACB)
SSDB
Motif
Pfam: ACC_central Carboxyl_trans CPSase_L_D2 ACCA_BT Biotin_carb_N Biotin_carb_C Biotin_lipoyl ATP-grasp Dala_Dala_lig_C ATP-grasp_3
Other DBs
NCBI-GeneID: 102480265
NCBI-ProteinID: XP_006151548
Position
Un
AA seq 2256 aa
MSPAKCKVCFPDRRIKPSMSGLHLVKRGREHKKLDLHRDFTVASPAEFVTRFGGDRVIEK
VLIANNGIAAVKCMRSIRRWAYEMFRNERAIRFVVMVTPEDLKANAEYIKMADQYVPVPG
GPNNNNYANVELIVDIAKRIPVQAVWAGWGHASENPKLPELLCKHGIAFLGPPSEAMWAL
GDKIASTIVAQTLQIPTLPWSGSGLTVEWTEDDLLQGERISVPESIYDQGCVKDVDEGLE
VAEKIGFPLMIKASEGGGGKGIRKAESAEDFPILFRQVQSEIPGSPVFLMKLAQHARHLE
VQILADQYGNAVSLFGRDCSIQRRHQKIIEEAPATIAMPAVFEFMEQCAVRLAKTVGYVS
AGTVEYLYSQDGSFHFLELNPRLQVEHPCTEMIADVNLPAAQLQIAMGVPLHRLKDIRLL
YGESPWGLVPISFETPSNTPLARGHVIAARITSENPDEGFKPSSGTVQELNFRSSKNVWG
YFSVAAAGGLHEFADSQFGHCFSWGENREEAISNMVVALKELSIRGDFRTTVEYLINLLE
TENFQSNDIDTGWLDHLIAEKVQAEKPDIMLGVVCGALNVADAMFRTCMTDFLHSLERGQ
VLPAASLLNIVDVELIYGGVKYILKVARQSLTMFVLIMNGCHIEIDAHRLNDGGLLLSYN
GNSYTTYMKEEVDSYRITIGNKTCVFEKENDPTVLRSPSAGKLMQYTVEDGGHVEAGSSY
AEIEVMKMIMTLNVQESGQVKYIKRPGAVLEAGCVVARLELDDPSKVHPAKPFTGELPSQ
QTLPILGEKLHQVFHNVLENLTNVMSGYCLPEPFFSMKLKEWVQKLLMTLRHPSLPLLEL
QEIMTSVSGRIPAPVEKSVRRVMAQYASNITSVLCQFPSQQIATILDCHAATLQRKTDRE
VFFMNTQSIVQLVQRYRSGTRGYMKAVVLELLRRYLHVEHYFQQAHYDKCVINLREQFKP
DMSQVLDCIFSHAQVAKKNQLVIMLIDELCGPDPSLSEELTSILNELTQLSKSEHCKVAL
RARQVLIASHLPSYELRHNQVESIFLSAIDMYGHQFCPENLKKLILSETTIFDVLPTFFY
HANKVVCMASLEVYVRRGYIAYELNSLQHRELPDGTCVVEFQFMLPSSHPNRMAMPISVT
NPDLLRHSTELFMDSGFSPLCQRMGAMVAFRKFEDFTRNFDEVISCFANVPKDTPLFSKA
RNSLYSEDDYKSLREEPIHILNVAIQCSDQLEDEELVPIFRTFVQSKKNILVEYGLRRIT
FLIAQEKEFPKFFTFRARDEFAEDRIYRHLEPALAFQLELSRMRNFDLTAVPCANHKMHL
YLGAAKVKEGAEVTDHRFFIRAIIRHSDLVTKEASFEYLQNEGERLLLEAMDELEVAFNN
TSVRTDCNHIFLNFVPTVIMDPLKIEESVRSMVMRYGSRLWKLRVLQAEVKINIRQTTTG
SAIPIRLFITNESGYYLDISLYKEVTDPRSGNIMFHSFGNKQGPQHGMLINTPYVTKDLL
QAKRFQAQSLGTTYVYDFPEMFRQALFKLWGSPDKYPKDILTYTELVLDSQGQLVEMNRL
PGGNEVGMVAFKMRFKTQEYPEGRDVIVISNDITFRIGSFGPGEDLLYLRASEMARAEGI
PKIYLAANSGARIGLAEEIKHMFHVAWVDPEDPLKGFKYLYLTPQDYTRISSLNSVHCEH
IEEGGESRYVITDIIGKDDGLGVENLRGSGTIAGESSLAYEEIVTISMVTCRALGIGAYL
VRLGQRVIQVENSHIILTGASALNKVLGREVYTSNNQLGGVQIMHYNGVSHITVPDDFEG
VYTILEWLSYMPKDNRSPVPIITPADPIDREIEFLPSRAPYDPRWMLAGRPHPVLKGTWQ
SGFFDQGSFKEIMAPWAQTVVTGRARLGGIPVGVIAVETRTMEVAVPADPANLDSEAKII
QQAGQVWFPDSAYKTAQAIRDFNREKLPLIIFANWRGFSGGMKDMYDQVLKFGAYIVDGL
RQYKQPILIYIPPYAELRGGSWVVVDSTINPLYMEMYADKESRGGVLEPEGTVEIKFRKK
ELVKAMRRTDSAYKKLMEQLGGAQLTDKDRKDLESRVKAREDLLLPIYHQVAVQFADLHD
TPGRMLEKGVICDVLEWKTARTFLYWRLRRLLLEDQVKQEILRACGELSHVHVQSMLRRW
