KEGG   Ursus arctos horribilis (North American brown bear): 113257705
Entry
113257705         CDS       T05909                                 
Symbol
ADCY1
Name
(RefSeq) adenylate cyclase type 1
  KO
K08041  adenylate cyclase 1 [EC:4.6.1.1]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah00230  Purine metabolism
uah01100  Metabolic pathways
uah01522  Endocrine resistance
uah04015  Rap1 signaling pathway
uah04020  Calcium signaling pathway
uah04022  cGMP-PKG signaling pathway
uah04024  cAMP signaling pathway
uah04062  Chemokine signaling pathway
uah04072  Phospholipase D signaling pathway
uah04114  Oocyte meiosis
uah04211  Longevity regulating pathway
uah04213  Longevity regulating pathway - multiple species
uah04261  Adrenergic signaling in cardiomyocytes
uah04270  Vascular smooth muscle contraction
uah04371  Apelin signaling pathway
uah04540  Gap junction
uah04611  Platelet activation
uah04713  Circadian entrainment
uah04714  Thermogenesis
uah04720  Long-term potentiation
uah04723  Retrograde endocannabinoid signaling
uah04724  Glutamatergic synapse
uah04725  Cholinergic synapse
uah04727  GABAergic synapse
uah04750  Inflammatory mediator regulation of TRP channels
uah04911  Insulin secretion
uah04912  GnRH signaling pathway
uah04913  Ovarian steroidogenesis
uah04914  Progesterone-mediated oocyte maturation
uah04915  Estrogen signaling pathway
uah04916  Melanogenesis
uah04918  Thyroid hormone synthesis
uah04921  Oxytocin signaling pathway
uah04923  Regulation of lipolysis in adipocytes
uah04925  Aldosterone synthesis and secretion
uah04926  Relaxin signaling pathway
uah04927  Cortisol synthesis and secretion
uah04928  Parathyroid hormone synthesis, secretion and action
uah04934  Cushing syndrome
uah04935  Growth hormone synthesis, secretion and action
uah04970  Salivary secretion
uah04971  Gastric acid secretion
uah04972  Pancreatic secretion
uah04976  Bile secretion
uah05032  Morphine addiction
uah05142  Chagas disease
uah05146  Amoebiasis
uah05163  Human cytomegalovirus infection
uah05166  Human T-cell leukemia virus 1 infection
uah05200  Pathways in cancer
uah05207  Chemical carcinogenesis - receptor activation
uah05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    113257705 (ADCY1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    113257705 (ADCY1)
   04371 Apelin signaling pathway
    113257705 (ADCY1)
   04020 Calcium signaling pathway
    113257705 (ADCY1)
   04072 Phospholipase D signaling pathway
    113257705 (ADCY1)
   04024 cAMP signaling pathway
    113257705 (ADCY1)
   04022 cGMP-PKG signaling pathway
    113257705 (ADCY1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    113257705 (ADCY1)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    113257705 (ADCY1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113257705 (ADCY1)
   04062 Chemokine signaling pathway
    113257705 (ADCY1)
  09152 Endocrine system
   04911 Insulin secretion
    113257705 (ADCY1)
   04923 Regulation of lipolysis in adipocytes
    113257705 (ADCY1)
   04912 GnRH signaling pathway
    113257705 (ADCY1)
   04913 Ovarian steroidogenesis
    113257705 (ADCY1)
   04915 Estrogen signaling pathway
    113257705 (ADCY1)
   04914 Progesterone-mediated oocyte maturation
