KEGG   Tupaia chinensis (Chinese tree shrew): 102491807
Entry
102491807         CDS       T02978                                 
Symbol
SRC
Name
(RefSeq) SRC proto-oncogene, non-receptor tyrosine kinase
  KO
K05704  tyrosine-protein kinase Src [EC:2.7.10.2]
Organism
tup  Tupaia chinensis (Chinese tree shrew)
Pathway
tup01521  EGFR tyrosine kinase inhibitor resistance
tup01522  Endocrine resistance
tup04012  ErbB signaling pathway
tup04015  Rap1 signaling pathway
tup04062  Chemokine signaling pathway
tup04137  Mitophagy - animal
tup04144  Endocytosis
tup04360  Axon guidance
tup04370  VEGF signaling pathway
tup04510  Focal adhesion
tup04520  Adherens junction
tup04530  Tight junction
tup04540  Gap junction
tup04611  Platelet activation
tup04613  Neutrophil extracellular trap formation
tup04625  C-type lectin receptor signaling pathway
tup04727  GABAergic synapse
tup04750  Inflammatory mediator regulation of TRP channels
tup04810  Regulation of actin cytoskeleton
tup04912  GnRH signaling pathway
tup04915  Estrogen signaling pathway
tup04917  Prolactin signaling pathway
tup04919  Thyroid hormone signaling pathway
tup04921  Oxytocin signaling pathway
tup04926  Relaxin signaling pathway
tup05100  Bacterial invasion of epithelial cells
tup05135  Yersinia infection
tup05152  Tuberculosis
tup05161  Hepatitis B
tup05163  Human cytomegalovirus infection
tup05167  Kaposi sarcoma-associated herpesvirus infection
tup05168  Herpes simplex virus 1 infection
tup05203  Viral carcinogenesis
tup05205  Proteoglycans in cancer
tup05207  Chemical carcinogenesis - receptor activation
tup05208  Chemical carcinogenesis - reactive oxygen species
tup05219  Bladder cancer
tup05417  Lipid and atherosclerosis
tup05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tup00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    102491807 (SRC)
   04015 Rap1 signaling pathway
    102491807 (SRC)
   04370 VEGF signaling pathway
    102491807 (SRC)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    102491807 (SRC)
   04137 Mitophagy - animal
    102491807 (SRC)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    102491807 (SRC)
   04520 Adherens junction
    102491807 (SRC)
   04530 Tight junction
    102491807 (SRC)
   04540 Gap junction
    102491807 (SRC)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    102491807 (SRC)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    102491807 (SRC)
   04613 Neutrophil extracellular trap formation
    102491807 (SRC)
   04625 C-type lectin receptor signaling pathway
    102491807 (SRC)
   04062 Chemokine signaling pathway
    102491807 (SRC)
  09152 Endocrine system
   04912 GnRH signaling pathway
    102491807 (SRC)
   04915 Estrogen signaling pathway
    102491807 (SRC)
   04917 Prolactin signaling pathway
    102491807 (SRC)
   04921 Oxytocin signaling pathway
    102491807 (SRC)
   04926 Relaxin signaling pathway
    102491807 (SRC)
   04919 Thyroid hormone signaling pathway
    102491807 (SRC)
  09156 Nervous system
   04727 GABAergic synapse
    102491807 (SRC)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    102491807 (SRC)
  09158 Development and regeneration
   04360 Axon guidance
    102491807 (SRC)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    102491807 (SRC)
   05207 Chemical carcinogenesis - receptor activation
    102491807 (SRC)
   05208 Chemical carcinogenesis - reactive oxygen species
    102491807 (SRC)
   05203 Viral carcinogenesis
    102491807 (SRC)
  09162 Cancer: specific types
   05219 Bladder cancer
    102491807 (SRC)
  09172 Infectious disease: viral
   05161 Hepatitis B
    102491807 (SRC)
   05168 Herpes simplex virus 1 infection
    102491807 (SRC)
   05163 Human cytomegalovirus infection
    102491807 (SRC)
   05167 Kaposi sarcoma-associated herpesvirus infection
    102491807 (SRC)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    102491807 (SRC)
   05152 Tuberculosis
