KEGG   Thermoanaerobacter wiegelii: Thewi_2026
Entry
Thewi_2026        CDS       T01607                                 
Name
(GenBank) glycine hydroxymethyltransferase
  KO
K00600  glycine hydroxymethyltransferase [EC:2.1.2.1]
Organism
twi  Thermoanaerobacter wiegelii
Pathway
twi00260  Glycine, serine and threonine metabolism
twi00460  Cyanoamino acid metabolism
twi00630  Glyoxylate and dicarboxylate metabolism
twi00670  One carbon pool by folate
twi00680  Methane metabolism
twi01100  Metabolic pathways
twi01110  Biosynthesis of secondary metabolites
twi01120  Microbial metabolism in diverse environments
twi01200  Carbon metabolism
twi01230  Biosynthesis of amino acids
twi01240  Biosynthesis of cofactors
Module
twi_M00140  C1-unit interconversion, prokaryotes
Brite
KEGG Orthology (KO) [BR:twi00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    Thewi_2026
  09102 Energy metabolism
   00680 Methane metabolism
    Thewi_2026
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    Thewi_2026
  09106 Metabolism of other amino acids
   00460 Cyanoamino acid metabolism
    Thewi_2026
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Thewi_2026
Enzymes [BR:twi01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.1  glycine hydroxymethyltransferase
     Thewi_2026
SSDB
Motif
Pfam: SHMT Aminotran_1_2 Beta_elim_lyase Cys_Met_Meta_PP Aminotran_5 DegT_DnrJ_EryC1 OKR_DC_1 Met_gamma_lyase NIR_SIR
Other DBs
NCBI-ProteinID: AEM79393
UniProt: G2MTD7
Position
2051286..2052536
AA seq 416 aa
MDIEIIRKTDPEIADAIEKELIRQRNKIELIASENFVSRAVMEAMGSPLTNKYAEGYPNK
RYYGGCEYVDIAEELARERLKKLFGAEHANVQPHSGAQANMAAYFALIKPGDTVLGMDLA
HGGHLTHGSKVNFSGQIYNFIYYGVREDTGYIDYDEVERVAKKHKPKLIVAGASAYPRII
DFKRFREIADKVGAYLMVDMAHIAGLVAAGLHPNPVPYADVVTTTTHKTLRGPRGGAILC
KKEYAKAIDKALFPGTQGGPLMHIIAAKAVCFKEALSDEFKEYQKRIVENAKALANALME
RGINLVSGGTDNHLMLLDLRNTGITGKELETRLDEVNITCNKNAIPFDPLGPNVTSGVRL
GTPAVTTRGMKPEDMVEIADIIVNVIRDENYKEKAKERVANLLKKYPLYEDLIQRR
NT seq 1251 nt   +upstreamnt  +downstreamnt
atggatattgaaataataagaaaaactgatccagaaattgcagacgcaattgaaaaagag
cttataaggcagagaaataaaatagagcttatagcttctgaaaattttgtaagtagagct
gtaatggaagcgatggggtcccctcttactaataaatacgcagaagggtatccaaataaa
aggtattacggcggttgcgaatatgtggatatagctgaagagttagcaagagaaaggctc
aaaaaactttttggtgctgaacacgcaaatgtacaacctcattcaggagcacaggcaaac
atggctgcttattttgctcttataaagccaggagatactgtgctgggaatggatttagcc
catggagggcacctcactcatggaagtaaagtcaatttttcaggccaaatctataatttt
atatattacggagtaagagaagatacaggatatatagattacgatgaagtagaaagagtc
gcaaaaaagcacaaacccaaattgattgtcgcaggtgctagcgcttatccaaggataatc
gattttaagagatttagagaaattgcagacaaggttggagcttacctaatggtagacatg
gctcacatagcaggtcttgtagcagcaggtcttcaccccaatcctgttccttatgctgat
gttgtcacaactaccacccataagactttaagaggtccaagaggaggggctattctttgc
aaaaaagaatacgcaaaagcaatagacaaagcactcttcccgggcacacaaggtggccct
ttaatgcacataatagcggcaaaagccgtttgttttaaagaagctctttccgatgaattt
aaagaatatcaaaaaagaattgtagaaaatgcaaaagccttagcaaatgctttaatggaa
agaggaataaacttagtgtcaggtggaactgataaccacttgatgttgttggatttaaga
aacacaggaataacaggcaaagagttagaaacaagattagatgaagtaaacataacttgc
aacaaaaatgctataccctttgacccattagggccaaatgtcacttccggtgtgagactg
ggaactccagctgtcacaacaagaggaatgaaacctgaagatatggtagaaatagcggac
attatagtcaatgtaataagggatgaaaactataaagaaaaagcaaaagagagagtagca
aatcttctcaaaaaataccctctttatgaggacctcatacaaagaagatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (15)   
   KEGG PATHWAY (11)   
   KEGG MODULE (4)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (9)   
   Pfam (9)   
All databases (41)   

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