FVETEGAVKGYLWDNNQVVVQWLEQHWQTGEGLRSTIHENIKYLKRDSVLKTIRGLVQEN
PEVAVDCVVYLSQHISPSERAQVIHLLSTMETPAST
NT seq 6771 nt   +upstreamnt  +downstreamnt
atgagtcctgccaagtgcaaggtctgtttccctgatcgcagaataaaaccaagcatgtcg
ggactccacctggtgaagcggggacgcgaacacaagaagctggacctgcacagagacttt
actgtggcctcccctgccgagtttgtcactcgctttgggggggaccgggtcattgaaaag
gtgcttatcgccaacaacggcatcgctgccgtgaagtgcatgcgctctatccgcaggtgg
gcctatgaaatgttccgcaatgagcgggccatccgcttcgtagtcatggtgactcccgag
gacctcaaggccaatgcagagtacatcaagatggcagatcagtatgtccctgtccctgga
gggcctaataacaacaactatgccaacgtggagctgattgtggacattgccaagaggatc
cctgtgcaggcggtgtgggctggctggggccatgcttctgaaaaccccaaacttccggaa
ctgctgtgcaagcatggaattgctttcttaggccctcccagtgaggccatgtgggccctc
ggagataagatcgcctccaccatcgtggcccagaccctgcagattccaaccctgccctgg
agtggaagcggtctgacagtggagtggacggaagatgacctgctgcagggggaaaggatc
agcgtcccagaaagcatttacgaccagggttgtgtgaaagacgtggatgagggattggag
gtggcagaaaaaatcggttttccattgatgatcaaagcttctgagggcggcggagggaaa
ggaatcaggaaggccgagagtgccgaggacttccccatccttttcagacaagtgcagagc
gagatcccaggttcgcctgtttttctcatgaagttggcccaacacgctcgccacctggaa
gtccagatcctcgccgaccagtatgggaatgcggtgtctctgtttgggcgagactgctcc
atccagaggcgacaccagaagatcattgaggaggcaccagccacaattgccatgccggct
gtgttcgagttcatggagcagtgtgcagtccgcctggccaagactgtgggctacgtaagc
gcagggacagttgagtacctctacagccaggatggcagcttccacttcttggagctgaat
cctcgcttgcaggtggaacatccctgcacagaaatgatcgctgacgtcaacctgccggct
gcccagctacagattgccatgggcgtgccactgcaccggctgaaggatatccggcttctg
tacggagagtcgccctggggactggtgcccatttcttttgaaaccccttcgaacactccc
ctggcccgaggccacgtcatcgcagcaagaatcaccagtgaaaatccagatgaggggttt
aagccgagctccggtactgtccaggaactgaatttccgtagcagcaagaacgtgtggggt
tacttcagcgtggctgctgccgggggcttacatgagttcgccgattcccagtttggacac
tgcttctcctggggagaaaaccgggaagaggccatctcgaacatggtggtagctttgaag
gagctgtccatccggggtgacttccggactactgtggagtacctcattaacctcctggag
actgagaacttccagagcaacgacatcgacacggggtggctggaccacctcatcgctgag
aaagtgcaggctgagaagccggacatcatgcttggggtggtgtgtggggccttgaacgtg
gccgacgcgatgttcagaacctgcatgacggatttcttacactccctggaaaggggccag
gtcctcccggcagcttctctgctgaacattgtggacgtggagttgatttatggaggtgtc
aagtacattctcaaggtggcccggcagtctctgaccatgttcgttctcatcatgaacggc
tgtcacatcgagatcgatgctcaccggctgaacgacggcgggttgctgctgtcctacaat
ggcaacagctacaccacctacatgaaggaagaggtcgacagttaccgaattaccattggc
aacaagacgtgtgtgttcgagaaggagaatgatcccacggtcctgaggtccccctcggcg
gggaagctgatgcagtacacggtggaggatgggggccatgtcgaggccgggagcagctat
gctgagatagaggtgatgaagatgatcatgaccttgaatgtgcaggagagcggccaggtg