    113257705 (ADCY1)
   04921 Oxytocin signaling pathway
    113257705 (ADCY1)
   04926 Relaxin signaling pathway
    113257705 (ADCY1)
   04935 Growth hormone synthesis, secretion and action
    113257705 (ADCY1)
   04918 Thyroid hormone synthesis
    113257705 (ADCY1)
   04928 Parathyroid hormone synthesis, secretion and action
    113257705 (ADCY1)
   04916 Melanogenesis
    113257705 (ADCY1)
   04925 Aldosterone synthesis and secretion
    113257705 (ADCY1)
   04927 Cortisol synthesis and secretion
    113257705 (ADCY1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113257705 (ADCY1)
   04270 Vascular smooth muscle contraction
    113257705 (ADCY1)
  09154 Digestive system
   04970 Salivary secretion
    113257705 (ADCY1)
   04971 Gastric acid secretion
    113257705 (ADCY1)
   04972 Pancreatic secretion
    113257705 (ADCY1)
   04976 Bile secretion
    113257705 (ADCY1)
  09156 Nervous system
   04724 Glutamatergic synapse
    113257705 (ADCY1)
   04727 GABAergic synapse
    113257705 (ADCY1)
   04725 Cholinergic synapse
    113257705 (ADCY1)
   04720 Long-term potentiation
    113257705 (ADCY1)
   04723 Retrograde endocannabinoid signaling
    113257705 (ADCY1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113257705 (ADCY1)
  09149 Aging
   04211 Longevity regulating pathway
    113257705 (ADCY1)
   04213 Longevity regulating pathway - multiple species
    113257705 (ADCY1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    113257705 (ADCY1)
   04714 Thermogenesis
    113257705 (ADCY1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113257705 (ADCY1)
   05207 Chemical carcinogenesis - receptor activation
    113257705 (ADCY1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113257705 (ADCY1)
   05163 Human cytomegalovirus infection
    113257705 (ADCY1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    113257705 (ADCY1)
   05142 Chagas disease
    113257705 (ADCY1)
  09165 Substance dependence
   05032 Morphine addiction
    113257705 (ADCY1)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    113257705 (ADCY1)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    113257705 (ADCY1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    113257705 (ADCY1)
Enzymes [BR:uah01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     113257705 (ADCY1)
SSDB
Motif
Pfam: Guanylate_cyc AC_N Adcy_cons_dom DUF6688 HNOBA
Other DBs
NCBI-GeneID: 113257705
NCBI-ProteinID: XP_026357835
Position
Unknown
AA seq 908 aa
MYGVFVRVLAERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK
PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR
RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL
CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF
LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS
NVMTCEDDDKRRALRTASEKLRNRSSFSANVVYTTPGTRVNRYIGRLLEARQMELEMADL
DFFTLKYKQAERERKYHQLQDEYFTSAVVLALILAALFGLVYLLIIPQSVVVLLLLVFCI
CFLVACVLYLHITRVQCFPGCLTIQIRTVLCIFIVVLIYSVAQGCVVGCLPWAWSSSPNR
SLVTVLTPGGRNAVLPAAPCESAPHALLCGLVGTLPLAIFLRVSSLPKMILLFVLTASYI
LVLELSGYTRASGGGAVSGRSFEPIVAILLFSCTLALHARQVDIKLRLDYLWAAQAEEER
DDMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIE
LDGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKC
ISSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTV
NVASRMDSTGVQGRIQVTEDVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDANGS
QARSLNAERKMCAYGRAGLQTRLATGPPPVGPMIGHPVRAGLGSLQGSGLPPGPHGQHPP
PGAAGKEA
NT seq 2727 nt   +upstreamnt  +downstreamnt
atgtacggggtgtttgtgagggtcctggccgaacgctcccaaaggaaagccttcttgcag
gcccggaactgcatcgaagatcggctgaggctggaggacgagaacgagaagcaggagcgg
ctgcttatgagccttctgccccggaatgttgccatggagatgaaggaggacttcctgaag
ccccctgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc
tttgcggacatcgtgggcttcacgggcctggcgtcacagtgcacggcgcaggagctggtg
aagctgctcaacgagctcttcggcaagtttgatgaactggccacggagaaccactgtcgc
cggatcaagatccttggggactgctattactgcgtgtctggcctcacccagcccaagacc
gaccacgcccactgctgcgtggagatgggtctggacatgatcgacaccatcacgtcggtg
gcagaggccacggaggtggatctgaacatgcgtgtggggctgcacaccggccgggtcctc
tgcggggtcctcggcctgcgcaagtggcagtatgacgtgtggtccaatgacgtgaccctg
gccaatgtaatggaggccgctggcctgcccgggaaggtccacatcacgaagacaaccctg
gcgtgcttgaacggtgactacgaggtggagccgggacacgggcacgagaggaacagcttt
ctgaaagctcacaacatcgagaccttcttcatcgtgccgtcacatcggcggaagatcttt
ccagggctgatcctttcggacataaagcccgccaagaggatgaagttcaagaccgtgtgc
tacctgctggtgcagctcatgcactgtcggaagatgttcaaggcggagatccccttctcc
aacgtcatgacgtgcgaggatgacgacaagcggagggcgttgagaactgcgtcagaaaaa
ctcagaaaccgctcgtccttctctgcgaatgtcgtctataccaccccgggcacgcgcgtc
aacaggtacatcggccgcctcctagaagcgcgccagatggagctggagatggcggacctg
gacttcttcaccctgaagtataagcaggctgagcgcgagcgcaagtaccaccagctccag
gatgagtatttcaccagtgccgtcgtgcttgcgctcatcctggctgccttgtttggcctc
gtctaccttctcatcatcccgcagagcgtggtcgtcctcctgctgctggtgttctgcatc
tgcttcctggtggcctgtgtcctgtacctgcacatcacccgggtccagtgttttccagga
tgcctgacgatccagatccgcaccgtcttgtgtattttcatagtggtcctcatctactcg
gtggcccaaggatgtgtggtgggctgcctgccctgggcctggagctccagccccaacagg
tccctggtgaccgtcctgacccctggtggccggaacgccgtgctgcctgctgcaccctgc
gagtctgcaccccacgccctgctctgtggcctcgtgggcaccctgccactggccatcttc
ctgcgggtgtcctccctgcccaaaatgatcctgctcttcgtgctcacggcgtcctacatc
ctggtcctggagctcagcgggtacaccagggcctcagggggcggtgcggtgtccgggcgc
agcttcgagccgatcgtggccatcctgctgttctcgtgcacgctggccctgcacgcccgg
caggtggacatcaagctgcggctggactatctctgggcagcacaggcagaggaggagagg
gacgacatggagagggtgaagctggacaacaagaggattctcttcaacctcctgccagcc
cacgtcgcccagcacttcctcatgtccaacccccggaacatggacctgtactaccagtcc
tactcgcaggtgggcgtcatgttcgcctccatccccaactttgatgacttctacatcgag
ctggatggcaacaacatgggggtggagtgtctgcgccttctgaatgagatcatcgctgac
tttgacgagctcatggacaaagacttctacaaggacctggagaagatcaagaccatcggg
agcacctatatggctgcggtgggactagcacccacgaccgggaccaaggcaaagaagtgc
atctcctcgcacctcagcacgctggcggactttgccatcgagatgttcgacgtcctggat
gaaatcaactaccagtcttacaacgactttgtgctccgtgtcggcatcaacgttggcccc
gtggtggccggggtgatcggggctcgaaggccgcagtacgacatctggggaaacacggtc
aatgtggccagtaggatggacagcacgggtgtccagggcagaatccaggtgaccgaggac
gttcaccggctgctgcgaaggggcacttaccgcttcgtgtgccgcgggaaggtcagcgtc
aagggcaagggtgagatgctgacgtacttcctggaaggccggaccgatgcaaacggctcc
caggccaggtccctgaatgcagagcggaaaatgtgcgcttacgggcgagccggcctccag
accagactggccacaggcccgcccccggtgggccccatgatcggccacccggtcagagcc
gggctggggtctctgcagggctcggggctccccccaggcccccacggccagcacccgccc
cccggagcagctggaaaggaggcttag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (52)   
   KEGG PATHWAY (52)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (73)   

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