KEGG   Ursus arctos horribilis (North American brown bear): 113257950
Entry
113257950         CDS       T05909                                 
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6
  KO
K05697  tyrosine-protein phosphatase non-receptor type 6 [EC:3.1.3.48]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah04148  Efferocytosis
uah04520  Adherens junction
uah04630  JAK-STAT signaling pathway
uah04650  Natural killer cell mediated cytotoxicity
uah04660  T cell receptor signaling pathway
uah04662  B cell receptor signaling pathway
uah05140  Leishmaniasis
uah05205  Proteoglycans in cancer
uah05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    113257950 (PTPN6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    113257950 (PTPN6)
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    113257950 (PTPN6)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    113257950 (PTPN6)
   04660 T cell receptor signaling pathway
    113257950 (PTPN6)
   04662 B cell receptor signaling pathway
    113257950 (PTPN6)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    113257950 (PTPN6)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    113257950 (PTPN6)
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    113257950 (PTPN6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:uah01009]
    113257950 (PTPN6)
Enzymes [BR:uah01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.48  protein-tyrosine-phosphatase
     113257950 (PTPN6)
Protein phosphatases and associated proteins [BR:uah01009]
 Protein tyrosine phosphatases (PTPs)
  Class I PTPs (Classical)
   Non-receptor PTPs
    113257950 (PTPN6)
SSDB
Motif
Pfam: Y_phosphatase SH2 DSPc PTPlike_phytase Y_phosphatase3
Other DBs
NCBI-GeneID: 113257950
NCBI-ProteinID: XP_026358338
Position
Unknown
AA seq 595 aa
MVRWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGDF
YDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGGQA
ETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTVGG
SETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESEDTA
KAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQGRDSNIPGSD
YINANYVKNELLGPDENTKTYIASQGCLEATVNDFWQMAWQENTRVIVMTTREVEKGRNK
CVPYWPEVGTQRVYGPYVVTNCREHDTAEYKLRTLQVSPLENEDLVREIWHYQYLSWPDH
GVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGLDC
DIDVQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVMQSQKGRESEYGNIT
YPPAMKNAHAKASRTSSKHKEDVYENLHSKNKKEEKVKKQRSADKEKSKGSLKRK
NT seq 1788 nt   +upstreamnt  +downstreamnt
atggtgaggtggtttcaccgagacctcagcgggctggacgcggaaaccctgctcaagggc
cgcggcgtccacgggagcttcttggctcggcccagtcgcaagaaccagggtgacttctcc
ctctctgtcagggtgggggatcaggtgacccacattcggatccagaactcgggcgatttc
tatgacctgtatggaggggagaagtttgcaacactcacagagctcgtggagtactacacg
cagcagcagggcgtcctgcaggatcgagacggcaccatcatccacctcaagtacccgctg
aactgctccgaccccaccagcgagaggtggtaccatggtcacatgtctggggggcaggca
gagacactgctgcaggccaagggtgaaccctggacatttctcgtgcgtgagagcctcagc
cagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggcccaggctcc
ccactcagagtcactcatatcaaggtcatgtgtgagggcggacgctacaccgtgggtggt
tcagagaccttcgacagcctcacagacctggtggagcatttcaagaagacagggattgag
gaggcctcaggtgccttcgtctacctgcggcagccatactatgccactcgggtgaacgca
gctgacattgaaaaccgggtcttggaactcaacaagaagcaggagtcagaggacacagcc
aaagccggcttctgggaggagtttgagagtctgcagaagcaggaggtaaagaacttgcat
cagcggctggaagggcagcggccagagaacaagagcaagaaccgatacaagaacattctc
ccatttgaccacaccagagtgatcctacagggacgcgacagtaacatccctgggtccgac
tacatcaacgccaactacgtcaagaacgagctgctaggccctgatgagaacactaagacc
tacatcgccagccagggatgcctggaggccacagtcaacgacttctggcagatggcatgg
caggagaatacccgcgtcatcgtcatgaccacccgagaggtggagaaaggccggaacaag
tgtgtcccgtattggccggaggtgggcactcagcgtgtctacggaccctacgtggtaacc
aactgcagggaacatgacacagctgagtacaagctccgaaccttacaggtctccccgctg
gaaaatgaggacctggttcgagagatctggcactaccagtacctgagctggcctgaccat
ggggtccccagtgagcctgggggtgtcctcagcttcctggaccagatcaaccagcggcag
gaaagtctgcctcatgcgggacccatcatcgtgcattgcagcgcaggcattggccgcacg
ggcaccatcatcgtcatcgacatgctcatggagagcatctccaccaaggggctggactgc
gacatcgacgtccagaagaccatccagatggtgcgggcgcagcgctcaggcatggtgcag
acggaggcgcagtacaagttcatctatgtggccattgcccagttcatcgaaaccaccaag
aagaagctggaggtcatgcagtcccagaagggccgggagtcagagtacgggaacatcacc
taccccccggccatgaagaacgcccatgccaaggcctcccgcacctcttccaaacacaag
gaggatgtatatgagaacttgcacagtaagaacaagaaggaggagaaggtgaagaagcag
cggtcggcggacaaggagaagagcaagggttcccttaagaggaagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (9)   
   KEGG PATHWAY (9)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (26)   

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