aagtacatcaagcggccaggggctgtgctggaagcaggctgtgtggtggccaggctggag
ctggatgatccctcgaaagtgcacccggccaagccgttcacaggagagcttccttcccag
caaactcttcccatcctcggagagaagctgcaccaggttttccacaatgtcttggaaaac
ctgaccaacgtcatgagtggctactgtctgccagagccttttttcagcatgaagctgaag
gagtgggtgcagaagctcctgatgaccctccggcacccgtcgctacctctgctagagctg
caggagatcatgaccagcgtgtcaggacgcatccccgccccggtggagaagtcggtccgc
agggtgatggcccagtatgccagcaacatcacctccgtgctgtgccagtttcccagccag
cagattgccaccatcctggactgccatgcagccaccctgcagcggaagaccgaccgagag
gtcttcttcatgaacacccagagcatcgtgcagttggtccagagataccggagtgggacc
cgtggctacatgaaagcggtggtgttggagctcctgcgaagatatttgcacgtcgagcac
tatttccaacaagcccactacgacaagtgtgtgataaacctgcgggagcagtttaagcca
gacatgtcccaggtgctcgactgcatcttttcccacgcgcaagtggctaagaaaaaccag
ctggtgatcatgttgattgatgagctctgtggcccagacccctccctgtcggaagagctc
acctccatcctcaatgaactcactcagctgagcaaaagcgagcactgcaaagtggccctc
cgcgcccgacaggtcctgattgcctcccaccttccatcctatgaactcagacacaaccag
gtggaatcgattttcctctctgccattgacatgtatggccatcagttctgcccagaaaac
ctcaagaaattaatactctcagaaacaaccatatttgacgtcctacccactttcttctat
cacgcaaacaaagtcgtgtgcatggcttccttggaggtgtacgtacggaggggctacatt
gcctatgagctaaacagcttgcagcaccgggagctcccagacggcacctgcgtggtagaa
ttccagttcatgctgccctcttcccacccaaacaggatggccatgcccatcagcgtcacc
aaccctgatctgctaaggcacagcacagaactcttcatggacagtggcttctctccactg
tgccagcggatgggcgccatggtggccttcagaaaattcgaggatttcaccaggaacttc
gatgaagtcatctcctgcttcgccaatgtgcccaaggacacccccctcttcagcaaggcc
cgcaactccctgtactctgaggatgattacaagagcctcagagaagaacccattcacatc
ttgaatgtggccatccagtgctcagaccaactggaggacgaggagctggtgcccatcttc
cggacgttcgtgcaatccaagaaaaatatccttgtggaatatggactccgaagaatcacg
ttcttgatcgcccaagagaaagaatttcccaagtttttcacattcagagcaagagatgag
tttgcagaagatcgcatctaccgtcacctggagcccgccctggccttccagctggagctc
agccggatgcgcaactttgacctgactgccgtgccctgtgccaaccacaagatgcacttg
tacttgggcgctgccaaggtgaaggaaggggcagaagtgacagaccacaggttcttcatc
cgcgccattatcaggcactcggacctggtcacaaaggaagcttccttcgagtacctgcag
aatgagggcgagcggctgcttctggaggccatggatgagctggaggtggcgttcaacaac
accagtgtgcgcaccgactgcaaccacatcttcctcaacttcgtgcctaccgtcatcatg
gaccctctcaagatcgaggagtccgtgcgctccatggttatgcgctacggcagccggttg
tggaaactccgcgtgctacaagctgaggtcaagatcaacatccgccagaccaccactggc
agtgccattcccatccgcctgttcatcaccaacgagtcgggctactacctggacatcagc
ctctacaaagaagtgactgaccccagatccggaaacatcatgtttcactccttcggcaac
aaacaagggccccagcatgggatgctgatcaacactccctacgtcaccaaggacctgctt
caggccaagagattccaggctcagtccttggggaccacctacgtgtacgacttcccggaa
atgttcaggcaggccctctttaaactgtggggttccccagacaagtaccccaaagacatc
