KEGG   Ursus arctos horribilis (North American brown bear): 113245744
Entry
113245744         CDS       T05909                                 
Symbol
FGFR3
Name
(RefSeq) fibroblast growth factor receptor 3 isoform X1
  KO
K05094  fibroblast growth factor receptor 3 [EC:2.7.10.1]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah01521  EGFR tyrosine kinase inhibitor resistance
uah04010  MAPK signaling pathway
uah04014  Ras signaling pathway
uah04015  Rap1 signaling pathway
uah04020  Calcium signaling pathway
uah04144  Endocytosis
uah04151  PI3K-Akt signaling pathway
uah04550  Signaling pathways regulating pluripotency of stem cells
uah04810  Regulation of actin cytoskeleton
uah05200  Pathways in cancer
uah05206  MicroRNAs in cancer
uah05219  Bladder cancer
uah05230  Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    113245744 (FGFR3)
   04014 Ras signaling pathway
    113245744 (FGFR3)
   04015 Rap1 signaling pathway
    113245744 (FGFR3)
   04020 Calcium signaling pathway
    113245744 (FGFR3)
   04151 PI3K-Akt signaling pathway
    113245744 (FGFR3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    113245744 (FGFR3)
  09144 Cellular community - eukaryotes
   04550 Signaling pathways regulating pluripotency of stem cells
    113245744 (FGFR3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    113245744 (FGFR3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113245744 (FGFR3)
   05206 MicroRNAs in cancer
    113245744 (FGFR3)
   05230 Central carbon metabolism in cancer
    113245744 (FGFR3)
  09162 Cancer: specific types
   05219 Bladder cancer
    113245744 (FGFR3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    113245744 (FGFR3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:uah01001]
    113245744 (FGFR3)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:uah04090]
    113245744 (FGFR3)
Enzymes [BR:uah01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     113245744 (FGFR3)
Protein kinases [BR:uah01001]
 Receptor tyrosine kinases (RTK)
  FGFR family [OT]
   113245744 (FGFR3)
CD molecules [BR:uah04090]
 Proteins
  113245744 (FGFR3)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase I-set Ig_3 ig Ig_2 V-set FGFR3_TM C2-set_2 ABC1 Pkinase_fungal
Other DBs
NCBI-GeneID: 113245744
NCBI-ProteinID: XP_026341802
Position
Unknown
AA seq 807 aa
MGAAARALAFCVAVAVVTGAASGPPGMEQRVVRRAAEAPGPEPGQQEQLVFGSGDTVELS
CHAPAGGPTGPSVWVKDGMGLVPSDRILVGPQRLQVLNASHEDAGAYSCRQRLTQRVLCH
FSVRVTDAPSSGDDEDGEDEAEDTAGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPT
PSISWLKNGKEFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTL
DVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGT
PYVTVLKSWISESVEADARLRLANVSERDGGEYLCRASNFIGVAEKAFWLRVHGPQAAEE
ELVEAGEAGSVYAGVLSYGVGFLLFILVVAAVTLCRLRTPPKKGLGSPTVHKVSRFPLKR
QVTVSLESNSSMNSNTPLVRIARLSSGEGPALANVSELELPADPKWELSRARLTLGKPLG
EGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGRHKNII
NLLGACTQGGPLYVLVEYAAKGNLREYLRARRPPGMDYSFDTCKLPEEQLTCKDLVSCAY
QVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVK
WMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANC
THDLYMIMRECWHAVPSQRPTFKQLVEDLDRVLTVTSTDEYLDLSVPFEQYSPGGQDTPS
SSSSGDDSVFAHDLLPPAPPSSGGPRT
NT seq 2424 nt   +upstreamnt  +downstreamnt
atgggcgccgcggctcgcgccctcgcgttctgcgtggcggtggcggtcgtgaccggagcc
gcctcggggcccccaggcatggagcagcgcgtcgtgcggagagctgcagaggccccggga
cctgaacctggccagcaggagcagctggtctttggcagtggggacaccgtggagctgagc
tgccacgcgcctgccggcggtcccacgggacccagcgtctgggtcaaggacggtatgggg
ctggtgccctcagaccgcatcctggtggggccgcagcggctgcaggtgctcaacgcctcc
catgaggacgccggggcctacagctgccggcagcggctcacccagcgcgttctctgccac
ttcagtgtgcgtgtgacagatgctccgtcctccggagacgacgaagacggggaggatgag
gccgaagatacagcaggggccccttactggacacggcccgagcggatggacaagaagctg
ctggcggtgcctgccgccaacactgtgcgcttccggtgcccggccgccggcaaccccacg
ccgtccatctcctggctgaagaacggcaaggagttccgaggcgagcaccgcatcgggggc
atcaagctgcggcaccagcagtggagcctggtcatggagagcgtggtgccctcggaccgc
gggaactacacgtgcgtcgtggagaacaagttcggcagcatccggcagacctacaccctg
gacgtgctggagcgctctccgcaccggcccatcctgcaggccgggctgcccgccaatcag
acggccgtgctgggcagcgacgtggagttccactgcaaggtgtacagtgacgcacagccc
cacatccagtggctcaagcacgtggaggtgaacggcagcaaagtggggcccgacggcacc
ccctacgtcaccgtgctcaagtcctggatcagtgagagtgtggaggccgacgcacgcctc
cgcctggccaatgtgtccgagcgtgacgggggcgagtacctctgtcgagcctccaatttc
ataggcgtggctgagaaggccttttggctgcgtgttcacgggccccaagcagccgaggag
gagctggtggaggctggtgaggctggcagcgtgtacgcgggagtcctcagctacggggtg
ggcttcctcctcttcatcctggtggtggcggccgtgacactgtgccgcctgcgcacgccc
ccgaagaagggcctgggctcgcccaccgtgcacaaggtctcccgcttcccgctcaagcga
caggtaacagtgtccttggagtccaactcgtccatgaactccaacacgccactggtgcgc
atcgcccggctgtcttctggggagggccctgcgctggccaacgtctctgagctggagttg
cctgctgaccccaagtgggagctgtcccgggcccggctgaccctgggtaagcctctcggg
gagggctgcttcggccaagtggtcatggcggaggccatcggcatcgacaaggaccgggct
gcgaagcccgtcaccgtggccgtgaagatgctgaaagacgacgccacggacaaggacctc
tcggacctggtgtctgagatggagatgatgaagatgatcggccggcacaagaacatcatc
aacctgctgggggcctgcacccagggcgggcccctgtacgtgctggtggagtacgcggcc
aagggcaacctgagggagtacctgcgggcgcggcggcccccgggcatggactactccttc
gacacctgcaagctgccagaggaacagctcacctgcaaggacctggtgtcctgcgcctac
caggtggcacgtggcatggagtacctggcctcgcagaagtgcatccacagggacctggcc
gcgcgcaatgtgctggtgaccgaggacaacgtgatgaagatcgcggacttcggcctggcc
cgtgatgtgcacaaccttgactactacaagaagaccaccaacggccggctgcctgtgaag
tggatggcgcctgaagccttgtttgaccgtgtctacacccaccagagtgacgtctggtcc
tttggggtcctgctgtgggagatcttcaccctggggggctcgccataccccggcatcccc
gtggaggagctcttcaagctgctgaaggagggtcaccgcatggacaagccagccaactgc
acacacgacctgtacatgatcatgcgggagtgttggcacgcggtgccctcccagaggccc
accttcaagcagctggtggaggacctggaccgtgtcctcactgtgacgtccacggatgag
tacctggacctgtctgtgcctttcgagcagtactcgccaggtggccaggacacccccagc
tccagctcctcgggggacgactctgtgtttgcccatgacctgctgcctccagccccaccc
agcagtgggggcccgcggacgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (13)   
   KEGG PATHWAY (13)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (10)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (11)   
   Pfam (11)   
All databases (53)   

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