KEGG   Ursus arctos horribilis (North American brown bear): 113269168
Entry
113269168         CDS       T05909                                 
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah04020  Calcium signaling pathway
uah04022  cGMP-PKG signaling pathway
uah04024  cAMP signaling pathway
uah04148  Efferocytosis
uah04260  Cardiac muscle contraction
uah04261  Adrenergic signaling in cardiomyocytes
uah04380  Osteoclast differentiation
uah04919  Thyroid hormone signaling pathway
uah04972  Pancreatic secretion
uah05010  Alzheimer disease
uah05017  Spinocerebellar ataxia
uah05022  Pathways of neurodegeneration - multiple diseases
uah05410  Hypertrophic cardiomyopathy
uah05412  Arrhythmogenic right ventricular cardiomyopathy
uah05414  Dilated cardiomyopathy
uah05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uah00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    113269168 (ATP2A3)
   04024 cAMP signaling pathway
    113269168 (ATP2A3)
   04022 cGMP-PKG signaling pathway
    113269168 (ATP2A3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    113269168 (ATP2A3)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    113269168 (ATP2A3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    113269168 (ATP2A3)
   04261 Adrenergic signaling in cardiomyocytes
    113269168 (ATP2A3)
  09154 Digestive system
   04972 Pancreatic secretion
    113269168 (ATP2A3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    113269168 (ATP2A3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    113269168 (ATP2A3)
   05017 Spinocerebellar ataxia
    113269168 (ATP2A3)
   05022 Pathways of neurodegeneration - multiple diseases
    113269168 (ATP2A3)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    113269168 (ATP2A3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    113269168 (ATP2A3)
   05414 Dilated cardiomyopathy
    113269168 (ATP2A3)
   05415 Diabetic cardiomyopathy
    113269168 (ATP2A3)
Enzymes [BR:uah01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     113269168 (ATP2A3)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD TNP-like_RNaseH_N DUF3106
Other DBs
NCBI-GeneID: 113269168
NCBI-ProteinID: XP_026373699
Position
Unknown
AA seq 999 aa
MEAAHLLPAADVLSRFSVTVESGLRPEQVSGARERYGPNELPTEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLACFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRVRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAIPDPRAVNQDKKNMVFSGTNIASGKALGVAVATGLHTELGKIRSQMA
AVEPERTPLQHKLDEFGRQLSRAISVICVAVWVINISHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGTCRLHEFTISGTTYAPEGEVRQAEQLVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTNLQTLSPVERASACNAVIKQLMR
KEFTLEFSRDRKSMSVYCTPTSPGLAAQGSKMFVKGAPESVIERCSSVRVGSHTVPLNAT
SREQILAKIRDWGSGSDMLRCLALATRDSPPRKEDMQLDNCSKFVQYEMDLTFVGCVGML
DPPRPEVAACITRCHQAGIRVVMITGDNKGTAVAICRRLGIFRDTEDVVGKAYTGREFDD
LSPEQQRHACRTACCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKMPRNPHEALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPHVTFYQLRNFLKCSEDNPLFADIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVLVLQISLPVILLDEALKYLSRNHMDEEKDQK
NT seq 3000 nt   +upstreamnt  +downstreamnt
atggaggcggcgcacctgctcccggctgcagacgtgctgagccgcttctcggtgacggtc
