KEGG   Ursus arctos horribilis (North American brown bear): 113241915
Entry
113241915         CDS       T05909                                 
Symbol
PLA2G4F
Name
(RefSeq) cytosolic phospholipase A2 zeta
  KO
K16342  cytosolic phospholipase A2 [EC:3.1.1.4]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah00564  Glycerophospholipid metabolism
uah00565  Ether lipid metabolism
uah00590  Arachidonic acid metabolism
uah00591  Linoleic acid metabolism
uah00592  alpha-Linolenic acid metabolism
uah01100  Metabolic pathways
uah04010  MAPK signaling pathway
uah04014  Ras signaling pathway
uah04072  Phospholipase D signaling pathway
uah04217  Necroptosis
uah04270  Vascular smooth muscle contraction
uah04370  VEGF signaling pathway
uah04611  Platelet activation
uah04664  Fc epsilon RI signaling pathway
uah04666  Fc gamma R-mediated phagocytosis
uah04724  Glutamatergic synapse
uah04726  Serotonergic synapse
uah04730  Long-term depression
uah04750  Inflammatory mediator regulation of TRP channels
uah04912  GnRH signaling pathway
uah04913  Ovarian steroidogenesis
uah04921  Oxytocin signaling pathway
uah05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09103 Lipid metabolism
   00564 Glycerophospholipid metabolism
    113241915 (PLA2G4F)
   00565 Ether lipid metabolism
    113241915 (PLA2G4F)
   00590 Arachidonic acid metabolism
    113241915 (PLA2G4F)
   00591 Linoleic acid metabolism
    113241915 (PLA2G4F)
   00592 alpha-Linolenic acid metabolism
    113241915 (PLA2G4F)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113241915 (PLA2G4F)
   04014 Ras signaling pathway
    113241915 (PLA2G4F)
   04370 VEGF signaling pathway
    113241915 (PLA2G4F)
   04072 Phospholipase D signaling pathway
    113241915 (PLA2G4F)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    113241915 (PLA2G4F)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113241915 (PLA2G4F)
   04664 Fc epsilon RI signaling pathway
    113241915 (PLA2G4F)
   04666 Fc gamma R-mediated phagocytosis
    113241915 (PLA2G4F)
  09152 Endocrine system
   04912 GnRH signaling pathway
    113241915 (PLA2G4F)
   04913 Ovarian steroidogenesis
    113241915 (PLA2G4F)
   04921 Oxytocin signaling pathway
    113241915 (PLA2G4F)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    113241915 (PLA2G4F)
  09156 Nervous system
   04724 Glutamatergic synapse
    113241915 (PLA2G4F)
   04726 Serotonergic synapse
    113241915 (PLA2G4F)
   04730 Long-term depression
    113241915 (PLA2G4F)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113241915 (PLA2G4F)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    113241915 (PLA2G4F)
Enzymes [BR:uah01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.4  phospholipase A2
     113241915 (PLA2G4F)
SSDB
Motif
Pfam: cPLA2_C2 PLA2_B C2
Other DBs
NCBI-GeneID: 113241915
NCBI-ProteinID: XP_026335593
Position
Unknown
AA seq 849 aa
MHRVLGPRWLAGKGLPLLGAVLLRKREKRGLQWRQLRRETHPYYDLQVKVLRARNIQGTD
LLSKADCYVQLCLPTASSSPTRTRMVANCSDPKWDETFHYQIHGAVKNVLELTLYDKDVL
DSDQLSLLLFDLRSLQPGQPYRHTFLLNHQDSQELQVEFFLENSQVPASEVITNGVLVAH
PCLRIQGTLGEDGTAPPREYGCRHIRLTVPGAYEKPQLLPLQPHKEGGLPATFIFHVNPV
ISSRLDVELGEKLTVLQSGPSAELETQTSKLGEGCILLSSLALGQEEQRFVALGEDQEVV
LSMKAEMSSGDLDLRLGFGLCDGEQEFLDKRKQIVSKALQQVLGLSQAPDGGQVPVVAVL
GSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCISTLYQDPAWSQVALQGPIE
RAQARVCSSKMGAMSPERLQYYAQELGSLEGSGHSVSLIDLWGLLIEYFLYQEENPARLS