    102491807 (SRC)
   05100 Bacterial invasion of epithelial cells
    102491807 (SRC)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102491807 (SRC)
   05418 Fluid shear stress and atherosclerosis
    102491807 (SRC)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    102491807 (SRC)
   01522 Endocrine resistance
    102491807 (SRC)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tup01001]
    102491807 (SRC)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:tup04131]
    102491807 (SRC)
Enzymes [BR:tup01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     102491807 (SRC)
Protein kinases [BR:tup01001]
 Non-receptor tyrosine kinases
  SRC family
   102491807 (SRC)
Membrane trafficking [BR:tup04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Kinases and associated proteins
    102491807 (SRC)
 Endocytosis
  Clathrin-mediated endocytosis
   Kinases
    102491807 (SRC)
  Lipid raft mediated endocytosis
   Caveolin-mediated endocytosis
    102491807 (SRC)
  Macropinocytosis
   Kinases
    102491807 (SRC)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_9 SH3_2 ABC1 Haspin_kinase
Other DBs
NCBI-GeneID: 102491807
NCBI-ProteinID: XP_014441637
Position
Un
AA seq 553 aa
MGSNKSKPRDASQRRRSLEPADSAHGVPGGAFPTSQTPSKPASAGGHRGPNAPFGPAATE
PKLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTRKV
DVSQTWFTFRWLQREGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESER
LLLNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQF
NSLQQLVAYYSKHADGLCHRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGE
VWMGTWNGTTRVAIKTLKPGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEY
MSKGSLLDFLKGETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVC
KVADFGLARLIEDNEYTARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGR
VPYPGMVNREVLDQVERGYRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYF
TSTEPQYQPGENL
NT seq 1662 nt   +upstreamnt  +downstreamnt
atgggcagcaacaagagcaagcccagggacgccagccagcggcgccgcagcctggagccc
gccgacagcgcccacggcgtcccgggcggggccttccccacctcgcagacccccagcaag
ccagcctctgccggtggccaccgcggccccaacgcacccttcggccccgcagccacggag
cccaagctgtttggaggcttcaactcctcggacactgtcacctccccgcagagggccggg
ccgctggctggcggagtgaccactttcgtggccctctatgactatgaatcacggacggag
accgacctgtccttcaagaaaggggagcggctccagattgtcaacaacacgaggaaggtg
gatgtcagccagacctggttcacattccgatggctgcaaagagagggagactggtggctg
gcccactcgctcagcaccggacagacgggctacatccccagcaactatgtggcgccctcc
gactccatccaggccgaggagtggtacttcggcaagatcaccagacgggagtcagagcgg
ttactgctcaacgcagagaacccgagagggaccttcctagtaagagaaagcgagaccacg
aaaggcgcctactgcctctcggtgtcggactttgacaacgccaagggcctcaacgtgaag
cactacaagatccgcaagctggacagcggcggcttctacatcacctcgcgcacccagttc
aacagcctgcagcagctcgtggcctactactccaagcatgctgacggcctgtgccaccgc
ctgaccactgtgtgccccacgtccaagccgcagacgcagggcctggccaaggacgcctgg
gagatcccgcgggagtcgctgcggcttgaggtcaagctaggccagggctgcttcggagag
gtgtggatggggacctggaacggcaccactagggtggccatcaaaaccctgaagccaggc
acgatgtctccagaggccttcctgcaggaggcccaggtcatgaagaaactgaggcacgag
aagctggtgcagctgtacgcggtggtgtccgaggagcccatctacatcgtcacggagtac
atgagcaaggggagtttgctggactttctcaagggggaaacgggcaagtacctgcggctg
cctcagctggtggacatggctgcccagattgcctccggcatggcatacgtggagcggatg
aactacgtccaccgggacctccgcgcggccaacatcctggtcggggagaacctcgtgtgc
aaggtggctgatttcgggctggctcggctcatcgaggacaacgagtacacagcccggcaa
ggtgccaaattccccatcaagtggacagctccggaagccgccctgtacggccggttcacc
atcaagtcagacgtgtggtccttcgggatcctgctgacagagctcaccacgaaggggcgg
gtgccttaccctgggatggtaaaccgcgaggtgctggaccaggtggagcggggctaccgg
atgccctgcccacccgagtgccccgagtctctgcacgacctcatgtgccagtgctggcgg
aaggagccggaggagcggcccaccttcgagtacctacaggccttcctggaggactacttc
acatccaccgagccccagtaccagcccggggagaacctatag

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (39)   
   KEGG PATHWAY (39)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (12)   
   RefSeq(nuc) (8)   
   GenBank (2)   
   EMBL (2)   
Protein domain (8)   
   Pfam (8)   
All databases (83)   

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