ctgacgtacacggagctagtgttggactcccagggccagctggtggagatgaaccgactt
cctggtgggaacgaggtgggaatggtagccttcaaaatgagatttaagactcaggagtat
ccagaaggacgggacgtgattgtcatcagcaacgatatcaccttccgcattggctccttt
ggaccaggggaggaccttctgtacctgcgtgcctctgagatggcccgggcagagggcatc
cccaaaatctacctggcagccaacagtggggcccgcattggcctggctgaggagatcaaa
cacatgttccacgtggcttgggtagacccagaagatcccctcaaaggatttaagtacctg
tacctgactcctcaagactacaccagaatcagttccctgaactctgtccactgtgagcac
atcgaggaaggaggagagtccagatacgtcatcacagacatcattgggaaggatgatggc
ctgggcgtggagaacctgaggggctcaggcacaattgctggggagtcctccctggcttac
gaagaaatcgtcaccattagcatggtgacctgccgagcccttggaatcggggcctactta
gtgaggctgggccaacgagtgatccaggtggaaaactcccacatcatcctcaccggagcc
agtgccctcaacaaggtcttgggaagagaggtttacacctccaacaaccagctaggtggc
gtgcagatcatgcattacaacggtgtctcccacatcactgtgccggacgacttcgagggg
gtttacaccatcctggagtggctgtcctacatgcccaaggataatcgcagtccagtccct
atcatcacacccgctgaccctattgacagagaaattgaattccttccatccagagcaccc
tatgatcctcggtggatgcttgcaggaaggcctcacccagtgctgaagggaacctggcag
agtggcttcttcgaccagggaagtttcaaggaaatcatggcaccctgggcccagaccgta
gtgacgggacgagccaggctgggcggcatccctgtcggagtgattgctgtggagacacgg
accatggaggtggcagtccctgcagacccggccaatttggactctgaggccaagattatc
cagcaggccggccaggtgtggttcccagactcggcctacaagacggcccaggccatcagg
gatttcaaccgggagaagctgccgctgattatctttgccaactggaggggcttctctggt
ggcatgaaagacatgtacgaccaggtgctgaagtttggcgcctacatcgtggacggcctc
aggcagtacaaacagcccatcctcatctacatcccgccctacgcggagctccggggcggc
tcctgggtggtggtcgactctaccatcaaccccctatacatggaaatgtatgcagacaaa
gagagcagagggggtgtcctggagccggaggggacagtggagattaagttccgaaagaaa
gaactggtaaaggccatgcggaggaccgactcagcatacaagaagctcatggaacagcta
ggaggggcccagctcaccgataaggacaggaaggacctggagagccgggtgaaggcccgt
gaagacctgttactccccatctaccaccaggtggcagtgcagttcgccgacctccacgac
acacctggcaggatgctggagaagggcgtcatctgtgacgtcctggagtggaagacagct
cgcactttcctgtactggcgcctgcgccgcctcctcctggaggaccaggtcaagcaggag
atcctgcgggcttgtggggagctcagccacgtgcacgtccagtccatgctgcggcgctgg
ttcgtggaaacggaaggagccgtcaagggctacctgtgggacaacaaccaggtggtggtg
cagtggctggagcagcactggcagacgggggagggcctgcgctccaccatccacgagaac
atcaagtacctgaagcgcgactccgtcctcaagaccatccggggcctggttcaggaaaac
cccgaggtggctgtggactgcgtggtgtacttgagccagcacatcagcccatccgagcgg
gcccaggtcattcacctgctatccaccatggagaccccggcctccacttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (4)   
   KEGG ENZYME (3)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (10)   
   Pfam (10)   
All databases (64)   

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