gagagcggactgaggccggagcaggtgtctggcgcgcgggagcgctacggccccaacgag
ctcccaactgaggaagggaagtccctgtgggagctggtgctggagcagtttgaggacctc
ctggtgcgcatcctgctgttggctgccctggtctccttcgtcctggcctgctttgaggag
ggcgaagagaccacgacagccttcgtggagcccctggtcatcatgttgatccttgtggcc
aatgctatcgtgggcgtatggcaggaacgcaatgctgagagtgccattgaggccttgaag
gagtatgagcctgagatgggcaaggtgatccgctcagaccgcaaaggtgtgcagagggtc
cgcgcccgggacatcgtccctggagacatcgtggaggtggcagtgggagacaaagtaccc
gctgacctccgcctcatcgagatcaagtccaccacactgagagtagaccagtccatcctg
acaggtgaatccgtgtctgtgaccaagcacacagatgccatcccagatcccagagctgtg
aaccaggacaagaagaacatggttttctctggcaccaatatcgcatcaggcaaggccctg
ggtgtggcagtggccacaggcctgcacacagagctgggtaagatccggagtcagatggcg
gcagtggagccggagcggacgccgctgcagcacaagctggatgagtttgggcggcagctg
tcccgtgccatctctgtgatctgtgtggctgtgtgggtcatcaacatcagccactttgct
gacccggcccatggtggctcctggctccgtggtgctgtctactacttcaagattgccgtg
gccctggcggtggctgccatccctgagggcctcccagccgttatcactacatgcctggct
ctgggcacacggcgcatggcacgcaagaatgccattgtgcgaagcctgccctctgtggag
accctgggctgcacctcagtcatctgctccgacaagacaggcacactcaccaccaatcag
atgtctgtctgccggatgttcgtggtagccgaggccgaagcaggcacctgccgtttgcac
gagttcaccatctcaggcaccacttatgccccggagggcgaagtgaggcaggcggagcag
cttgtgcgctgtgggcagtttgatgggctggtggagctggcgacaatctgtgccctgtgc
aatgactcagcgctggactacaacgaggctaagggcgtgtatgagaaggtgggagaggcc
acggagactgctctgacttgcctggtggagaaaatgaatgtgtttgacaccaacctacag
accctctccccggtggagcgagccagtgcctgcaatgcggtcatcaagcagctgatgcgg
aaggagtttactttggagttctcccgagaccggaagtccatgtcagtgtactgcacaccg
actagccctggcctggcagcccagggcagcaagatgtttgtgaagggggctcctgagagt
gtgatcgagcgctgtagctcagtccgagtgggaagccatacagtacccctgaatgccacc
tccagggagcagatcttggccaagattcgggattggggctcaggctcagacatgttgcgc
tgcctggcactggccactcgggattcacccccaaggaaggaggacatgcagctggacaac
tgcagcaagtttgtgcaatacgagatggacctcacttttgtgggctgcgtgggcatgctg
gaccctccaaggcccgaggtggctgcttgtatcacacgctgccaccaggccggcatccgt
gtggtcatgatcacaggggacaacaaaggcacagctgtggccatctgccgccggcttggc
atcttcagggacacagaggacgtggtggggaaggcctacacaggtcgcgaattcgatgac
ctcagccctgagcagcagcgccatgcctgccgcacagcatgctgttttgcccgtgtggaa
cctgcacacaagtcccgaatcgtagagaacctacagtccttcaacgagatcactgccatg
actggagacggggtgaatgatgccccagctttgaagaaagcagagattggcattgccatg
ggctctggcacagctgtagccaagtcagcagccgagatggtgctgtcagatgacaacttt
gcctccatcgtggctgcagtggaggagggccgggccatctacaacaacatgaagcaattc
atccgctacctcatctcctccaatgtaggcgaggttgtctgcatcttcctcacggcaatt
ctgggcctcccggaagccctgatccctgtgcagctgctctgggtgaacctggtgacagat
ggtctacctgccacagccctgggcttcaaccccccagacctggacatcatggagaagatg
ccgaggaaccctcatgaggccctcatcagtggctggctcttttttcgatatctggctatt
ggagtgtacgtaggcctggccacggtggctgccgccacctggtggttcctttatgatgcc
gagggacctcacgtcaccttctaccaactgaggaacttcctgaagtgctccgaggacaac
ccactctttgccgacattgactgcgaggtcttcgagtcacgctttcccacaaccatggcc
ttgtctgtgctggtgaccattgaaatgtgcaatgccctcaacagtgtctcagagaaccag
tcgctgctgcggatgccaccctggctgaacccttggctgctggcagctgtggccatgtcc
atggccctgcacttcctcatccttctggtgccacccctgcctcttattttccaggtgacc
ccactgagcgggcgccagtgggtgctggtgctccagatatctctgcctgtcatccttctt
gatgaagccctcaagtacctgtcccggaaccacatggatgaagaaaaggaccagaagtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (4)   
   RefSeq(pep) (4)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (9)   
   Pfam (9)   
All databases (40)   

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