KEGG T02978: 102488414

Tupaia chinensis (Chinese tree shrew): 102488414

Entry

102488414         CDS       T02978

Symbol

PKLR

Name

(RefSeq) pyruvate kinase, liver and RBC

K12406

pyruvate kinase isozymes R/L [EC:2.7.1.40]

Organism

tup Tupaia chinensis (Chinese tree shrew)

Pathway

tup00010

Glycolysis / Gluconeogenesis

tup00620

Pyruvate metabolism

tup01100

Metabolic pathways

tup01200

Carbon metabolism

tup01230

Biosynthesis of amino acids

tup04910

Insulin signaling pathway

tup04930

Type II diabetes mellitus

tup04932

Non-alcoholic fatty liver disease

tup04950

Maturity onset diabetes of the young

Module

tup_M00001

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate

tup_M00002

Glycolysis, core module involving three-carbon compounds

Brite

KEGG Orthology (KO) [BR:tup00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    102488414 (PKLR)
   00620 Pyruvate metabolism
    102488414 (PKLR)
09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    102488414 (PKLR)
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    102488414 (PKLR)
   04950 Maturity onset diabetes of the young
    102488414 (PKLR)
   04932 Non-alcoholic fatty liver disease
    102488414 (PKLR)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tup04147]
    102488414 (PKLR)
Enzymes [BR:tup01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     102488414 (PKLR)
Exosome [BR:tup04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   102488414 (PKLR)

SSDB

Motif

Pfam:

PK PK_C HpcH_HpaI IMPDH

Other DBs

NCBI-GeneID:

102488414

NCBI-ProteinID:

XP_006153503

Position

AA seq 543 aa
MEGPAGYLRRASVAQLTQELGTAFFQRQQLPAAMADTFLEHLCLLDIDSEPVAARSTSII
ATIGPASRSVERLKDMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFSSSPLGYRPV
AIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGTKNTVWVDYPNIVRVV
SVGGHIYIDDGLISLEVQKIVPEGLVTKVESGGVLGSRKGVNLPGAQVDLPSLSEQDMKD
LRFGVEHGVDIVFASFVRKASDVVAVRAALGPEGQGIKIISKIENHEGVKKFDEILEVSD
GIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMTTKPRPTRAETSDV
ANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDP
TEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRG
VFPLLYREPPVAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVL
SIS

NT seq 1632 nt +upstreamnt +downstreamnt
atggaagggccggcggggtacctgcggcgggccagcgtggcccagctgacccaggagctg
ggcactgccttcttccagcggcagcagctgccggctgctatggcggacaccttcctggaa
cacctgtgcctgctggacatcgactctgagcccgtggccgctcgcagcaccagcatcatc
gccaccatcgggccagcatctcgctccgtggagcgcctcaaggacatgatcaaggctggg
atgaacatcgcccgcctcaacttctcccacggctcccatgagtaccacgccgagtccatc
gccaacgtccgggaggcggtggagagcttttcgagttccccgctcggctaccggccggtg
gccatcgcgctggacaccaagggcccggagattcgcaccgggatcctgcaagggggcccg
gagtcggaagtggagctcgtgaagggttcccaggtgctggtgactgtggacccggcgttt
cggacccgggggaccaagaacacggtgtgggtggactaccccaatatcgtccgggtcgtg
tcggtcgggggccacatctacattgacgacgggctcatctccctagaggtccagaaaatc
gtcccagagggcctggtgaccaaagtggagagcggcggtgtcctaggcagccgaaagggc
gtcaacttgccgggcgcccaggtggacctgcccagtctgtctgagcaagatatgaaggac
ctgcgcttcggggtggagcacggtgtggacattgtctttgcctcttttgtgcggaaagcc
agcgacgtggttgccgtccgggctgctctggggccggaagggcagggcattaagatcatc
agcaaaatcgaaaaccacgaaggcgtgaagaagtttgatgaaatcctggaagtgagcgat
ggcatcatggtggcccggggggacctgggcatcgagatcccagcggagaaggttttcctg
gctcagaagatgatgattggccgctgcaacttggctggcaagccggtcgtctgtgccaca
cagatgctggagagcatgaccaccaagccccggcctacacgggcggagacgagtgacgtg
gccaatgccgtgctggacggagccgactgcatcatgctgtccggggagactgccaagggc
aacttccccgtggaggccgtgaagatgcagcatgcgattgcccgggaggccgaggctgca
gtgtaccaccggcagctgtttgaagagctacgccgggcagcacccctgagccgtgacccc
actgaagtcaccgccattggggccgtggaggctgccttcaagtgctgtgccgctgctatc
atcgtgctgaccacgactggccgctcggcccagcttctgtctcggtaccggccccgggca
gctgtcatcgcagtcactcgctctgcccaggctgcccgccaggtccacctctgccgagga
gtcttccccttgctgtaccgcgagcctccagtggccgtctgggcagacgacgtggaccgc
cgggttcagtttggcattgaaagcggaaagctccgtggcttcctccgtgttggggaccta
gtgattgtggtgacaggctggcgccctggctctggctataccaacatcatgcgggtgctg
agcatatcctga

DBGET integrated database retrieval system