DQQEAVSQGQNPYPIYASINVRTNISGEDFAEWCEFTPHEVGFPKYGAYVPTELFGSEFF
MGHLLQPRPEPRICYLQGMWGSAFAASVDEIFLKTAGSGLSFLDGHRGKVNITDDCQKLQ
LHDPTRLRTRLFTPQGPFSQAVLDIFTSRFTSAENFNFTRGLCLHKDYVAGREFMAWKAT
HPDAFPNQLTPMRDCLCLVDGGFAINSPFPLNLLPQRAVDLFLSFDYSLEAPFEVLQMTE
KYCLDRGIPFPRIEVLPEDLEEPRECYLFAEAKDPRSPIVLHFPLVNRTFRTHLAPGVER
QTPEEKARGDFAVNGSDTPYGMMNFTYEPEEFERLVALSRYNVLNNAETVRQALRLALQQ
RQAGDRAGG
NT seq 2550 nt   +upstreamnt  +downstreamnt
atgcaccgggtgctcgggccaaggtggctggcaggcaaggggctgcccctcctgggggca
gtgctgctgcgcaagagagagaagaggggacttcagtggaggcaattgcggcgggaaacc
cacccatactatgacctccaggtgaaggtgctgagggccagaaatatccagggcacagat
ctgctgtccaaagccgattgctatgtgcaactgtgcctgcccactgcgtcctccagcccc
acccggacaaggatggtggccaactgcagtgaccccaagtgggatgagaccttccactac
cagatccacggtgctgtgaaaaatgttctggagctcaccctctatgataaggatgtcctg
gacagtgaccagctctccctgctactgtttgacctgaggagcctgcagcctggccaaccc
tacaggcataccttcctactcaaccaccaggattcccaagagctgcaggtggaatttttt
ctggagaacagccaggtgcccgcatctgaagtcatcaccaacggggtcctggtggctcac
ccctgtctgagaatccagggtaccctcggggaagatggcacagctccacctcgagagtat
ggctgtaggcatattcggctgacagtgcccggggcctacgagaagccacagctcttgccc
ctgcaaccccacaaagagggaggccttccagccaccttcatctttcacgtgaatccagtg
atcagctccaggctggatgtggagctgggggagaagctcacagtcctgcagagtggccca
agtgctgaactggagacccagaccagcaagctgggcgaggggtgcatcctgctctcttct
ttggccttaggccaggaggaacagcgtttcgtggccttgggggaggaccaggaggtggtt
ctgagtatgaaggcagaaatgagctctggagaccttgacctgcgccttggctttggcttg
tgtgacggggaacaggagtttctggacaagaggaagcagatcgtgtctaaggccctgcag
caggtgctgggattgagccaggctcctgacggtggccaggtgcctgtggtggctgtgctg
ggttccggaggtggaacccgagccatgtcttccctgtacggcagcctggcagggctgcag
gaactcggcctcctggacactgtgacctacctgagcggggtctctgggtctacctggtgc
atctccaccctctaccaggacccagcctggtcccaggtggccttgcagggccccattgag
cgtgcccaggctcgggtctgcagcagtaagatgggggcgatgtccccggagcgcctgcag
tactacgcccaggaactggggagcttggaaggcagcggccacagtgtttccctcatcgac
ctctggggtctcctcattgaatatttcctctaccaggaggaaaaccccgccaggctgtct
gaccagcaggaggctgtcagccagggccagaacccttacccgatctacgccagcatcaat
gtccgtaccaacatcagcggggaggactttgcagagtggtgcgagttcaccccccatgaa
gtcggcttccccaagtatggggcttatgtccccactgagctctttggctctgagttcttc
atggggcatctgctgcagccccggcccgagccccggatctgctacctgcagggtatgtgg
ggcagtgcctttgcagccagcgtggatgagatcttcctgaagactgctggctcgggcctc
agcttcctagatgggcacagagggaaggtaaacatcacagatgactgccagaagctccag
ctgcatgaccccacacgtctgcgaaccaggctcttcaccccccagggccccttctcccag
gctgtgctggacatattcacctcccgctttacctccgcagagaactttaatttcaccagg
ggcctctgcctacacaaagactatgtagctggccgggagttcatggcctggaaagctacg
caccctgacgccttccccaaccagctcactcccatgcgggactgcctgtgcctggtggat
gggggctttgccatcaactctccgttcccactgaacctgctgccccagagagcggtggac
ctctttctgtcctttgactactccctggaggccccttttgaggtcttacagatgacagag
aagtactgcctggaccgaggcatccccttcccaaggattgaggtgctccctgaggacttg
gaggagccccgagagtgctacctgttcgccgaggccaaggacccccgctcacccattgtg
ctgcacttcccccttgtcaaccgtaccttccgcacacaccttgcaccaggtgtggagcga
caaacacctgaggagaaggcccgtggggactttgccgtcaacgggtcagacacgccctat
ggcatgatgaacttcacctatgagcctgaggagtttgagcggctggtggctctgagtcgc
tacaatgttctgaacaacgcagagaccgtgaggcaggccctccggctggctctgcagcag
cggcaggctggggacagggccgggggctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (23)   
   KEGG PATHWAY (23)   
Chemical substance (14)   
   KEGG COMPOUND (14)   
Chemical reaction (8)   
   KEGG ENZYME (1)   
   KEGG REACTION (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (3)   
   Pfam (3)   
All databases (56)   

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